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An indication for deconfinement in Au plus Au collisions at RHIC

We present simultaneous, quality fits to final BRAHMS, PHOBOS, STAR and PHENIX data on particle spectra and two-particle Bose-Einstein or HBT correlations as measured in Au+Au collisions at root(S)NN = 130 GeV. Using the Buda-Lund hydro model, the best fit is achieved when the most central 1/8th of the particle emitting volume is superheated to T > T-c = 170 MeV. In contrast, we find no indication

201Thallium SPECT and 1H-MRS compared with MRI in chemotherapy monitoring of high-grade malignant astrocytomas

PURPOSE: To compare chemotherapy treatment monitoring in astrocytoma by 201thallium single photon emission computed tomography (SPECT) and photon magnetic resonance spectroscopy (1H-MRS) with magnetic resonance imaging (MRI), and to evaluate the influence of morphological tumor changes on cerebral 201thallium uptake and metabolic changes in 1H-MRS. MATERIALS AND METHODS: Six patients with highly m

ECONOMIC AND SOCIAL CRISES IN SIERRA LEONE : The Role of Small-scale Entrepreneurs in Petty Trading as a Strategy for Survival 1960-1996

Popular Abstract in Swedish Målsättningen med avhandlingen är att analysera vilken roll småskaligt entreprenörskap som alternativ överlevnadsstrategi har spelat i Sierra Leone under den ekonomiska kris som drabbade landet efter självständighet på 1960-talet. Avhandlingen baseras på nätverksteori, snowball metod och det empiriska underlaget utgörs av en studie av utvecklingen i Sierra Leone, med avSierra Leone is a small country with rich mineral resources such as diamonds, bauxite, gold and iron ore. Other resources include fishing, forestry and fertile agricultural land, which enable people to farm without any sophisticated methods of mechanization. Nevertheless, with all its wealth in resources, the country is relatively poor and is one of the least developed countries in the Sub-Saharan

Effects of pH, salt and time on ligand binding properties of overexpressed melanocortin 4 receptor.

The G-protein coupled melanocortin 4 receptor (MC4r) plays an important role in the energy metabolism. We overexpressed the MC4r in CHO cells and performed characterisation studies on the cell membranes to determine functional stability and ligand binding properties of the receptor. The affinity for the ligands [Nle4, Image-Phe7]-αMSH and MTII was lost below pH 6 but could be restored by returning

Placental histology and fetal blood flow in intrauterine growth retardation

OBJECTIVE. To define the histological lesions in the placenta associated with abnormal blood flow findings and to evaluate their possible clinical significance. DESIGN. A prospective blind study. SETTING. A clinical study at a teaching hospital, Malmo General Hospital, University of Lund, Sweden, morphological studies of placentas being performed at the Institute of Pathology, University of Lausan

Correlation between plasma concentrations of calcitonin gene related peptide and pulmonary pressure in patients with systemic sclerosis.

OBJECTIVE: To examine plasma levels of calcitonin gene related peptide (p-CGRP) in patients with systemic sclerosis (SSc) and pulmonary hypertension (PH). MATERIAL AND METHODS: Twenty nine patients with SSc, 10 with diffuse form, 18 with limited form and one with overlapping systemic lupus erythematosus were examined. Twelve patients displayed normal systolic pulmonary artery pressure (PAPsyst) <

Rapid and effective CD3 T-cell depletion with a magnetic cell sorting program to produce peripheral blood progenitor cell products for haploidentical transplantation in children and adults.

BACKGROUND: Effective T-cell depletion is a prerequisite for haploidentical peripheral blood progenitor cell (PBPC) transplantation. This study was performed to investigate the performance of magnetic cell sorting–based direct large-scale T-cell depletion, which is an attractive alternative to standard PBPC enrichment procedures. STUDY DESIGN AND METHODS: PBPCs were harvested from 11 human leukoc

Estimating the parameters of the operational model of pharmacological agonism

The aim of this work is practical. We show that the parameters of the widely used operational model of pharmacological agonism are difficult to estimate from single dose-response curves. The parameters can be estimated using pairs of dose-response curves (usually treatment and control) sharing some parameters. Confidence bands for the estimators are developed. In the case of multiple dose-response

Diversity of dietary patterns observed in the European Prospective Investigation into Cancer and Nutrition (EPIC) project

Objective.. To describe the diversity in dietary patterns existing across centres/regions participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). Design and setting.. Single 24-hour dietary recall measurements were obtained by means of standardised face-to-face interviews using the EPIC-SOFT software. These have been used to present a graphic multi-dimensional com

MR-undersökning av hjärnan vid 3 tesla. Högre magnetfältsstyrka ger bättre morfologisk och funktionell bild

Magnetresonansundersökning med magnetfältsstyrka 3 tesla (3T-MR) ger förbättrade morfologiska och funktionella undersökningar av hjärnan jämfört med de mer vanligt förekommande MR-utrustningarna med fältstyrkan 1,5T eller lägre. Fördelarna med 3T dominerar enligt vår mening markant över vissa nackdelar som den högre fältstyrkan också medför. Kombination med ett kraftfullt gradientsystem ger optima3T MRI offers improved morphological and functional studies of the brain compared with the more commonly used field strength 1.5T. Clinical 3T MRI of the brain is beneficial for high resolution morphological imaging, MR angiography, diffusion-MRI including diffusion tensor imaging, perfusion-MRI, functional MRI (fMRI), and MR spectroscopy. The performance is enhanced by the combination with powerf

Significant impact of 5 alpha-reductase type 2 polymorphisms on sperm concentration and motility

Androgens, including 5 alpha-dihydrotestosterone (DHT), are known to play a role for spermatogenesis and accessory sex gland function. The enzyme 5 alpha-reductase (SRD5A) catalyses the conversion of testosterone to DHT. Our objective was to investigate whether polymorphisms in the SRD5A2 gene influence semen parameters in the general population. DNA from 182 Swedish military conscripts was examin

Flare phenomenon in osteosarcoma after complete remission

A patient undergoing cytostatic therapy for osteosarcoma of the right humerus had bone scans at 2-mo intervals. A skeletal focus of increased radiotracer accumulation occurred and subsequently was confirmed by CT and MRI. A necrotic metastasis was found during biopsy. There were no remaining viable tumor cells. This finding confirms the presence of the flare phenomenon in skeletal metastases in pr