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Virtual clinical trials (VCTs) have been used widely to evaluate digital breast tomosynthesis (DBT) systems. VCTs require realistic simulations of the breast anatomy (phantoms) to characterize lesions and to estimate risk of masking cancers. This study introduces the use of Perlin-based phantoms to optimize the acquisition geometry of a novel DBT prototype. These phantoms were developed using a GP
Background: Exposure to many contacts is the main risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, while risk of serious disease and death is chiefly determined by old age and comorbidities. Relative and population-attributable fractions (PAFs) of multiple medical and social exposures for COVID-19 outcomes have not been evaluated among older adults. Objective
Introduction: Platelet function tests are used to screen and diagnose patients with possible inherited platelet function defects (IPFD). Some acquired platelet dysfunction may be caused by certain drugs or comorbidities, which need to be excluded before testing. Aims: To identify current practice among centres performing platelet function tests in Northern Europe. Methods: A total of 14 clinical c
Background: Hypotension is common after cardiac arrest (CA), and current guidelines recommend using vasopressors to target mean arterial blood pressure (MAP) higher than 65 mmHg. Pilot trials have compared higher and lower MAP targets. We will review the evidence on whether higher MAP improves outcome after cardiac arrest. Methods: This systematic review and meta-analysis will be conducted based o
Most countries in Sub-Saharan Africa have made great strides towards more accessible and higher quality schooling and medical systems in recent years. Despite this, education and health care in Africa lag behind other developing regions and large inequalities in educational levels and health care access remain across countries, subnational regions, and gender. Cameroon, in west-central Africa, wit
Objective: Extended anticoagulation therapy should always be considered after standard treatment of an unprovoked episode of venous thromboembolism (VTE). It can also be considered for selected patients with provoked VTE. However, the evidence-based protocols suggested by some clinical guidelines and risk assessment tools to guide this practice are limited and ambiguous. The goal of the present su
Background: Previously, we investigated tonsillar carriage of Fusobacterium necrophorum by PCR and found a high tonsillar carriage rate (21%) in asymptomatic 15-25year olds, but the same age group is most commonly affected by severe F. necrophorum infections. Interestingly, we found Cycle threshold (Ct)-values in asymptomaticcarriers to be high (median 29). Possibly, the Ct-value could differentia
Att använda teori är en viktig del av historievetenskaperna. Med hjälp av teori kan en analys fördjupas och de empiriska resultaten göras greppbara i ett vidare sammanhang. För den som ska skriva en uppsats kan dock arbetet med teori framstå som abstrakt. Hur kan teorier bidra till historiska undersökningar? Hur arbetar man med teori – i praktiken? Det är temat i denna bok.Bokens kapitel tar avsta
Background: Short blood culture time-to-positivity (TTP) has been shown to correlate with infective endocarditis, yet TTP has never been investigated in Fusobacterium necrophorum bacteremia. Since Lemierre’s syndrome occurs after an oropharyngeal infection with the development and subsequent embolization of septic thrombophlebitis of the internal jugular vein, it could also be considered an endova
Background: Previously, we investigated tonsillar carriage of Fusobacterium necrophorum by PCR and found a high tonsillar carriage rate (21%) in asymptomatic 15-25 year olds, but the same age group is most commonly affected by severe F. necrophorum infections. Interestingly, we found Cycle threshold (Ct)-values in asymptomatic carriers to be high (median 29). Possibly, the Ct-value could different
Previous research suggests that parties in contractual relationships adopt a governance structure that economizes on transaction costs, and then over time learn to govern the contractual relationships in a more efficient manner by incrementally aligning contractual terms with transaction attributes based on new experiences made in the relationship. This implies that learning to contract and the de
European Spallation Source ERIC (ESS ERIC) is a legal entity established by the European Commission based on a European Union regulation (the ERIC Regulation). It is co-hosted by Sweden and Denmark and has its statutory seat in Lund, Sweden. This means that, according to the ERIC Regulation, ESS ERIC is a legal subject of both EU law and Swedish national law. In terms of hierarchical interplay bet
Morpho-taxonomic studies of cetrarioid lichens from India recorded 46 species representing Cetraria, Melanelia, Nephromopsis, and Platismatia. Nephromopsis awasthii is described as new to science; and Cetraria endochrysea, C. sinensis, Melanelia agnata, Nephromopsis ciliaris, N. morrisonicola, N. pseudocomplicata, N. pseudoweberi, N. rugosa, N. weii, and N. yunnanensis are reported for the first tMorpho-taxonomic studies of cetrarioid lichens from India recorded 46 species representing Cetraria, Melanelia, Nephromopsis, and Platismatia. Nephromopsis awasthii is described as new to science; and Cetraria endochrysea, C. sinensis, Melanelia agnata, Nephromopsis ciliaris, N. morrisonicola, N. pseudocomplicata, N. pseudoweberi, N. rugosa, N. weii, and N. yunnanensis are reported for the first t
This paper analyzes strategies that can be successfully pursued to implement measures to reduce car traffic in what has traditionally been a very car-centric planning praxis. Analytically, the paper use path dependency theory to provide an understanding of why certain types of measure are not implemented in cities on as widespread a basis as policy objectives may require, and to understand how tra
The objective of the paper is to explore whether particular problematisations of cars and car use lead to sets of solutions that may not deal with all problems associated with car use, and whether this leads to any internal conflicts within the chosen policies. The paper is based on a review of local transport policy documents from 13 cities in four countries using the lens of policy problematisat
