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Objectives: low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism. Methods: maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/ obesity (n = 31) and their infants at birt

Prognostic impact of tumor-specific insulin-like growth factor binding protein 7 (IGFBP7) levels in breast cancer : A prospective cohort study

The prognostic impact of insulin-like growth factor binding protein 7 (IGFBP7) in breast cancer is unclear. Host factors, including lifestyle, anthropometry and metabolic profile, might influence tumor-specific IGFBP7. This study aimed to investigate whether IGFBP7 levels and messenger ribonucleic acid (mRNA) expression are associated with the patient and tumor characteristics and prognosis in bre

Repeated seasonal influenza vaccination among elderly in Europe: Effects on laboratory confirmed hospitalised influenza

In Europe, annual influenza vaccination is recommended to elderly. From 2011 to 2014 and in 2015-16, we conducted a multicentre test negative case control study in hospitals of 11 European countries to measure influenza vaccine effectiveness (IVE) against laboratory confirmed hospitalised influenza among people aged ≥65years. We pooled four seasons data to measure IVE by past exposures to influenz

Measurement of the production cross section of pairs of isolated photons in pp collisions at 13 TeV with the ATLAS detector

A measurement of prompt photon-pair production in proton-proton collisions at s = 13 TeV is presented. The data were recorded by the ATLAS detector at the LHC with an integrated luminosity of 139 fb−1. Events with two photons in the well-instrumented region of the detector are selected. The photons are required to be isolated and have a transverse momentum of pT,γ1(2)> 40 (30) GeV for the leading

Patients' experiences before, during, and after a colonoscopy procedure : A qualitative study

Although colonoscopy is a common examination, there is limited research focusing on how patients experience this procedure. It is important that a colonoscopy is tolerated, as it may lead to lifesaving diagnostics and treatment. This study aims to explore adult patients' experience of undergoing a colonoscopy regarding the time prior to, during, and after the procedure. This was a qualitative stud

Immediate Full Weight-Bearing Versus Partial Weight-Bearing After Plate Fixation of Distal Femur Fractures in Elderly Patients. A Randomized Controlled Trial

Introduction: After surgery for distal femur fractures in elderly patients, weight-bearing is commonly restricted. Immediate non-restrictive weight-bearing might have beneficial effects. There are no randomized studies on the topic. The purpose of this study was to compare the functional outcome between immediate full weight-bearing (FWB) as tolerated and partial weight-bearing (PWB) during the fi

Symbolae sacrae : Symbolic formulae for protection and adoration within the quarries of Gebel el-Silsila

Within the grand sandstone quarries of Gebel el-Silsila is a vast amount of unique symbolic representations; stylized iconographic and pseudo-scripted signs and marks that to some extent signify deities and their protection against demons, evil and mishaps. Like written protective formulae, these marks were placed within the quarries to symbolically safe-keep the quarry workers, and for expressing

Patients' Perceptions of Person-Centered Care in Early Rheumatoid Arthritis: A Qualitative Study

ObjectiveMost research on patient experiences of rheumatoid arthritis (RA) care is performed with patients who have established RA and less often with patients with early RA. Experiences of and expectations about health care may change over time, which is why the aim was to explore patients’ perceptions of person-centered care (PCC) early in the RA disease course.MethodsThirty-one patients with ea

Sentiments of Segregation : The Emotional Politics of Apartheid in South Africa, c. 1948-1990

This dissertation studies the relationship between emotions and the everday application of apartheid in South Africa between 1948 and 1990. Histories of apartheid have long been politics-driven, focusing on the rise and fall of the regime with its reception being studied primarily through the lens of the popular struggle that, in part, led to apartheid’s downfall. Thus, the lived experience and re

Healthy Lifestyle and Mortality Among Adults Receiving Hemodialysis : The DIET-HD Study

Rationale & Objective: A healthy lifestyle promotes cardiovascular health and reduces cardiac-related mortality in the general population, but its benefits for people receiving maintenance hemodialysis are uncertain. Study Design: Prospective cohort study. Setting & Participants: 5,483 of 9,757 consecutive adults receiving maintenance hemodialysis (January 2014 to June 2017, median dialysi

Den andra Rawls

Stämmer föreställningen att John Rawls rättviseteori i A Theory of Justice är en empiriskt oförankrad analytisk konstruktion? Halldenius hävdar att den inte gör det. Rawls yttersta bevekelsegrunder var etiska, hans etik vardaglig och psykologisk och hans ambition att analysera människan i sitt samhälleliga sammanhang. Rättviseprincipernas universalitet till trots är rättvisans fråga ändå alltid en

Independent validation of a pre-specified four-kallikrein marker model for prediction of adverse pathology and biochemical recurrence

Background: Accurate markers for prostate cancer (PC) risk stratification could aid decision-making for initial management strategies. The 4Kscore has an undefined role in predicting outcomes after radical prostatectomy (RP). Methods: We included 1476 patients with 4Kscore measured prior to RP at two institutions. The 4Kscore was assessed for prediction of adverse pathology at RP and biochemical r

Regulating genetic engineering guided by human dignity, not genetic essentialism

How might a liberal democratic community best regulate human genetic engineering? Relevant debates widely deploy the usually undefined term “human dignity.” Its indeterminacy in meaning and use renders it useless as a guiding principle. In this article, I reject the human genome as somehow invested with a moral status, a position I call “genetic essentialism.” I explain why a critique of genetic e