Hereditary syndromes causing colorectal cancer include both polyposis and non-polyposis syndromes. Overlapping phenotypes between the syndromes have been recognized and this make targeted molecular testing for single genes less favorable, instead there is a gaining interest for multi-gene panel-based approaches detecting both SNVs, indels and CNVs in the same assay. We applied a panel including 19

Reducing costs and improvement of product quality are considered important to ensure productivity within a company. Quality deviations during production processes and ergonomics have previously shown to be associated. This study explored the relationship between physical workload and real (found during production processes) and potential (need of extra time and assistance to complete tasks) qualit

The thermal stability and the structural evolution of graphene grown on Fe(110) has been studied upon annealing in ultra-high vacuum conditions (UHV, P ≤ 10−9 mbar) and in the presence of gaseous ethylene at a pressure of ∼10−6 mbar by grazing incidence X-ray diffraction. It was observed that upon annealing at temperatures below 630 °C, graphene on Fe is thermally stable. Exposure to ethylene at t

BACKGROUND: More knowledge about how recovery may promote health among parents with small children is needed.OBJECTIVE: To explore whether insufficient time for leisure was associated with poorer perceived health and higher stress in working parents. A further aim was to explore potential gender differences in the association between insufficient time for leisure and poor perceived health.METHODS:

BACKGROUND: Children are being infected by HIV/AIDS mainly through mother-to-child transmission. In Ethiopia currently more than 135,000 children are living with HIV/AIDS. The aim of this study was to describe the pattern of ARV uptake after birth, co-trimoxazole prophylaxis and follow up compliance, and to examine which factors are associated with the intervention outcome.METHODS: A retrospective

In view of global climate change and the increasing energy demand there is a need for renewable energy resources. This thesis discusses an energy-driven biorefinery concept based on the agricultural residues corn stover and wheat straw. The work is divided into two main parts. The first part is concerned with the effects of steam pretreatment and choice of acid catalyst on ethanol and biogas produ

Background: Lesions in the meniscus are risk factors for developing knee osteoarthritis (OA), not least because of the role of the meniscus in the pathological progression of OA. Delayed gadolinium enhanced MRI of cartilage (dGEMRIC) has extensively been used to identify pre-radiographic cartilage changes in OA. In contrast, its counterpart with regard to examination of the meniscus, gadolinium en

In the present study, we observed that laboratory rats readily consumed lyophilized cells of Cupriavidus necator H16 cultivated using palm oil containing 39 wt% poly(3-hydroxybutyrate) [P(3HB)] as sole diet source. The test animals excreted whitish fecal pellets containing 82–97 wt% P(3HB). The remaining impurities could be easily removed by washing the pellets with water and/or low concentrations

To improve the results of Enterprise Systems (ES) implementation projects, new or revised implementation methodologies are introduced by ES vendors. Yet, the innovation and adoption of implementation methodologies (IM), which are computer-based and incorporate both project management and functional components, can be problematic. The purpose of this paper is to describe and explain the adoption of

In most patients, Parkinson's disease is thought to emerge after a lifetime of exposure to, and interaction between, various genetic and environmental risk factors. One of the key genetic factors linked to this condition is α-synuclein, and the α-synuclein protein is pathologically associated with idiopathic cases. However, α-synuclein pathology is also present in presymptomatic, clinically “norma

There was a substantial trade in furs throughout the medieval period, as indicated by a number of written sources. The archaeological evidence for this trade is, however, scant. The discovery of furriers’ workshops depends to a significant extent on the large-scale sieving of soil samples, since most bones from fur-bearing species are small. As large-scale sieving for small bones is not often unde

The European Spallation Source (ESS), planned to be operational in 2019, is anticipated to be the worlds most intense neutron source. The total beam power will be 5 MW. We focus on the impact of manufacturing errors on the beam quality. In particular we assess the emittance dilution which occurs due to Higher Order Modes (HOMs) excited at a harmonic of the bunch frequency. We also discuss some ali

This paper is focused on implementation challenges related to the integration of sustainable mobility in strategic local/regional land use and transport planning. The work was based on a case study of Stockholm, Sweden, focusing on four current plans and strategies of key importance for sustainable mobility. We identify and discuss implementation challenges related to sustainable mobility using a

In this paper we analyse the interplay between services and manufacturing. This is done through identifying and quantifying a direct link between manufacturing exports and the sales by service providers. For identification of this transmittance mechanism, with the help of highly detailed geographic data, we create a Localised Export Exposure (LEE) variable that captures the variation in demand for

Digitalization is considered key to meeting the challenges that face the healthcare sector. However, the results of digitalization initiatives have often been disappointing and the literature has provided a fragmented understanding of the mixed results. While previous studies have generally focused on the advantages and the barriers of adopting healthcare IS, little attention has been paid to unea

OBJECTIVES: Increased vulnerability to stress has been suggested as a possible mechanism behind medically unexplained conditions such as sensitivity to electricity and common smells. This study examined whether subjective environmental annoyance among the general population is associated with increased physiological reactivity or subjective stress scores.METHODS: Four groups were studied (N=141):

This paper reviews the peer-reviewed scientific literature on interventions aimed to reduce human fear of large carnivores in human-large carnivore conflicts. Based on psychological theories, a wide definition of fear was adopted, including fear as an emotion, as a perception and as an attitude. Four major categories of interventions were identified: information and education, exposure to animal a