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Adopting a new technology : potatoes and population growth in the periphery

Sweden's population doubled in size between 1750 and 1850 despite a century of stagnating per capita incomes and real wages, which has led many historians to attribute the population explosion to the introduction of the potato. This article provides the first systematic evidence on the potato's contribution to Swedish living standards and population growth. Potatoes at least doubled output per acr

Relative pose estimation in binocular vision for a planar scene using inter-image homographies

In this paper we consider a mobile platform with two cameras directed towards the floor mounted the same distance from the ground, assuming planar motion and constant internal parameters. Earlier work related to this specific problem geometry has been carried out for monocular systems, and the main contribution of this paper is the generalization to a binocular system and the recovery of the relat

SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease

Aims: Metabolic dysfunction is involved in modulating the disease process in Huntington disease (HD) but the underlying mechanisms are not known. The aim of this study was to investigate if the metabolic regulators sirtuins are affected in HD. Methods: Quantitative real-time polymerase chain reactions were used to assess levels of SIRT1-3 and downstream targets in post mortem brain tissue from HD

Medical therapy versus transurethral resection of the prostate (TURP) for the treatment of symptomatic benign prostatic enlargement (BPE) : a cost minimisation analysis

Purpose: A cost minimisation analysis compares the costs of different interventions’ to ascertain the least expensive over time. We compared different prostate targeted drug treatments with TURP to identify the optimal cost saving duration of a medical therapy for symptomatic benign prostatic enlargement (BPE). Methods: The Evolution registry is a prospective, multicentre registry, conducted by th

Disease modification in OA — will we ever get there?

No drugs are currently approved that change the natural course of osteoarthritis (OA) and translate to long-term, clinically relevant benefits. Two-stage clinical trial designs for OA have now received FDA approval, but remaining challenges lie in defining suitable study populations, surrogate outcomes and pivotal long-term, clinically relevant trial endpoints.

Substance P-induced relaxation and hyperpolarization in human cerebral arteries

1. Vascular effects of substance P were studied in human isolated pial arteries removed from 14 patients undergoing cerebral cortical resection. 2. Substance P induced a concentration-dependent relaxation in the presence of indomethacin. No relaxation was seen in arteries where the endothelium had been removed. 3. N omega-nitro-L-arginine (L-NOARG, 0.3 mM) abolished the relaxation in arteries from

Clinical and Biochemical Aspects of the Emergency Management of Traumatic Brain Injury

Populärvetenskaplig sammanfattning(Summary in Swedish)Hjärnskada som orsakas av olyckor är en vanlig orsak till både handikapp och död bland vuxna. För 30 år sedan var majoriteten av de som drabbades yngre eller väldigt gamla. Ålderssammansättningen av de som drabbas har skiftat under de senaste 20 åren och nu är det ungefär lika vanligt i alla åldrar. Dessutom är den vanligaste olycksorsaken inte

Uncomplicated urinary tract infections in Swedish primary care; Etiology, resistance and treatment

Background: Uncomplicated urinary tract infection (uUTI) is common and a majority of patients are prescribed antibiotics. There is little knowledge about antibiotic resistance in urine samples from patients with uUTI in primary health care (PHC). The aim was to describe antibiotic treatment, bacterial findings, the prevalence of resistant E.coli and factors associated with antibiotic resistance. T

Are Food Advertisements Promoting More Unhealthy Foods and Beverages over Time? Evidence from Three Swedish Food Magazines, 1995–2014

Unhealthy food in advertising has been suggested as a mediator for the increase in diet-related illness. This study quantitatively investigates changes in food advertising between 1995 and 2014 in terms of food categories promoted, macronutrient content, and percentage of foods classified as heathy or unhealthy from a sample of 7,199 ads from three Swedish food magazines. With the exception of inc

Home cooking trends and dietary illness : Nutritional compliance of recipes in a Swedish food magazine 1970–2010

Aims: To investigate the trends in nutritional compliance of recipes from a Swedish food magazine to offer a perspective on the effects of home cooking on public health. Methods: The nutritional content of 654 recipes from magazine issues published in 1970, 1980, 2000, and 2010 were collected. The recipes were analyzed for macronutrient energy contribution, sodium content, and composition. Results

Coordination of legislative speech in times of crisis : Youth unemployment and debates on redistributive policies in the Swedish Riksdag, 1994–2014

Parliamentary debates and the discussion on different law proposals are a key part of the process of policy making. We argue in this article that a high economic problem pressure in the region an MP represents will affect the MP’s legislative speechmaking. We also hypothesise that parties tend to coordinate their speakers in parliament to display a cohesive profile in the domain of labour, employm

Carbon cycle data assimilation with a generic phenology model

Photosynthesis by terrestrial plants is the main driver of the global carbon cycle, and the presence of actively photosynthesizing vegetation can now be observed from space. However, challenges remain when translating remotely sensed data into carbon fluxes. One reason is that the Fraction of Absorbed Photosynthetically Active Radiation (FAPAR), which documents the presence of photosynthetically a

Social monitoring via close calls in meerkats

Social monitoring of the actions of group members is thought to be a key development associated with group living. Humans constantly monitor the behaviour of others and respond to them in a flexible way depending on past interactions and the current social context. While other primates have also been reported to change their behaviour towards other group members flexibly based on the current state

A high precision logarithmic-curvature compensated all CMOS voltage reference

This paper presents a resistor-less high-precision, sub-1 V all-CMOS voltage reference. A curvature-compensation method is used to cancel the logarithmic temperature dependence regardless of mobility temperature exponent (γ). The circuit is simulated in 65 nm CMOS technology and yields an output voltage of 594 mV, temperature coefficient of 7ppm∘C in the range of −40 to 125 °C, a power supply reje