Sökresultat

Populärvetenskaplig sammanfattning Det finns två huvudsakliga typer av diabetes, typ 1 (T1D) och typ 2 (T2D), samt flertalet mindre vanliga former av diabetes t.ex. MODY. I bukspottkörtelns β-celler produceras insulin, vilket är det mest centrala hormonet i regleringen av blodsockret som verkar genom att öka cellernas upptag av socker från blodet. T2D, tidigare kallad åldersdiabetes, beror till sABSTRACT The prevalence of diabetes keeps increasing around the world, of which type 2 diabetes (T2D) accounts for 90%. Both lifestyle and genetic factors contribute to pathogenesis of the disease. A significant proportion of the basic research on T2D focuses on the genetic components and susceptibility genes especially on the insulin secretion. Herein, we functionally examined 4 T2D candidate ge

En ökande trend av tvärvetenskapliga forskningsprojekt har gett upphov till en uppsjö litteratur i ämnet. Denna försöker på olika vis belysa problem som kan uppstå vi denna typ av samarbeten och ger mer eller mindre handfasta förslag på hur dessa på ett effektivt vis kan överbryggas och medvetandegöras. Förvånansvärt lite utrymme lämnas åt fördelarna med tvärvetenskapligt arbete. Vad är det som dr

Abstract Failures in achieving the 2010 goals of slowing down or halting the loss of biodiversity, and the setting of new biodiversity targets set for 2020, stress an urgent need to expand current reserve networks and to improve their effectiveness in protecting species and habitats. Habitat suitability models, and derived maps from them, are among the broadest used tools for identifying the ecol

Populärvetenskaplig sammanfattning Strukturbioinformatik och datorgrafik Proteiner bygger upp våra muskler, hud, hår m.m. och fungerar som katalysatorer (enzymer) för reaktioner som behövs för livet. Våra gener kodar för proteiner som utför funktioner i kroppen. Bioinformatik handlar om att studera det genetiska materialet hos människor och andra organismer. Strukturbioinformatik riktar in sig Abstract This Master Thesis explores a variety of approaches to protein structure comparision : CLICK, BetaSuperPoser, MAMMOTH, Minkowski Sum Boundary Calculation, 3DSurfer / Zernike Descriptors, Spherical Harmonics, D2 Shape (distance histogram) and ProBiS. The methods are categorized according to how they function and the meaning of their output parameters, in particular RMSD, is discussed. We

The purpose of this work is to give an insight into how vocal students describe their desire to sing and practice singing, and to find out what the students get feedback from their surroundings in voice and in practice and how feedback affects them. The study would thus create an understanding of what motivates students to sing and practice singing. The study is based on qualitative interviews wit

Creating a musical – Participants’ experiences of the Lovewell Institute’s creative process This study utilizes qualitative research methods in order to explore the experiences of students who participated in Lovewell Institute’s creative musical theatre workshop in Oskarshamn, Sweden 2012. The two main methods used are participative observation of the workshop and interviews with five of the stud

The study is based on semi-structured interviews with two music teachers, one at the elementary and high school Sankt Annæ Gymnasium (Copenhagen) and one at the elementary and high school Adolf Fredriks musikklasser (Stockholm). By asking more or less identical questions to both of them I could clearly see the differences between the two schools. At Sankt Annæ boys and girls have separate teaching

Internet fraud has in Sweden become a growing problem the last decade for people who want to sell and buy belongings through the Internet. This type of market is worth 212 billion swedish crones in year 2010 and it’s increasing. In our paper we intend to explain why people commit internet fraud, we want to explain how human act by applying Webers thoughts and Sykes and Matzas techniques of neutral

Denna studie syftar till att undersöka förändringen av den psykiska hälsan hos en grupp manliga flyktingar. Skattningarna är utförda före och efter stabiliserande/inledande gruppbehandling utförd vid Röda Korsets behandlingscenter för krigsskadade och torterade i Malmö. Validerade och välkända självskattningsverktyg avseende posttraumatiskt stressyndrom (PTSD), depression och ångest har använts. SThis study aims to investigate changes in mental health of a group of male refugees. The estimates are done before and after initial stabilization treatment, performed at the Red Cross treatment center for war wounded and tortured in Malmö. Validated and well-known self-assessment tool for post-traumatic stress disorder (PTSD), depression and anxiety have been used. The estimates are made on three

Syfte: Syftet med uppsatsen är att undersöka förekomsten av avkastningsmönster i historiska aktieindex hämtade från Affärsvärlden. Uppsatsen skall även studera eventuella mönsters skillnader mellan olika branscher. Metod: Studien har utgått från den deduktiva ansatsen, dvs. från teori formas en hypotes som testas via t.ex. analys av data. Från denna analys dras sedan en slutsats som leder till en

In the past, symmetric communication in customer relationships was seen as utopian, today, however, social media have provided new tools which create new dimensions of possibilities for dialogue. Today we find ways through social media to create a more symmetric communication between customer and organization. This study analyzes how three organizations within the sporting and outdoors branch comm

Measuring results and outcome in social work: A casestudy on the application of the outcome measurement tool Forandringskompasset in the homelessness services in the municipality of Copenhagen [translated title] The aim of this study was to examine how New Public Management inspired outcome measurement tools is applied and understood by respectively the administrative management and the professio

I den här uppsatsen undersöks vad som bestämmer priset på den svenska fjärrvärmemarknaden. Spelreglerna på den svenska fjärrvärmemarknaden har förändrats över tiden och efter elmarknadsreformen 1996 ska fjärrvärmeföretag drivas på affärsmässiga grunder. Detta har aktualiserat frågan om fjärrvärmeföretagen tar ut oskäliga priser. Den modell som används för att undersöka vad som bestämmer priset tar

Within an extensive research project known as the EuroVaQ project, data on European individuals’ WTP for health was collected through survey methods. This thesis uses data from the EuroVaQ project in order to estimate the WTP per QALY Sweden. The major finding of the study is that the mean value is estimated to SEK 485 685. Furthermore, WTP is positively associated with age and income of the respo

International courts have relied on article 31(3)(c) of the Vienna Convention on the Law of Treaties, which is an inherent element of the general rule of interpretation, more and more frequently in the recent years. The chief aim of this Master thesis is to determine the significance that the European Court of Human Rights gives to it. At the outset, the meaning of article 31(3)(c) is explained.

På grund av den ökande förekomsten av fetma och fetmarelaterade sjukdomar, såsom diabetes och förfettning av levern, har intresset för olika diagnostiseringsmetoder av dessa sjukdomar också ökat de senaste åren. Då man dessutom har upptäckt att det finns en relation mellan sjukdom och fettsammansättningen (mättat, enkelomättat och fleromättat fett) i exempelvis levern, har intresset för att kunna The increasing prevalence of obesity and obesity related diseases in this modern world has resulted in a lot of research in the area of water-fat separation with magnetic resonance imaging (MRI). Since the introduction of the two-point Dixon technique, this area of research has expanded and relationships have been discovered between fat content and fatty acid (FA) composition, and diseases such as

The tendential fall in the rate of profit lies in the center of a long-lasting debate among Marxist scholarship on its centrality and empirical relevance in the investigation of structural crises. Without neglecting the financial aspect of the current crisis, which is covered in the vast majority of academic accounts, we try to discover its underlying roots in the entire spectrum of capitalist pro

What are the motives that drive Chinese investments into European Union? And even more, what determines the location choice? These are questions to which the paper seeks to find an answer to by conducting an empirical analysis with the use of panel data regression. Having most of Chinese investment flowing in only few Western European countries it is important to observe what determines the locati

The thesis examines to what extent dominant undertakings, within the evolving technology industry, are considered to use an anti-competitive conduct when strategically combining technical tying and different patent combinations. Such conduct may result in leveraging a position from one product market to another, leading to evergreening and possible abuse of such dominant position, in accordance to

Trots att pensionssystem ökar den ekonomiska statusen bland äldre, ger upphov till omfördelningar mellan olika inkomstgrupper samt bidrar till en reducerad fattigdomsnivå är dess utbredning fortsatt begränsad i Afrika söder om Sahara. Uppsatsen syftar därmed till att undersöka vilka faktorer som har betydelse för förekomsten av pensionssystem i regionen. Tidigare kolonial tillhörighet, utbredninge