Cytogenetic investigation of short-term cultures from two leiomyosarcomas revealed complex karyotypic changes in both cases. The first tumor, a subcutaneous leiomyosarcoma of the knee, had the karyotype 70-80,XY, +X, +Y, +1, +1, +2, +2, +3, +3, +4, +4, +7, +7, +8, +8, +9, +10, +15, +15, +16, +16, +18, +19, +20, +21, +21, +22, +22,t(?;5)(5;21)(?;q35p11;q11), t(?;5)(5;21)(?;q35p11;q11), +del(11)(q22

The pH and salt dependent self-association of hen egg-white lysozyme (HEWL) has been studied extensively, mainly by scattering techniques, but it has proven difficult to distinguish oligomerization from long-range interactions. Because HEWL is the principal model system in studies of protein crystallization, it is important to establish its oligomerization behavior unambiguously. Here, we address

A new approach to calculating the parameters of resonant states is proposed, which also makes it possible to determine the probabilities of the resonant scattering and capture probabilities at the resonant state. This approach is based on the application of the method of configuration interaction, which was proposed for the first time by Fano for an analysis of field ionization of the helium atom.

Background: It has been suggested that neuromuscular function is of importance in the overall outcome after anterior cruciate ligament (ACL) injury. Hypothesis: Good neuromuscular function can be achieved and maintained over time in subjects with ACL injury treated with rehabilitation and activity modification but without reconstructive surgery. Study Design: Case series; Level of evidence, 4. Met

Aims and Methods: The pulmonary and vascular effects of endothelin-1 receptor activation were studied in isolated perfused and ventilated lung preparations from rat. The responses to endothelin-1 (ET-1) and the endothelin B (ETB) receptor agonist sarafotoxin 6c (S6c) were characterized using the endothelin A (ETA)-receptor antagonist FR 139317, the ETB-receptor antagonist BQ 788 and the combined E

When converting fractional (percentage) depth doses to tissue-phantom ratios, one must use a factor that accounts for the different source-to-point distances. Two minor correction factors are also involved. One is the ratio of total to primary dose at the two different distances from the source, for the same depth and field size. This factor is usually ignored. It was determined experimentally tha

The effects of addition of Schwann cells on peripheral nerve regeneration through a novel graft material-the tendon autograft-and a conventional freeze-thawed muscle graft, were studied in the rat sciatic nerve. Adult Schwann cell cultures were established from predegenerated nerves. The Schwann cells were added to the autologous grafts by coculture (tendon autograft) or injection (freeze-thawed m

Rapporten behandlar möjligheterna att med de bästa tekniklösningarna som finns i dag komma fram till hur en energieffektiv enfamiljsvilla bör utföras. Värmelagring med golvvärmesystem, extra isolerat övergolv, reglerbarhet, ekonomisk kalkyl.

The magnitude of the Coulomb mixing parameter delta (l)(IM) has been experimentally deduced, for the first time, for the B decay of Rb-74. Th, estimated magnitude is derived from the feeding of the non-analog first excited 0(+) state in Kr-74. The inferred upper Limit of 0.07% is small compared to theoretical predictions. The half-life was measured to be 64.90(9) ms. (C) 2001 Published by Elsevier

Background: There is increasing appreciation of gender differences in COPD but scant data whether risk factors for tow lung function differ in men and women. We analysed data from 3 years follow-up in 178 women and 464 men with COPD, participants in the Euroscop Study who were smokers unexposed to inhaled corticosteroids. Methods: Explanatory variables of gender, age, starting age and pack-years s

Background: Blood lipid levels including low-density lipoprotein cholesterol ( LDL-C), high-density lipoprotein cholesterol ( HDL-C), and triglycerides ( TG) are highly heritable. Genome-wide association is a promising approach to map genetic loci related to these heritable phenotypes. Methods: In 1087 Framingham Heart Study Offspring cohort participants ( mean age 47 years, 52% women), we conduct

Termen ”kollektiv kollaps” förekommer relativt ofta på dagstidningarnas sportsidor, men inte i den idrottspsykologiska litteraturen. På grundval av beskrivningen av kollektiv kollaps i media föreslås följande definition: Kollektiv kollaps inträffar när en majoritet av spelarna i ett idrottslag plötsligt presterar under förväntad standard i en match av stor, ofta avgörande, betydelse trots en norma

Popular Abstract in Swedish Hur förändras organisationer? Medan statsvetenskaplig ny-institutionell teori är mer inriktad på att förklara varför institutioner är seglivade och svåra att förändra, så antar ekonomisk organisationsteori att organisationer relativt enkelt anpassar sig till omgivningens krav. Det sociala nätverks-perspektivet fokuserar de strukturer av samarbete och tillit som utvecklaNew institutionalist approaches are inherently weak at accounting for institutional change. In this book, social network analysis is proposed as a key to institutional change. The social network perspective focuses emergent patterns of interpersonal interaction and the resulting ties of interpersonal trust. As a complement and contrast to both March and Olsen’s influential new institutionalist "lo

Popular Abstract in Swedish I min avhandling har jag undersökt hur fosfodiesteras 3B (PDE3B) i fettväven styrs vid svar på två typer av hormoner nämligen, insulin och katekolaminer. Det senare innefattar hormoner så som adrenalin och nor-adrenalin. Varför är då detta intressant att veta? I Sverige och världen har mängden människor med fetma under de senaste åren ökat lavinartat, vilket är en stor Insulin induced activation of the cAMP degrading enzyme phosphodiesterase (PDE) 3B in adipocytes is important for insulin mediated inhibition of lipolysis. The aim of this thesis was to contribute with knowledge on the acute activation of PDE3B in response to insulin and catecholamines in adipocytes. The activation of PDE3B was investigated from three different perspectives namely; phosphorylation