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Characterization of two novel cutaneous human papillomaviruses, HPV93 and HPV96.

Two novel human papillomaviruses (HPVs), HPV93 and HPV96, with genomes of 7450 and 7438 bp, respectively, are described. The Ll open reading frame of HPV93 showed highest identity to HPV24 (79%) and that of HPV96 had highest identity to HPV92 (71 %). Real-time PCR for HPV92, 93 and 96 on stripped biopsies from tumours and healthy skin from 269 immunocompetent patients found HPV DNA in 2.6 % of tum

Geography and geometry of pre-Caledonian western Baltica: U-Pb geochronology and Palaeomagnetism

Popular Abstract in Swedish Den kontinent Skandinavien idag tillhör kallas Eurasia, men den kontinent vi ser idag har inte alltid funnits. Kontinenterna var inte bara sammanfogade på andra sätt, de har också rört sig över jordens yta (de långsamma med samma hastighet som naglar växer!), i platt-tektoniska processer. Innan uppkomsten av Eurasia har Skandinavien i omgångar tillhört andra konstellatiIn an attempt to reconstruct the pre-Caledonian cratonic margin of Fennoscandia, U-Pb geochronological and geochemical investigations have been performed on allochthonous orthogneisses in the northern Swedish Caledonides. The crystalline basement of the nappes have also been examined to further constrain the continuation of various chronologically defined orogenic belts. To constrain the global pa

Tumor specific VEGF-A and VEGFR2/KDR protein are co-expressed in breast cancer

Angiogenesis is a prognostic indicator in primary breast cancer regulated by specific angiogenic factors and their receptors. Vascular endothelial growth factor-A (VEGF-A), so far considered the most important, acts through dimerization of the receptor VEGFR2/KDR within the receptor tyrosine kinase family of VEGF receptors. In order to study the interplay between VEGF-A and VEGFR2/KDR in breast ca

Skalmurskonstruktionens fukt- och temperaturbetingelser

I rapporten beskrivs byggnadsfysikaliska mätningar i ett provhus med olika skalmurskonstruktioner. Mätningar har pågått under en 3-årsperiod och främst varit inriktade på fukt- och temperaturbetingelser i murverket, luftspalten, isoleringen och träreglarna.

Mortality and causes of death in a Swedish series of systemic sclerosis patients

OBJECTIVES: To analyse survival rates and the causes of death in a systemic sclerosis (SSc) population, and to evaluate the occurrence of fatal malignant neoplasms and their possible association with oral cyclophosphamide (CYC) treatment. METHODS: Survival was calculated for 249 SSc patients followed up for up to 13 years. Mean (SD) follow up was 5.8 (4.2) years. The 49 decreased patients were sub

R-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion

Pancreatic islets have a central role in blood glucose homeostasis. In addition to insulin-producing beta-cells and glucagon-secreting alpha-cells, the islets contain somatostatin-releasing delta-cells(1). Somatostatin is a powerful inhibitor of insulin and glucagon secretion(2). It is normally secreted in response to glucose(3) and there is evidence suggesting its release becomes perturbed in dia

Safety Politics and Risk Perceptions in Malaysian Industry

The thesis concerns risk and safety in manufacturing companies in a developing country. Risk and safety is viewed as integral to the social relations between management and labour. The Malaysian case presents a historical conjuncture of this conflict theme, which is very different from that of its Western genesis. On this basis, the primary objective of the thesis is defined as an effort to escape

On the formation of extreme-ultraviolet helium lines in the Sun: Analysis of SOHO data

The resonance lines of helium in the Sun are several times stronger than expected, relative to lines of other ions. To explore the origins of this "helium enhancement,'' we have studied data from the SUMER, CDS, MDI, and EIT instruments on the Solar and Heliospheric Observatory (SOHO). Time series data obtained in a quiet region and a coronal hole indicate that the spatio-temporal properties of th

Wireless esophageal PH monitoring. Clinical evaluation of a new technique

Popular Abstract in Swedish Gastroesofageal refluxsjukdom innebär att maginnehåll backar (reflux) upp från magsäcken till matstrupen på ett onormalt sätt. Hos den friska individen finns flera mekanismer som skyddar matstrupen från reflux, vilket tydligt åskådliggörs av att man efter en måltid kan ställa sig upp och ner utan att föda backar upp i matstrupen. Vid refluxsjukdom föreligger defekter inEsophageal pH monitoring is important in the clinical management of patients with symptoms suggestive of gastroesophageal reflux disease (GERD), and in research aiming to clarify the mechanisms involved in the development of GERD complications. Catheter-based techniques for pH recording are uncomfortable, not well tolerated by all patients and cannot reliably measure acid exposure in the most dist