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Background: Diabetic retinopathy and retinopathy of prematurity are diseases caused by pathological angiogenesis in the retina as a consequence of local hypoxia. The underlying mechanism for epiretinal neovascularization (tuft formation), which contributes to blindness, has yet to be identified. Neural cell adhesion molecule (N-CAM) is expressed by Muller cells and astrocytes, which are in close c
Aims To compare the British Isles Lupus Assessment Group (BILAG) 2004, the Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) flare index (SFI) and physician's global assessment (PGA) in assessing flares of disease activity in patients with systemic lupus erythematosus (SLE). Methods Sixteen patients with active SLE were assessed by a panel of 16 rheumatologists. The order in
Popular Abstract in Swedish Psoriasis är en av våra vanligaste folksjukdomar, som drabbar 2-3 % av den vuxna befolkningen. Man vet i dag att många patienter med psoriasis lider av psykisk ohälsa och sänkt livskvalitet. Sjukdomen i sig innebär ofta en stor psykologisk påfrestning för patienten, men stress och psykisk ohälsa också kan vara en viktig orsak till insjuknande och återfall av psoriasis. Psychological distress is well known to be associated with psoriasis, both as a disease consequence, and as a causative factor for onset and exacerbations. Psychoneuroimmunological mechanisms have been suggested to be involved in the pathogenesis of psoriasis and have often been shown to be related to psychological distress and pruritus in psoriasis. The general aim of this thesis was to investig
Forskarutbildningen har ett dubbelt syfte, att utbilda framtidens universitetslärare och forskare samt att utgöra rekryteringsbas för andra delar av offentlig sektor och privat sektor. Resultaten av denna alumnundersökning visar att Lunds universitet väl svarar upp mot detta dubbla rekryteringssyfte. Av doktoranderna i undersökningen, riktad till examinerade år 2004, hade nästan nästan samtliga (9
Expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate with favourable clinicopathological parameters and prognosis in several cancer diseases. The aim of this study was to examine the expression and prognostic ability of RBM3 in patients with testicular non-seminomatous germ cell tumours (NSGCT).
Purpose – The aim is to understand customers' willingness, or unwillingness, to pay a price premium in the market for consumer packaged food and what kind of images brands can use in order to achieve a price premium. Design/methodology/approach – The study is based on a quantitative survey of brand images found in food and branding literature and their impact on loyalty as well as customers' will
The general research question of the present study was to assess the impact of visually salient online adverts on children's task-oriented internet use. In order to answer this question as reliably as possible, an experimental study was constructed in which 9-year-old and 12-year-old Swedish children were asked to solve a number of tasks while interacting with a mockup website. In each trial, web
Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3
Controlled vocabularies (CVs), i.e. a collection of predefined terms describing a modeling domain, used for the semantic annotation of data, and ontologies are used in structured data formats and databases to avoid inconsistencies in annotation, to have a unique (and preferably short) accession number and to give researchers and computer algorithms the possibility for more expressive semantic anno
Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i
Recension av Ian Buruma, Skuldbördan – hur Tyskland och Japan har gjort upp med andra världskriget.
This paper presents a three-dimensional sequentially coupled thermo-mechanical analysis of the friction stir welding process suitable for residual stress prediction. A friction stir butt weld of the aluminium alloy 2024 T3 is simulated using finite element analysis. The thermal model includes diffusive heat transfer in the work pieces and that backing plate, convective heat transfer in the work pi
Many birds use a flight mode called undulating or flap-gliding flight, where they alternate between flapping and gliding phases, while only a few bats make use of such a flight mode. Among birds, flap-gliding is commonly used by medium to large species, where it is regarded to have a lower energetic cost than continuously flapping flight. Here, we introduce a novel model for estimating the energet
Intervju: "När vi andra ser gungor, rutschbanor och berg- och dalbanor ser Ann-Marie Pendrill mängder av tillfällen att uppleva, prata om och räkna med fysik. – Fysik är ett lekfullt ämne."
