Fast method to find sterically possible amino acid substitutions
With the growing pool of deposited protein structures, the need for structural analysis tools grows. In study of amino acid substitutions the variety of analysis tools is high; nevertheless, there is a lack of programs serving specific purpose, such as identifying if an amino acid substitution would cause a clash in the structure or not, given just the structure of the original protein. In this stAnalysing structural damage caused by changes in proteins In an organism, even only one single change of an amino acid can sometimes lead to disease, if the protein is a part of an important biological function. Because of that, it is important to study those changes and be able to predict if an amino acid substitution would cause harm. There are various ways a substitution can be harmful to a pr