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No hypoperfusion is produced in the epicardium during application of myocardial topical negative pressure in a porcine model.

ABSTRACT: BACKGROUND: Topical negative pressure (TNP), commonly used in wound therapy, has been shown to increase blood flow and stimulate angiogenesis in skeletal muscle. We have previously shown that a myocardial TNP of -50 mmHg significantly increases microvascular blood flow in the myocardium. When TPN is used in wound therapy (on skeletal and subcutaneous tissue) a zone of relative hypoperfus

Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness: Main results from the Beta-Blocker Cholesterol-Lowering Asymptomatic Plaque Study (BCAPS)

BACKGROUND: Statins reduce cardiovascular events and progression of carotid intima-media thickness (IMT). beta-Blockers are also known to reduce cardiovascular events, but less is known about their effects on carotid IMT. METHODS AND RESULTS: We conducted a randomized, double-blind, placebo-controlled, single-center trial to compare the effects of low-dose metoprolol CR/XL (25 mg once daily) and f

The Cromer blood group system: a review

The antigens of the Cromer blood group system reside on decay accelerating factor (DAF), a protein belonging to the regulators of complement activation family. The blood group system consists of eight high-incidence antigens and three low-incidence antigens. The molecular basis for the antigens is known and, with the exception of IFC, each antigen is the product of a single nucleotide polymorphism

Quality assurance of patient dosimetry in boron neutron capture therapy

The verification of the correctness of planned and executed treatments is imperative for safety in radiotherapy. The purpose of the present work is to describe and evaluate the quality assurance (QA) procedures for patient dosimetry implemented at the boron neutron capture therapy (BNCT) facility at Studsvik, Sweden. The dosimetric complexity of the mixed neutron-photon field during BNCT suggests

Strategisk förändring, makt och kunskap : om disciplinering och motstånd i tidningsföretag

Popular Abstract in Swedish Studien beskriver och analyserar strategisk förändring i tre svenska tidningsföretag. I studien beskrivs hur företagen utvecklades från enaffärs-verksamheter till multiaffärs-verksamheter. Studien pekar på hur denna utveckling framförallt ska ses som resultat av etableringen och spridningen av en ny kunskapsformation. Ett centralt innehåll i den kunskapsformationen var The dissertation examines power and knowledge in strategic changes. It is a study of changes in three Swedish newspaper companies which developed from single-business to multi-business corporations. It is suggested that this transformation was based upon the establishment and reproduction of a new knowledge formation. This knowledge was the knowledge of strategy, particularly the classical perspec

Behaviour-focused pain coping: consistency and convergence to work capability of the swedish version of the chronic pain coping inventory.

The aim was to study the psychometric properties of the Swedish version of the Chronic Pain Coping Inventory. The material consisted of a group of 100 subjects recruited from a large population study. Pain status and the absence of pain-related sick leave during the previous year conditioned inclusion. Another group comprised 160 patients on the long-term sick list and who had been referred to a m

Carotenoid and pheophytin on semiconductor surface: Self-assembly and photoinduced electron transfer

Self-assembling of a carotenoid and pheophytin a into a supramolecular system was observed on the surface of nanocrystalline TiO2, and the photoinduced electron-transfer reactions within the system were studied by means of femtosecond transient absorption and laser flash photolysis techniques. Excitation of the pheophytin moiety results in ultrafast electron transfer from carotenoid to the excited

Telomerase in yeast

The ribonucleoprotein enzyme telomerase synthesizes telomeric DNA by copying an internal RNA template sequence. The telomerase activities of the yeasts Saccharomyces castellii and Saccharomyces cerevisiae-with regular and irregular telomeric sequences, respectively-have now been identified and characterized. The S. cerevisiae activity required the telomerase RNA gene TLC1 but not the EST1 gene, bo

Monochromatic phototherapy in elderly patients: A new way of treating chronic pressure ulcers?

Background and aims: Monochromatic pulsating light may have effects of importance for wound healing, and promising results were obtained in an open study on the healing of pressure ulcers, which motivated the present study. Methods: One hundred and sixty-four in- and outpatients with grade II and III ulcers were treated with monochromatic pulsating light or placebo over the ulcerated area, accordi

Computational strategies in flame-spread modelling involving wooden surfaces

Various approaches to flame-spread and fire-growth modelling are discussed and are evaluated using experimental results from different tests. Use of Computational Fluid Dynamics, CFD, in fire modelling is discussed and the performance of different CFD codes in wall flow modelling is analysed. Different pyrolysis models are discussed with respect to their major assumptions and the input data requir

Expression of platelet-derived growth factor-beta receptors on human fibroblasts. Regulation by recombinant platelet-derived growth factor-BB, IL-1, and tumor necrosis factor-alpha

Stimulation of human fibroblasts by platelet-derived growth factor (PDGF)-BB leads to a down-regulation of PDGF beta-receptors and a concomitant appearance of intracellular granular accumulations of receptors, as determined by stainings with the mAb PDGFR-B2. The granules contained both the ligand and PDGF beta-receptors, as revealed by double-immunofluorescence staining, and were formed in respon

Dietary fibre in fermented oat and barley beta-glucan rich concentrates

The ability of different lactic acid bacteria to influence the physicochemical characteristics (content, viscosity and molecular weight) of dietary fibre in beta-glucan-rich barley and oat concentrates was investigated. The cultures used were Lactobacillus acidophilus and the exopolysaccharide producing strain Pediococcus damnosus 2.6, together with the yoghurt culture, V2 (a mixture (1:1) of Lact

Microwave detection at 110 GHz by nanowires with broken symmetry

By using arrays of nanowires with intentionally broken symmetry, we were able to detect microwaves up to 110 GHz at room temperature. This is, to the best of our knowledge, the highest speed that has been demonstrated in different types of novel electronic nanostructures to date. Our experiments showed a rather stable detection sensitivity over a broad frequency range from 100 MHz to 110 GHz. The