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Men’s Experience of Abuse During Child- and Adulthood and Identification of Self as Perpetrator : A Cross-Sectional Study in Psychiatric Care

The aim of this study was to describe the extent to which men in psychiatric care have experienced emotional, physical, and sexual abuse during the life course and the association between this experience and being a perpetrator oneself. The aim was also to identify who exposed them to abuse and whether there was an association between the category of abuser and being a perpetrator oneself. A cross

Svårfångad lundaalumn kämpade för Ukraina

Kort biografisk artikel om kosackhetmanssonen, diplomaten, militären m m Georg Orlik (1702-1759) med tonvikt på dokumentationen kring dennes tid som student vid Lunds universitet.

Prediction of amyloid and tau brain deposition and cognitive decline in people with Down syndrome using plasma biomarkers : a longitudinal cohort study

BACKGROUND: Plasma biomarkers associated with Alzheimer's disease could improve prognostic assessment for people with Down syndrome in both clinical practice and research settings. We aimed to identify the plasma biomarkers that most accurately predict longitudinal changes in Alzheimer's disease-related pathology and cognitive functioning in individuals with Down syndrome.METHODS: This longitudina

Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies

BACKGROUND: Melanoma, the deadliest form of skin cancer, exhibits resistance to conventional therapies, particularly in advanced and metastatic stages. Mitochondrial pathways, including oxidative phosphorylation and mitochondrial translation, have emerged as critical drivers of melanoma progression and therapy resistance. This study investigates the mitochondrial proteome in melanoma to uncover no

Apathy and affective symptoms associated with elevated plasma neurofilament light but not p-tau181 in Alzheimer's disease

INTRODUCTION: Apathy and affective neuropsychiatric symptoms (NPS) are prevalent in Alzheimer's disease (AD), yet their neurobiological cause is still unclear. We examined associations between plasma neurofilament light chain (NfL) and tau pathology (p-tau181) with apathy and affective symptoms in mild cognitive impairment (MCI) and AD dementia. METHODS: This longitudinal study analyzed data from

Using Compression Stockings to Prevent Recurrence of Vasovagal Syncope : A Randomized Sham-Controlled Trial

Background: Vasovagal syncope (VVS) is a common yet challenging condition with limited effective treatments. Elastic compression stockings (ECS) have been proposed as a potential therapy, but their real-world effectiveness remains unclear. Objectives: This study sought to compare the effectiveness of lower extremity compression with thigh-high ECS vs sham stockings for the prevention of VVS recurr

Multilevel small-area childhood stunting risk estimation: Insights from spatial ensemble learning, agro-ecological and environmentally remotely sensed indicators

Small area childhood stunting risk estimations remain a critical tool for shaping the surveillance policies of such a public health concern. With classical statistical methods, stunting risk metrics are mainly reported at a national level, which inhibits fine-scale insights at a more localized level. To this end, we implemented a novel multilevel small area estimation (SAE) approach for effectivel

Linear Regulator-based synchronization of positive discrete-time multi-agent systems

A fundamental challenge in control theory is designing protocols that achieve synchronization in interconnected systems. This paper addresses positive synchronization on undirected graphs for homogeneous discrete-time positive systems. It introduces a static feedback protocol derived from the Linear Regulator problem, where the stabilizing policy is determined by solving an algebraic equation usin

From Social Hubs to Silent Shops: The Impact of Unmanned Stores on Rural Community Life

This study explores how the emergence of unmanned stores impacts the sense of community in rural areas. It is set against the backdrop of increased urbanization, which threatens the survival of smaller rural communities. We study this through ethnographic inquiry into the emergence of unmanned stores. These have been introduced to counteract the depopulation of rural areas. We identify four ways i

Bystander behavior in workplace bullying : a vignette study exploring how organizational space and situational strength influence intentions to intervene

Purpose: The study explores how organizational space and situational strength influence bystanders’ intentions to intervene in workplace bullying within the healthcare sector. Design/methodology/approach: The research employs vignette-based interviews with 24 healthcare professionals from various medical fields in Sweden. The vignettes depict different bullying scenarios occurring in various spati

A multi-scaling approach showing a transient metabolic mismatch in a freshwater fish (Zingel asper) during an acute heat stress

Heat stress events will be more frequent and intense in the future. These events will challenge the capacity of organisms to exhibit sufficient metabolic flexibility to adapt to such variations. To better understand the acclimation processes implemented in response to acute warming, with an integrative approach we examined in vivo metabolic rate and cardiac mitochondrial respiration in the Rhône s

Integrative taxonomy, phylogeny and distribution patterns of the diverse Neotropical cloud forest butterfly genus Perisama Doubleday (Nymphalidae, Biblidinae, Callicorini)

Phylogenetic relationships of the predominantly Andean species-rich nymphalid genus Perisama are explored based on five genetic markers and a total of 3719 bps, and morphological characters of the adults with an emphasis on male genitalia and wing colour patterns. Its monophyly is recovered by including the genera Orophila, which turns out polyphyletic, and Mesotaenia. Two main, highly supported c

Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury

White matter (WM) disruption and atrophy is a consequence of traumatic brain injury (TBI) and contributes to persisting cognitive impairment. An increased expression of the myelin-associated axonal outgrowth inhibitor Nogo-A and oligodendrocyte pathology might be negatively associated with postinjury WM changes. Here, we analyzed brain tissue from severe TBI patients, obtained by surgical decompre