Skönlitterär bok för åldern 9-12 år.Vad är egentligen mod? Kan man lära sig att bli modig? Det frågar sig Malva, elva år, när hon inte lyckas stå inför hela klassen i skolan och berätta om sitt sommarlov. Inte ett vettigt ord får hon fram. De andra barnen fnissar och fröken suckar. En trasig flaskpost blir Malvas räddning. Genom det mystiska receptet i flaskan blir hon mindre än en tumme. Och sugs

Background: There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. The aim of this study was to investigate clinical efficacy and tolerability of abatacept in RA, using a national register. Methods: RA patients that

We present a novel family of deep neural architectures, named partially exchangeable networks (PENs) that leverage probabilistic symmetries. By design, PENs are invariant to block-switch transformations, which characterize the partial exchangeability properties of conditionally Markovian processes. Moreover, we show that any block-switch invariant function has a PEN-like representation. The DeepSe

A continuous-wave (CW) Scheimpflug underwater multi-spectral lidar system was constructed to monitor aquatic fauna with spatial, spectral, and temporal resolution. Utilizing a 1 W 414 nm diode laser and a detection set-up with a reflective grating, measurements of shrimp pleopod movements at fixed range, and the swimming of small fish trapped in a clear tube were performed in a 5 m ×0.6 m ×0.6 m w

Purpose: This paper sets out to examine how CEOs’ talk of sustainability has developed in a period of increased expectations from society for companies to step up their transformation towards more sustainable businesses andbetter account for their progress and performance within the sustainability area.Design/methodology/approach: By adopting an interpretive textual approach, this paper provides a

Results are presented from the measurement by ATLAS of long-range (| Δ η| > 2) dihadron angular correlations in s=8 and 13 TeV pp collisions containing a Z boson. The analysis is performed using 19.4 fb - 1 of s=8 TeV data recorded during Run 1 of the LHC and 36.1 fb - 1 of s=13 TeV data recorded during Run 2. Two-particle correlation functions are measured as a function of relative azimuthal angl

Mercury is one of the most toxic elements threatening the biosphere, with levels steadily rising due to both natural and human activities. Selenium is an essential micronutrient, required for normal development and functioning of many organisms. While selenium is known to counteract mercury's toxicity under some conditions, to date information about the mercury-selenium relationship is fragmented

Humans are environmentally exposed to potentially toxic Cd and Hg species and to the Hg compound thimerosal (THI), an antibactericidal vaccine additive. Previous studies have revealed that Cd2+, Hg2+ and CH3Hg+ are taken up by red blood cells (RBCs) and bind to cytosolic glutathione (GSH) and/or hemoglobin (Hb). Since interactions in the cytosol of RBCs may be linked to their hemolysis, a more com

The compounds of mercury can be more toxic than those of any other non-radioactive heavy element. Despite this, environmental mercury pollution and human exposure to mercury are widespread, and are increasing. While the unusual ability of selenium to cancel the toxicity of mercury compounds has been known for nearly five decades, only recently have some aspects of the molecular mechanisms begun to

Environmental context Chronic ingestion of arsenic leads to its accumulation in keratinous tissues, which can represent a risk factor for developing cancer. We use synchrotron X-ray absorption spectroscopy to investigate chemical bonding of arsenic in the keratins from nail clippings of volunteers from areas in Atlantic Canada with low-to-moderate arsenic contamination of drinking water. The study

1989 was a turning point in the socio-economic development in the former Eastern bloc, initiating a systemic transformation that affected the society at large. It also contributed to the crystallisation of certain cultural landscapes, hitherto largely illegible due to the inhibition of spatial processes encountered during socialism. In Poland, after a quarter-century of a free market economy, the

Background: With the increasing use of robot-assisted techniques for urologic and gynecologic surgery in patients with severe comorbidities, the risk of a critical incidence during surgery increases. Due to limited access to the patient the start of effective measures to treat a life-threatening emergency could be delayed. Therefore, we tested the management of an acute emergency in an operating r

Today, there are increased expectations that welfare employees should conduct service innovative improvements that enable more effective ways to meet the needs of children.In this study we use the definition of ‘service innovation’ as a way to change the value-adding process of the user so that it becomes better for the end-user than it was before, such as easier to handle things or situations. In

BACKGROUND: A slight increase in revisions for infected joint arthroplasties has been observed in the Nordic countries since 2000 for which the reasons are unclear. However, in 2007 a Swedish study of the timing for prophylactic antibiotics in a random sample of knee arthroplasties found that only 57% of the patients had received the antibiotic during the optimal time interval 45-15 minutes before

Objective: A widely recognized metabolic side effect of glucocorticoid (GC) therapy is steroid-induced diabetes mellitus (DM). However, studies on the molecular basis of GC-induced pancreatic beta cell dysfunction in human beta cells are lacking. The significance of non-coding RNAs in various cellular processes is emerging. In this study, we aimed to show the direct negative impact of GC on beta c