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A fundamental challenge in medical microbiology is to characterize the dynamic protein-protein interaction networks formed at the host-pathogen interface. Here, we generate a quantitative interaction map between the significant human pathogen, Streptococcus pyogenes, and proteins from human saliva and plasma obtained via complementary affinity-purification and bacterial-surface centered enrichment

This book offers an in-depth and critical analysis of the Istanbul Convention, along with discussions on its impact and implications.The work highlights the place of the Convention in the landscape of international law and policies on violence against women and equality. The authors argue that the Convention with its emphasis on integrated and comprehensive policies has an important role in promot

Article 5 of the Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence (the Istanbul Convention) enshrines the standard of due diligence to frame states’ obligations. In the existing literature in the area of violence against women, the standard of due diligence has been uncritically endorsed; the reason being that it has played a crucial role in the

The European Court of Human Rights has consistently reiterated that positive obligations under the European Convention on Human Rights arise when state authorities knew or ought to have known about risk of harm. This article attempts to describe and assess the role of state knowledge in the framework of positive obligations, and to situate the Court’s approach to knowledge about risk within an int

BACKGROUND: Oxidative stress may be involved in the aetiology of inflammatory bowel disease and whether dietary polyphenols, which possess antioxidants properties, prevent its development is unknown.METHODS: A total of 401,326 men and women aged 20 to 80 years from 8 countries were recruited between 1991 and 1998 and at baseline completed validated food frequency questionnaires. Dietary polyphenol

Gender influences how researchers engage with the field (Porter & Schänzel, 2018). Departing from this proposition, this chapter offers reflections on gender from masculine vantages in the context of a qualitative research project investigating tourism enterprising in southern Sweden. Tourism enterprising is an important aspect of tourism development. Focusing on personal experiences associate

In this chapter we ask if mass tourism, morphing into over-tourism, can be conceptualised as an emerging plague of zombie tourists, and what kinds of tourism futures might come of it? Overtourism is not only unsustainable; it is the logical outcome of capitalism and thus, a token signifying that the capitalist system is well and alive even though it is threatening everything else on Earth. We outl

A growing literature (i.e. Jaffee, Lynch, Richardson, and Van Nieuwerburgh 2009, Acharya and Schnabl 2009) argues that securitization improves financial stability if the securitized assets are held by capital market participants, rather than financial intermediaries. I construct a quantitative macroeconomic model with a novel specification for mortgage-backed securities (MBS) to evaluate this clai

A high-resolution alpha, electron, X-ray and gamma-ray coincidence experiment was conducted at the GSI Helmholtzzentrum für Schwerionenforschung GmbH in Darmstadt, Germany. It aimed to identify and study alpha-decay chains of isotopes of element Z=115. Experimental data, including the 30 identified chains, were analyzed self-consistently with a virtually constructed spectroscopic set-up using GEAN

Purpose: The purpose of this paper is to investigate how grocery retailers configure their online fulfilment centres (OFC) as they move towards an omni-channel structure and what contextual factors influence their decisions. Design/methodology/approach: An exploratory case study with three grocery retailers in the Nordic countries was conducted. The study investigates the current OFC configuration

Incentive alignment is discussed as one of the key factors for successful implementation of supply chain management. However, there is a lack of empirical research regarding implementation as well as evaluation of the effects of alignment mechanisms in practice. The purpose of this study is therefore to explore and describe the current practice and to identify gaps of Supply chain incentive alignm

The future role of the town center as a retail hub is uncertain. Despite being a historical meeting place, town centers have been struggling for decades to attract customers and retain retailers after the development of out-of-town centers and advancement of online shopping. Previous retail research has mostly used rational explanations and strategies like improved access, pricing, and retail mix

Dupuytren's disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Generally, treatment has been up against a high frequency of complications and recurrence, but promising results are reported from less invasive tr

PurposeThe purpose of this study is to understand current trends and challenges in omnichannel logistics.Based on the study findings, a number of propositions are formulated.Design/methodology/approachAn exploratorysurvey study is conducted with 28Swedish retail companies that are involved with or plan to engage in omnichannel logistics. The study investigates the retailers’ previous andcurrent si