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Group A Streptococcus (GAS) is a common and versatile human pathogen causing a variety of diseases. One of the many virulence factors of GAS is the secreted pore-forming cytotoxin streptolysin O (SLO), which has been ascribed multiple properties, including inflammasome activation leading to release of the potent inflammatory cytokine IL-1β from infected macrophages. IL-1β is synthesized as an inac
PurposeThe fast advancement of medical technology and processes poses challenges to hospital construction and management. The purpose of this paper is to provide a structured approach to advancing adaptability in hospital retrofits, proposing the preferable timing and scope of different adaptability strategies.Design/methodology/approachA qualitative research approach was chosen, with 28 semi-stru
Internal mixing on the giant branch is an important process which affects the evolution of stars and the chemical evolution of the galaxy. While several mechanisms have been proposed to explain this mixing, better empirical constraints are necessary. Here, we use [C/N] abundances in 26,097 evolved stars from the SDSS-IV/APOGEE-2 Data Release 14 to trace mixing and extra mixing in old field giants
Three small-scale extinctions occurred in the Early Triassic with one of them recognized close to the Smithian-Spathian boundary. In the last two decades, the end-Permian mass extinction as well as the subsequent recovery have been intensively studied throughout the Tethys region, but correlations within the Lower Triassic are difficult due to conodonts endemism. Here we use paleontological and ge
We present the extension of ptychography for three-dimensional object reconstruction in a tomography setting. We describe the alternating direction method of multipliers (ADMM) as a generic reconstruction framework to efficiently solve the nonlinear optimization problem. In this framework, the ADMM breaks the joint reconstruction problem into two well-defined subproblems: ptychographic phase retri
Objective: Modality and frequency of image-based renal cell carcinoma (R.C.C.) follow-up strategies are based on risk of recurrence. Using the R.E.C.U.R.-database, frequency of imaging was studied in regard to prognostic risk groups. Furthermore, it was investigated whether imaging modality utilized in contemporary follow-up were associated with outcome after detection of recurrence. Moreover, out
Crops with improved uptake of fertilizer phosphorus (P) would reduce P losses and confer environmental benefits. We examined how P-sufficient 6-week-old soil-grown Trifolium subterraneum plants, and 2-week-old seedlings in solution culture, accumulated P in roots after inorganic P (Pi) addition. In contrast to our expectation that vacuoles would accumulate excess P, after 7 days, X-ray microanaly
We study the isotonic regression estimator over a general countable pre-ordered set. We obtain the limiting distribution of the estimator and study its properties. It is proved that, under some general assumptions, the limiting distribution of the isotonized estimator is given by the concatenation of the separate isotonic regressions of the certain subvectors of an unrestrecred estimator’s asympto
The European species of Euplectrus Westwood are comprehensively treated for the first time, using a combination of morphological and DNA data (CO1, the barcode). Ten species are included, seven already described: E. bicolor (Swederus), E. flavipes (Fonscolombe), E. intactus Walker, E. liparidis Ferrière, E. maculiventris Westwood, E. nigriceps Ferrière, E. phthorimaeae Ferrière, and three new spec
We consider a special benchmark mechanical system with two degrees of freedom and underactuation degree one. Furuta Pendulum consists of an arm, rotating in the horizontal plane, and a pendulum, attached to the end of the arm freely and moving in the vertical plane. Our goal is to create and partially shape stable oscillations of the pendulum. The approach is based on the idea of stabilization of
When a manipulator interacts with objects with poorly damped oscillatory modes, undesired oscillations and bouncing may result. In this paper, we present a method for observer-based control of a rigid manipulator interacting with an environment with linear dynamics.The controller injects a desired damping into the environment dynamics, using both visual-and force sensing for stable control of the
The X-ray crystallography station I911-2 at MAXLab II (Lund, Sweden) has been adapted to enable difference small- and wide-angle X-ray scattering (SAXS/WAXS) data to be recorded. Modifications to the beamline included a customized flow cell, a motorized flow cell holder, a helium cone, a beam stop, a sample stage and a sample delivery system. This setup incorporated external devices such as infrar
