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Consensus statement of the European Heart Rhythm Association: updated recommendations for driving by patients with implantable cardioverter defibrillators

Patients with an implantable cardioverter defibrillator (ICD) have an ongoing risk of sudden incapacitation that might cause harm to others while driving a car. Driving restrictions vary across different countries in Europe. The most recent recommendations for driving of ICD patients in Europe were published in 1997 and focused mainly on patients implanted for secondary prevention. In recent years

Zn2+ binding to human calbindin D(28k) and the role of histidine residues.

We have studied the binding of Zn2+ to the hexa EF-hand protein, calbindin D(28k)-a strong Ca2+-binder involved in apoptosis regulation-which is highly expressed in brain tissue. By use of radioblots, isothermal titration calorimetry, and competition with a fluorescent Zn2+ chelator, we find that calbindin D(28k) binds Zn2+ to three rather strong sites with dissociation constants in the low microm

Numerical investigation of the effect of different back sweep angle and exducer width on the impeller outlet flow pattern of a centrifugal compressor with vaneless diffuser

This paper presents a numerical investigation of the effect of different back sweep angles and exducer widths on the steady-state impeller outlet flow pattern of a centrifugal compressor with a vaneless diffuser. The investigations have been performed with commercial computational fluid dynamics (CFD) and in-house programmed one-dimensional (ID) codes. CFD calculations aim to investigate how flow

Decreasing late mortality among five-year survivors of cancer in childhood and adolescence: a population-based study in the Nordic countries

PURPOSE: To assess the risk of death in patients who survive more than 5 years after diagnosis of childhood cancer and to evaluate causes of death in fatal cases. PATIENTS AND METHODS: This was a population-based study in the five Nordic countries (Denmark, Finland, Iceland, Norway, and Sweden) using data of the nationwide cancer registries and the cause-of-death registries. The study cohort inclu

UNITE: a database providing web-based methods for the molecular identification of ectomycorrhizal fungi

Identification of ectomycorrhizal (ECM) fungi is often achieved through comparisons of ribosomal DNA internal transcribed spacer (ITS) sequences with accessioned sequences deposited in public databases. A major problem encountered is that annotation of the sequences in these databases is not always complete or trustworthy. In order to overcome this deficiency, we report on UNITE, an open-access da

Geomagnetic storm of 29-31 October 2003: Geomagnetically induced currents and their relation to problems in the Swedish high-voltage power transmission system

On 30 October 2003, an ongoing geomagnetic superstorm knocked down a part of the high- voltage power transmission system in southern Sweden. The blackout lasted for an hour and left about 50,000 customers without electricity. The incident was probably the most severe geomagnetically induced current ( GIC) failure observed since the well- known March 1989 Quebec blackout. The " three- phase'' storm

Candelariella (Candelariaceae) in western United States and northern Mexico: the species with biatorine apothecia

Three species of Candelariella in western North America, characterized by biatorine apothecia, are treated. Two new species are described, C. biatorina and C. lichenicola. Candelariella biatorina is a corticolous species growing in montane conifer forests in western North America. Candelariella lichenicola, described from northwestern Mexico, is a lichenicolous fungus that lacks an independent tha

How swifts control their glide performance with morphing wings

Gliding birds continually change the shape and size of their wings(1-6), presumably to exploit the profound effect of wing morphology on aerodynamic performance(7-9). That birds should adjust wing sweep to suit glide speed has been predicted qualitatively by analytical glide models(2,10), which extrapolated the wing's performance envelope from aerodynamic theory. Here we describe the aerodynamic a

Methods and uncertainties in bioclimatic envelope modelling under climate change

Potential impacts of projected climate change on biodiversity are often assessed using single-species bioclimatic 'envelope' models. Such models are a special case of species distribution models in which the current geographical distribution of species is related to climatic variables so to enable projections of distributions under future climate change scenarios. This work reviews a number of cri

Nomenclatural notes to Flora Nordica Vol. 6 (Thymelaeaceae-Apiaceae)

The following names in Flora Nordica Vol. 6 are subject to nomenclatural action: Helianthemum oelandicum var. canescens (typified), Epilobium hornemannii (typified), Oenothera nuda (validated), Myriophyllum spicatum (emendation of typification), Viola rupestris subsp. relicta (typified), Hippophae rhamnoides (typified), Angelica archangelica subsp. littoralis (typified). - Flora Nordica Note no. 3

Two-dimensional temperature measurements in flames using filtered Rayleigh scattering at 254 nm

Two-dimensional temperature measurements using filtered Rayleigh scattering (FRS) have been demonstrated. A tunable single-longitudinalmode alexandrite laser was employed to provide the tunable narrow-linewidth ultraviolet laser beam at 254 nm. Isotopic-enhanced mercury was utilized as an ultraviolet atomic filter. The strong absorption of the filter enabled effective suppression of elastic backgr

Atrial fibrillatory rate and risk of left atrial thrombus in atrial fibrillation.

ims In atrial fibrillation (AF), a relation between electrocardiogram (ECG) fibrillatory wave amplitude and thrombus formation has been sought for long with conflicting results. In contrast, the possible relation between atrial fibrillatory rate obtained from the surface ECG and left atrial thrombus formation in patients with AF is unknown and was consequently evaluated in this study. Methods and

Mechanisms of adaptation to nitrosative stress in Bacillus subtilis

Bacteria use a number of mechanisms for coping with the toxic effects exerted by nitric oxide (NO) and its derivatives. Here we show that the flavohemoglobin encoded by the hmp gene has a vital role in an adaptive response to protect the soil bacterium Bacillus subtilis from nitrosative stress. We further show that nitrosative stress induced by the nitrosonium cation donor sodium nitroprusside (SN

Aromatic interactions define the binding of the alphavirus spike to its nucleocapsid

Background: Most enveloped viruses bud from infected cells by a process in which viral intracellular core components interact with cytoplasmic domains of transmembrane spike glycoproteins. We have demonstrated previously that a tyrosine motif in the cytoplasmic domain of the Semliki Forest virus (SFV) spike glycoprotein E2 is absolutely essential for budding, In contrast, hardly anything is known

Binding of [3H]-5-hydroxytryptamine to human coronary artery and bypass graft vessels

OBJECTIVES: 5-Hydroxytryptamine (5-HT) has a wide range of vascular effects mediated via specific receptors and it has been suggested to be a mediator in ischemic heart disease. The aim of the present study was to localise the 5-HT receptors within the vessel wall. METHODS: Epicardial coronary arteries obtained from patients undergoing cardiac transplantation, internal mammary arteries from heart

Paternal alleles enhance female reproductive success in tropical pythons

The conventional view that female reproductive success is unlikely to benefit from multiple mating has come under strong challenge in recent years. In the present study, we demonstrate that the time wild-caught reproductive female water pythons (Liasis fuscus) spent in the laboratory prior to oviposition affected both hatching success and the number of male microsatellite alleles detected in the b