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Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer
Cysteinyl leukotriene receptor 1 (CysLT1R) has been shown to be up-regulated in the adenocarcinomas of colorectal cancer patients, which is associated with a poor prognosis. In a spontaneous model of colon cancer, CysLT1R disruption was associated with a reduced tumor burden in double-mutant female mice (ApcMin/+/Cysltr1-/-) compared to ApcMin/+ littermates. In the current study, we utilized a gen
Pauses during text writing as a window to linguistic and cognitive development
Integrating engineering design and design analysis activities at an operational level
Computer-based design analysis is nowadays of utmost importance for most engineering design projects. However, this brings some challenges, among them that of the collaboration between engineering designers and design analysts. Since they work with, and are responsible for, different areas, they do not necessarily have full insight into each other’s way of working. The issue of integration between
Documents of Utopia: The Politics of Experimental Documentary
Archival
Interviews for the Samlung Hoffman
”Cinematic Gestures between Henri Michaux and Joachim Koester”
Joachim Koester
Introduction: Towards an Ethics of Gesture
Modelling of the integration tasks of product and packaging development
PurposeThere is a growing demand for a concurrent development of product and packaging in order to better take into account the supply chain needs. Different tasks are required to integrate packaging and product development: 1) At the strategic level, it is necessary to define or refine an integrated development policy; 2) For each new development project, an adaptation of this policy must be unde