Background: Intraventricular hemorrhage (IVH) with post-hemorrhagic ventricular dilatation (PHVD) is a major cause of neurodevelopmental impairment and mortality in preterm infants. The mechanisms leading to PHVD and brain damage remain largely unknown. The choroid plexus and the ependyma, which constitute an essential part of the blood-brain barrier (BBB), are the first structures to encounter th

The paper presents a new thermochemical process for the production of isobutanol, which is an excellent biobased gasoline blendstock. The main feedstock for the process is glycerine, obtained as a byproduct in biodiesel production, being used together with methanol. The process was modeled in Aspen Plus. The process design is characterized by a high level of process integration, pinch analysis bei

Popular Abstract in Swedish Hos barn med cerebral pares (CP) spastisk diplegi är förhöjd muskelspänning s.k. spasticitet är ett vanligt symptom som påverkar kvalitén på rörelser. Muskler blir stela och förkortas och felställningar i leder kan uppstå. Selektiv Dorsal Rhizotomi (SDR) är ett ingrepp som används för att minska spasticitet i benen och som i kombination med sjukgymnastik kan ge beståendThe overall aim of the thesis was to describe long-term development of functional outcomes in children with cerebral palsy undergoing selective dorsal rhizotomy (SDR) combined with physiotherapy and to evaluate measures used in follow-up. Five years after SDR muscle tone was reduced, passive range of motion (PROM) increased in hip, knee and foot, gross motor function measured by the Gross Motor F

This article expands current acquisition literature to include sociocultural challenges on inter-organizational levels following acquisitions of young, innovative firms. Socioculture here denotes network parties' shared values, belief systems, and practices. Three acquisitions illustrate their consequences. The young, innovative firms and their acquirers are part of different networks, have dissim

Background: The thorough assessment of familial prostate cancer (PCa) risk is as important as ever to provide a basis for clinical counselling and screening recommendations. Objective: Our aim was to determine the age-specific risks of PCa and the risk of death from PCa according to the number and the age of affected first-degree relatives. Design, setting, and participants: The nationwide Swedish

In most tests of vocabulary size, knowledge is assessed through multiple-choice formats. Despite advantages such as ease of scoring, multiple-choice tests (MCT) are accompanied with problems. One of the more central issues has to do with guessing and the presence of other construct-irrelevant strategies that can lead to overestimation of scores. A further challenge when designing vocabulary size t

The risk of hip fracture rises rapidly with age, and is particularly high in women. This increase in fracture risk reflects both the age-related change in the risk of falling and decrements in the strength of the proximal femur. To better understand the extent to which proximal femoral density, structure and strength change with age as a function of gender, we have carried out a longitudinal analy

The analysis of annual extremes of hydrological and meteorological variables is frequently complicated by the presence of gaps in record, and when records are not only fragmented but also short, it is necessary to utilize to the full the information contained in them. One method is to abstract for statistical analysis all extreme events whose peaks exceed a pre-selected threshold value, but the th

The problem of fitting models to measured data has been studied extensively, not least in the field of computer vision. A central problem in this field is the difficulty in reliably find corresponding structures and points in different images, resulting in outlier data. This thesis presents theoretical results improving the understanding of the connection between model parameter estimation and pos

This paper describes the design of a robust PID controller for propofol infusion in children and presents the results of clinical evaluation of this closed-loop system during endoscopic investigations in children age 6y-17y. The controller design is based on a set of models that describes the inter- patient variability in the response to propofol infusion in the study population. The PID controlle

Evidence on associations between self-reported diabetes mellitus, diabetes duration, age at diabetes diagnosis, insulin treatment, and risk of biliary tract cancer (BTC) and hepatocellular carcinoma (HCC), independent of general and abdominal obesity is scarce. We conducted a prospective analysis in the EPIC-cohort study among 363 426 participants with self-reported diabetes data. Multivariable ad

Cohorts comprising fishermen's families on the east coast of Sweden have been found to have a high consumption of contaminated fish as well as high body burdens of persistent organochlorine pollutants (POPs). Their west coast correspondents are socio-economically similar, but with considerably lower POP exposure since the fish caught on the west coast is far less contaminated. The rationale for th

In order to preserve the variety of life on Earth, we must understand it better. Biodiversity research is at a pivotal point with research projects generating data at an ever increasing rate. Structuring, aggregating, linking and processing these data in a meaningful way is a major challenge. The systematic application of information management and engineering technologies in the study of biodiver

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Thylakoids are the photosynthetic membranes of the chloroplasts in green leaves. Thylakoids have been found to promote satiety when added to food, both in animal experimental models and in human. The thylakoids act through inhibition of lipase-colipase catalysed hydrolysis of triacylglycerol, which is the main dietary fat component. The mechanism for inhibition is either a binding of thylakoids to