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Arterial Injury due to Infections in Early Life-A Possible Link in Coronary Heart Disease (Functional and Structural Studies in Animals and Children)

Although the clinical manifestations of atherosclerotic CHD occur in adult life, the preclinical phase begins long before, seemingly already in childhood. There is supportive evidence from both epidemiological studies and animal experiments that infections could contribute to the pathogenesis of arterial disease, including atherosclerosis. It has been hypothesised that damage to the vascular endot

Globalization and the Transmission of Social Values: The Case of Tolerance

Tolerance – respecting those who are different – is arguably of particular importance in an era of globalization, where a potential for economic, social and personal development is increasingly a function of interaction with others different from oneself. We investigate whether globalization induces parents to want to instill tolerance in their children, the main idea being that this would equip t

A literature review of the sexual health of women with rheumatoid arthritis

Sexual health problems are common for women with Rheumatoid Arthritis, RA. Sexual health is covered in the International Classification of Functioning, Disability and Health (ICF) by two different fields: sexual function and intimate relationships, which are included in the ICF core sets for RA. Most patients with RA are female, and there are differences concerning sexual health between women and

Protein Dynamics Studied by NMR. Kinetics of the Adipocyte Fatty Acid-Binding Protein and Oligomerisation of the Low Molecular Weight Protein Tyrosine Phosphatase.

Popular Abstract in Swedish 1: Tomas Åkerud, doktorand vid Lunds Universitet, har utvecklat en metod för att mäta hur snabbt läkemedelsmolekyler och fettsyror (de naturliga bindarna) tar sig in i och lämnar bindingsfickan i ett protein som är viktigt för fettsyrametabolismen i människa. Proteinet, adipocyt-fettsyrabindande protein (A-FABP), har som funktion att transportera fettsyror, som inte är Nuclear magnetic resonance spectroscopy (NMR) has been used to determine the kinetics of ligand binding to the adipocyte fatty acid-binding protein (A-FABP), as well as the oligomerisation and inter- and intramolecular dynamics of the low molecular weight-protein tyrosine phosphatase (LMW-PTP) in solution. NMR spectroscopy is sensitive to dynamic processes on timescales ranging from picoseconds t

Sodium Butyrate Enhancement of Protein Expression

We studied in chimeric EGFP-Photinus luciferase HeLa cells the expression of fluorescence and luminescence in different cell culture conditions (medium with or without Serum, static or dynamic conditions, in suspension or on microcarriers) as a model to follow the productivity of a recombinant protein. By studying the effect of Butyrate known as general but unpredictable stimulating agent for prot

Klimat och Konsumtion. Tre fallstudier kring styrmedel och konsumentbeteende.

I varje samhälle har konsumenter en avgörande roll för att klimatanpassade varor och tjänster köps, används och till sist källsorteras. En alldeles övervägande andel svenskar har under flera decennier visat sig vara i hög grad miljömedvetna. Klimatförändringar såsom global uppvärmning och ett växande ozonhål har varit bland de aspekter på klimatförändringar man oroat sig mest för. Kunskap om miljö

Finance-specific Factors as Drivers of Cross-border Investment - An OLI perspective

In this paper we empirically test the role of firm-specific financial characteristics as drivers of international investment and production. We hypothesize that financial strength generates advantages that can be exploited through cross-border investment activity. The hypothesis is tested in a series of binary-response models, using a sample of 1379 European non-financial firms’ international acqu

Cygnet or ugly duckling – what makes the difference? A tale of heat-pump market developments in Sweden

Who can pick a winner? Since 1974, various types of targeted support have at different times been directed at the development of the heat pump market in Sweden – which in the following decades oscillated violently between soaring sales and collapse. Eventually, however, small heat pumps for space heating of residential buildings have in recent years securely established themselves as a mature and