The protein biomarker expressions in three types of sampled immune INFILTration spatial niches in lung cancer tissue were measured using the new technology Digital Spatial Profiler (DSP). The three types of immune INFILTration that were observed in lung tumors were STROMA identified as immune cells separate from tumor cells, Tertiary lymphoid structures (TLS) identified as dense structures of orga

Genome-encoded antibiotic resistance (ARE) ATP-binding cassette (ABC) proteins of the F subfamily (ARE-ABCFs) mediate intrinsic resistance in diverse Gram-positive bacteria. The diversity of chromosomally-encoded ARE-ABCFs is far from being fully experimentally explored. Here we characterise phylogenetically diverse genome-encoded ABCFs from Actinomycetia (Ard1 from Streptomyces capreolus, produce

The academic response to Bourdieu's sociology of law has mainly followed his Weberian focus on the role of legal professionals in state transformations. However, rereading Bourdieu's “The Force of Law” through the lens of its references and relating it to the sociology of law “of the moment” (i.e. that of the 1980s), it becomes clear that Bourdieu's sociology of law is more sophisticated than has

Balancing personal desire and social expectations, fathers who seek greater gender equality in the family today often face stereotypes at work and in society. Reflections from a collection of interviews

In this paper, we compare two approaches to numerically approximate the solution of second-order Gurtin–Pipkin type of integro-differential equations. Both methods are based on a high-order Discontinous Galerkin approximation in space and the numerical inverse Laplace transform. In the first approach, we use functional calculus and the inverse Laplace transform to represent the solution. The spect

Railway traffic usually adheres to a timetable, but in Sweden, around two-thirds of the freight trains depart before they are scheduled, often by hours. Even though they occur in real operations, early departures have rarely been included in simulation studies and the effects on punctuality are not fully investigated. With a macroscopic simulation tool such as PROTON, large networks can be simulat

Spirocyclic acetal structures have recently received growing attention in polymer science due to their dual potential to raise the glass transition temperature (Tg) and enable chemical recycling of biobased polymers. In the present work, a vanillin-based diol with a spirocyclic acetal structure was incorporated in a series of rigid amorphous polyesters based on neopentyl glycol and dimethyl t

Under covid-19-pandemin uppmärksammades tillämpningen av handlings-offentligheten. Covid-19-pandemin utgjorde en kris som innebar olika former av påfrestningar för bl.a. svenska myndigheter. Uppsatsens syfte är att utreda och analysera om det finns några inskränkningar i handlingsoffentligheten under normala förhållanden och under särskilda situationer som kris, krigsfara eller krig. Utöver det During the COVID-19 pandemic attention was paid to the right to access official documents. The COVID-19 pandemic constituted a crisis that meant various forms of stress for, among others, Swedish authorities. The purpose of the essay is to examine and analyze whether there are any restrictions on the right to access official documents under normal conditions and during special situations such as

The main purpose of this thesis is to present a Cultural-Historical Activity Theory (CHAT) based analysis of the activities conducted by and with visually impaired users supported by audio-haptic technology.This thesis covers several studies conducted in two projects. The studies evaluate the use of audio-haptic technologies to support and/or mediate the activities of people with visual impairment

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Inflation began to increase rapidly towards the end of 2021 and remained elevated throughout 2022. Higher energy prices contributed significantly to the increase in inflation. However, core-inflation, excluding the direct contribution of energy prices, was also significantly above the European Central Bank’s inflation target. Partially due to the highly expansionary monetary policy during the pandInflation began to increase rapidly all around the world towards the end of 2021, and it remained elevated throughout 2022. Higher energy prices contributed significantly to the increase in inflation. However, core inflation, excluding the direct contribution of energy prices, was also significantly above the European Central Bank’s inflation target, which was partially due to the highly expansion