Molecular mechanisms behind increased cerebral vasospasm and local inflammation in late cerebral ischemia after subarachnoid hemorrhage (SAH) are poorly elucidated. Using system biology tools and experimental SAH models, we have identified signal transducer and activator of transcription 3 (STAT3) transcription factor as a possible major regulatory molecule. On the basis of the presence of transcr

To establish the concentrations of iodine contrast media (I-CM) iso-attenuating with 0.5M gadolinium contrast media (Gd-CM), regarded diagnostic in catheter angiography and vascular interventions in azotemic patients, at various X-ray tube potentials with correlation to skin radiation dose.

Elevated prediagnostic testosterone and insulin-like growth factor I (IGF-I) concentrations have been proposed to increase risk of hepatocellular carcinoma (HCC). However, the metabolism of these hormones is altered as a consequence of liver damage and they may have clinical utility as HCC risk markers. A case-control study was nested within the European Prospective Investigation into Cancer and N

The identification of genetic causes for Mendelian disorders has been based on the collection of multi-incident families, linkage analysis, and sequencing of genes in candidate intervals. This study describes the application of next-generation sequencing technologies to a Swiss kindred presenting with autosomal-dominant, late-onset Parkinson disease (PD). The family has tremor-predominant dopa-res

Understanding the mechanisms governing chemical and morphological changes induced by an ambient-pressure gas and how such changes influence the activity of heterogeneous catalysts is central to the formation of a predictive capability for structure-reactivity relationships. With techniques such as ambient-pressure photoelectron spectroscopy, scanning tunneling microscopy, and surface X-ray diffrac

Chemical solution deposition (CSD) offers the opportunity to fabricate very thin electrolyte films at lower temperatures than traditional powder-based methods. CSD methods have not been used much in production of protonic ceramic fuel cells (PCFC) until now. In this contribution we describe thin film deposition of the two proton-conducting materials BaZr0.9Y0.1O3 (-) (delta) (BZY) and La28 - xW4 +

Abstract in UndeterminedIn many industries, a national accident investigation board conducts investigations following major accidents. For safety improvements to be achieved, however, it is essential that the recommendations presented in these investigations are followed by necessary actions. In this paper, challenges related to implementation of recommendations from accident investigations are st

The purpose was to describe posture, ability to change position, and association between posture and contractures, hip dislocation, scoliosis, and pain in young adults with cerebral palsy (CP).

Epidemiological studies reveal growing evidence that most cases of Alzheimer`s Disease (AD) likely involve a combination of genetic and environmental risk factors. Identifying and validating these risk factors remains one of the most critical scientific challenges. Several diseases appear to have strong implications for neurodegeneration leading to dementia. This risk encompasses different forms o

The ForSAFE-VEG model was used to investigate the impacts of climate change and air pollution scenarios on soil chemistry and ground vegetations composition. In particular, the model involves a ground vegetation model incorporating plant changes to ambient site conditions in terms of climate and chemistry, but the model also incorporate competition between the different plant groups. The model was

Accumulating data suggest that platelets not only regulate thrombosis and haemostasis but also inflammatory processes. Platelets contain numerous potent pro-inflammatory compounds, including the chemokines CCL5 and CXCL4 although their role in acute colitis remains elusive. The aim of this study was to examine the role of platelets and platelet-derived chemokines in acute colitis. Acute colitis wa

Diagnosis of acute arterial mesenteric ischemia in the early stages is now possible using modern computed tomography with intravenous contrast enhancement and imaging in the arterial and/or portal phase. Most patients have acute superior mesenteric artery (SMA) occlusion, and a large proportion of these patients will develop peritonitis prior to mesenteric revascularization, and explorative laparo

We investigate whether Swedish Environmental Protection Agency (EPA) administrator recommendations regarding improvements in environmental quality differ from citizen preferences. This is done by conducting identical choice experiments on both citizens and administrators at the EPA. The administrators were asked to choose the alternatives they would recommend as a policy, while the citizens were a

It has long been recognised that nitric oxide (NO) and nitrogen dioxide (NO2) can promote the oxidation of methane and other hydrocarbons under various fuel-lean and fuel-rich conditions and a range of temperatures and pressures conditions. However, despite the ease with which NO and NO2 interconvert under the oxidation conditions, the reactions responsible for initiating the oxidation process for

Disperse dyes are well-known contact sensitizers. However, they are not included in the majority of commercially available baseline patch test series.