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The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: I

Pure and social disparities in distribution of dentists: a cross-sectional province-based study in iran.

During past decades, the number of dentists has continuously increased in Iran. Beside the quantity, the distribution of dentists affects the oral health status of population. The current study aimed to assess the pure and social disparities in distribution of dentists across the provinces in Iran in 2009. Data on provinces' characteristics, including population and social situation, were obtained

Regional values of diffusional kurtosis estimates in the healthy brain.

PURPOSE: To provide estimates of the diffusional kurtosis in the healthy brain in anatomically defined areas and list these along previously reported values in pathologies. MATERIALS AND METHODS: Thirty-six volunteers (mean age = 33.1 years; range, 19-64 years) underwent diffusional kurtosis imaging. Mean kurtosis (MK), radial kurtosis (RK), mean diffusivity (MD), radial diffusivity (RD), and frac

Acoustoelastic Effects on the Resonance Frequencies of Prestressed Concrete Beams – Short-term Measurements

In this study resonant acoustic spectroscopy was applied during static loading and unloading of three prestressed concrete beams in the context of acoustoelasticity. At each load step multiple modes of vibration were measured using an accelerometer and a small impact source. It was found that the measured resonance frequencies increased with increasing compressive stress in a manner which can be p

Human isolates of Listeria monocytogenes in Sweden during half a century (1958-2010)

Isolates of Listeria monocytogenes (n = 932) isolated in Sweden during 1958-2010 from human patients with invasive listeriosis were characterized by serotyping and pulsed-field gel electrophoresis (PFGE) (AscI). Of the 932 isolates, 183 different PFGE types were identified, of which 83 were each represented by only one isolate. In all, 483 serovar 1/2a isolates were distributed over 114 PFGE types

Coronary liposuction during percutaneous coronary intervention: evidence by near-infrared spectroscopy that aspiration reduces culprit lesion lipid content prior to stent placement.

Intracoronary near-infrared spectroscopy (NIRS) in ST-segment elevation myocardial infarction (STEMI) has demonstrated substantial lipid in STEMI culprit plaques. Thrombus aspiration during primary PCI reduces distal embolization and improves reperfusion. This study was performed to examine if aspiration thrombectomy reduces the lipid content of acute coronary syndrome (ACS) culprit plaques.

Search for massive supersymmetric particles decaying to many jets using the ATLAS detector in pp collisions at root s=8 TeV

Results of a search for decays of massive particles to fully hadronic final states are presented. This search uses 20.3 fb(-1) of data collected by the ATLAS detector in root s = 8 TeV proton-proton collisions at the LHC. Signatures based on high jet multiplicities without requirements on the missing transverse momentum are used to search for R-parity-violating supersymmetric gluino pair productio

Improved temperature precision in rotational coherent anti-Stokes Raman spectroscopy with a modeless dye laser

Single-shot thermometry with dual-broadband rotational coherent anti-Stokes Raman spectroscopy that employs amplified spontaneous emission from a broadband modeless dye laser has been examined. Evaluation of single-shot spectra of air, N-2, and O-2 showed an improved temperature precision at room temperature compared with the precision obtained with a conventional dye laser. A comparison was also

A Novel Approach of Retrofitting a Combined Cycle With Post Combustion CO2 Capture

Most state-of-the-art natural gas-fired combined cycle (NGCC) plants are triple-pressure reheat cycles with efficiencies close to 60%. However, with carbon capture and storage, the efficiency will be penalized by almost 10% units. To limit the energy consumption for a carbon capture NGCC plant, exhaust gas recirculation (EGR) is necessary. Utilizing EGR increases the CO2 content in the gas turbine

Phylogenetic relations of the dinoflagellate Gymnodinium baicalense from Lake Baikal

Freshwater dinoflagellates still remain poorly studied by modern biological methods. This lack of knowledge prevents us from understanding the evolution and colonization patterns of these ecologically important protists. Gymnodinium baicalense is the most abundant, and possibly endemic, planktonic dinoflagellate from the ancient Lake Baikal. This dinoflagellate species blooms in the spring under t

The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes

Background. Maternal alloantibodies against HPA-1a can cross placenta, opsonize foetal platelets, and induce neonatal alloimmune thrombocytopenia (NAIT). In a study of 100, 448 pregnant women in Norway during 1995-2004, 10.6% of HPA-1a negative women had detectable anti-HPA-1a antibodies. Design and Methods. A possible correlation between the maternal ABO blood group phenotype, or underlying genot

Palaeoclimate perturbations before the Sheinwoodian glaciation: A trigger for extinctiond during the 'Ireviken Event'

Telychian to Sheinwoodian conodonts (Pterospathodus eopennatus ssp. n. 1 Zone through the Ozarkodina sagitta rhenana Superzone) were studied in detail for their oxygen isotope composition. The Upper Kockelella ranuliformis and Ozarkodina sagitta rhenana Zones represent the peak interval of the Sheinwoodian positive δ18Oapatite excursion reflecting the coolest conditions with marine sea–water tempe

Anomalous celestial polarization caused by forest fire smoke: why do some insects become visually disoriented under smoky skies?

The effects of forest fire smoke on sky polarization and animal orientation are practically unknown. Using full-sky imaging polarimetry, we therefore measured the celestial polarization pattern under a smoky sky in Fairbanks, Alaska, during the forest fire season in August 2005. It is quantitatively documented here that the celestial polarization, a sky attribute that is necessary for orientation

Binding effects in multivalent Gibbs-Donnan equilibrium

The classical Gibbs-Donnan equilibrium describes excess osmotic pressure associated with confined colloidal charges embedded in an electrolyte solution. In this work, we extend this approach to describe the influence of multivalent ion binding on the equilibrium force acting on a charged rod translocating between two compartments, thereby mimicking ionic effects on force balance during in vitro DN

Calibrated pollen accumulation rates as a basis for quantitative tree biomass reconstructions

Recent investigations show that the pollen accumulation rate (PAR) of the common tree taxa is directly related to the biomass and, by inference, to the population size of the taxa around the study site. Fossil PAR records preserved in lakes provide therefore a potential proxy for quantitative biomass and population reconstructions. We use the high-resolution PAR records obtained from two accuratel

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

Genome-wide association studies of breast cancer have identified multiple single nucleotide polymorphisms (SNPs) that are associated with increased breast cancer risks in the general population. In a previous study, we demonstrated that the minor alleles at three of these SNPs, in FGFR2, TNRC9 and MAP3K1, also confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. Three addi

Implications of the view of programs as formal systems

The prevailing view of software development as the production of program systems is abandoned in favor of software development as theory building. This suggests that software development properly should be regarded as a deductive activity following the same methodology as is used in all deductive sciences. Programming is merely the description process in the activity of building theories about thi