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Knowledge-Based Industrial Robotics

When robots are working in dynamic environments, close to humans lacking extensive knowledge of robotics, there is a strong need to simplify the user interaction and make the system execute as autonomously as possible. For industrial robots working side-by-side with humans in manufacturing industry, AI systems are necessary to lower the demand on programming time and expertise. We are convinced th

Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA

The thiol-disulfide oxidoreductase ResA from Bacillus subtilis fulfils a reductive role in cytochrome c maturation. The pK(a) values for the CEPC (one-letter code) active-site cysteine residues of Ill are unusual for thioredoxin-like proteins ill that they are both high (> 8) and within 0.5 unit of each other. To determine the contribution of the inter-cysteine dipeptide of ResA to its redox and a

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

Comparison of horizontal and vertical advective CO2 fluxes at three forest sites

Extensive field measurements have been performed at three CarboEurope-Integrated Project forest sites with different topography (Renon/Ritten, Italian Alps, Italy; Wetzstein, Thuringia, Germany; Norunda, Uppland, Sweden) to evaluate the relevant terms of the carbon balance by measuring CO2 concentrations [CO2] and the wind field in a 3D multi-tower cube setup. The same experimental setup (geometry

The Negotiation of Collective Identities in German Cinema after Unification

This article analyses the negotiation of German identities in two films of the ‘newer German cinema’: Sonnenallee/Sun Alley (Haussmann 1999) and Schultze gets the blues (Schorr 2003). It argues that the former represents a defiant stance towards a dominant West German narrative which devalorizes the lived experiences of former GDR citizens. As a consequence, east and west are consolidated as relev

CaMKII inhibition with KN93 attenuates endothelin and serotonin receptor-mediated vasoconstriction and prevents subarachnoid hemorrhage-induced deficits in sensorimotor function.

It has been suggested that transcriptional upregulation of cerebral artery contractile endothelin (ETB) and 5-hydroxytryptamine (5-HT1B) receptors play an important role in the development of late cerebral ischemia and increased vasoconstriction after subarachnoid hemorrhage (SAH). We tested the hypothesis that inhibition of calcium calmodulin-dependent protein kinase II (CaMKII) may reduce cerebr

Har folk blivit ett pronomen? Utvecklingen av ordet folk under perioden 1300-2013

The Swedish word folk ('people') is normally considered an ordinary noun. This classification is, however, not completely unproblematic, since it is sometimes claimed that folk is actually undergoing a word-class change, becoming more and more pronoun-like. Similar changes from noun to generic pronoun are also attested for words with the meaning ‘people’ in other languages, making this a possible

Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities

In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha

The physico-chemical properties of dietary fibre determine metabolic responses, short-chain Fatty Acid profiles and gut microbiota composition in rats fed low- and high-fat diets.

The aim of this study was to investigate how physico-chemical properties of two dietary fibres, guar gum and pectin, affected weight gain, adiposity, lipid metabolism, short-chain fatty acid (SCFA) profiles and the gut microbiota in male Wistar rats fed either low- or high-fat diets for three weeks. Both pectin and guar gum reduced weight gain, adiposity, liver fat and blood glucose levels in rats

Bi-spectral beam extraction in combination with a focusing feeder

Bi-spectral beam extraction combines neutrons from two different kinds of moderators into one beamline, expanding the spectral range and thereby the utilization of an instrument. This idea can be realized by a mirror that reflects long wavelength neutrons from an off-axis colder moderator into a neutron guide aligned with another moderator emitting neutrons with shorter wavelengths which will be t

Exciton dynamics in alternating polyfluorene/fullerene blends

Exciton dynamics in alternating copolymer/fullerene solar cell blends have been investigated using femtosecond transient absorption spectroscopy. The acceptor concentrations have been varied over a wide range. Experimental data, kinetic modeling and simulations, all indicate that the efficiency of exciton conversion to charges is 100% even at acceptor concentrations as low as 20 wt%. The reported

Characterization of iron(III) in organic soils using extended X-ray absorption fine structure spectroscopy

The distribution of different iron (Fe) species in soils, sediments, and surface waters has a large influence on the mobility and availability of Fe, other nutrients, and potentially toxic trace elements. However, the knowledge about the specific forms of Fe that occurs in these systems is limited, especially regarding associations of Fe with natural organic matter (NOM). In this study, extended X

The Prognostic Significance of Tryptophanyl-tRNA Synthetase in Colorectal Cancer

Background: Tryptophanyl-tRNA synthetase (TrpRS) is an aminoacyl-tRNA synthetase involved in protein synthesis and regulation of RNA transcription and translation and is an inhibitor of angiogenesis. TrpRS has been shown to be differentially expressed in colorectal cancer (CRC) and has thus been identified as a potential prognostic marker. The aim of this study was to analyze the correlation of Tr

Controllable p-doping of graphene on Ir(111) by chlorination with FeCl(3).

The in situ chlorination of graphene on Ir(111) has been achieved by depositing FeCl(3) followed by its thermal decomposition on the surface into FeCl(2) and Cl. This process is accompanied by an intercalation of Cl under graphene and formation of an epitaxial FeCl(2) film on top, which can be removed upon further annealing. A pronounced hole doping of graphene has been observed as a consequence o

Pattern of Five-Year Weight Change by Age and Birth Cohorts in a Swedish Adult Population

The driving factors behind the global epidemic of obesity have not yet been fully elucidated. Investigating the effect of age and cohort on weight change might enable us to develop effective intervention strategies. Aims To analyse the pattern of BMI change by age and birth cohort over five-year follow-up in adult Swedish sample. Methods The data was drawn from the Scania Public Health Cohort. The

Influence of Ethanol on Lipid Membranes: From Lateral Pressure Profiles to Dynamics and Partitioning.

We have combined experiments with atomic-scale molecular dynamics simulations to consider the influence of ethanol on a variety of lipid membrane properties. We first employed isothermal titration calorimetry together with the solvent-null method to study the partitioning of ethanol molecules into saturated and unsaturated membrane systems. The results show that ethanol partitioning is considerabl

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Abstract in German Die Reaktionen auf die NS-Rassenpolitik in Schweden sind insofern besonders interessant, da Schweden weder besetzt, noch aliiert, noch kriegführend war. Die Folgen der deutschen Politik waren darum auf der einen Seite selbstverständlich viel indirekter als in den stärker unmittelbar berührten Staaten. Andererseits haben neueste Untersuchungen ergeben, dass viele Menschen auch im

Coding of procedures documented by general practitioners in Swedish primary care-an explorative study using two procedure coding systems

Background: Procedures documented by general practitioners in primary care have not been studied in relation to procedure coding systems. We aimed to describe procedures documented by Swedish general practitioners in electronic patient records and to compare them to the Swedish Classification of Health Interventions (KVA) and SNOMED CT. Methods: Procedures in 200 record entries were identified, co

Safety of thalidomide in newly diagnosed elderly myeloma patients: a meta-analysis of data from individual patients in six randomized trials

Treatment with melphalan-prednisone-thalidomide improves the outcome of patients with multiple myeloma and is now considered a standard of care for patients not eligible for transplantation. However, this treatment is a major source of morbidity. A meta-analysis of data from individual patients (n=1680) in six randomized trials was performed, comparing the effects of melphalan-prednisone-thalidomi