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Converting resident glia into functional and subtype-specific neurons in vivo by delivering reprogramming genes directly to the brain provides a step forward toward the possibility of treating brain injuries or diseases. To date, it has been possible to obtain GABAergic and glutamatergic neurons via in vivo conversion, but the precise phenotype of these cells has not yet been analyzed in detail. H

Collagen is the most prominent protein in biological tissues. Tissue fixation is often required for preservation or sectioning of the tissue. This may affect collagen nanostructure and potentially provide incorrect information when analyzed after fixation. We aimed to unravel the effect of 1) ethanol and formalin fixation and 2) 24. h air-dehydration on the organization and structure of collagen f

Increasing cultivation of oilseed rape may have consequences for pollinators and wild plant pollination. By providing pollinating insects with pollen and nectar, oilseed rape benefits short-tongued, generalist insect species. Long-tongued bumble bee species, specialized to other flower types, may instead be negatively affected by increased competition from the generalists (e.g. due to nectar-robbi

The national risk assessment (NRA) has recently become a very important component in a country's disaster risk management (DRM) system. The NRA aims to identify threats and hazards that could affect the entire country, and assess their potential likelihood and impacts from a national perspective. Compared to other DRM activities, NRA work is comparatively new, and is often a response to an externa

The Inter-American Court of Human Rights (I-ACtHR) has developed remarkable jurisprudence for the protection of the right to communal property of indigenous and tribal communities with respect to the ancestral lands that they possess and traditionally used-natural resources, in order to guarantee their cultural and economic survival in the Americas. This article critically analyses the legal regim

The so-called Parents' Movement is a Russian conservative grassroots mobilization against a presumed Western cultural attack on Russian tradition and sovereignty. The primary target is an ongoing legal implementation of the UN Convention of the Rights of the Child, which is conceived of as a Western feint contrived by hostile global agencies and a Russian fifth column of treacherous NGOs and state

Urak Lawoi är en ursprungsbefolkning i Andamansjön som bl.a. bor på kända turistöar som Phuket, Phi Phi, Ko Lanta Yai och Ko Lipe utanför Thailands västkust. Deras språk och kultur skiljer sig från övriga thailändares, inte minst ifråga om kunskap att navigera på havet. Att bo på eller vid havet är centralt för deras identitet; det är där de fiskar, samlar föda på stränder och utför sina ritualer.On 26 December 2004, the Urak Lawoi sea people were hit by a huge tsunami that overwhelmed all of Southeast Asia causing the deaths of more than 350,000 people across the region. If the tsunami was the disaster, the “first wave”, the relief efforts and the assistance that came with it became the “second wave”, due to the social and economic changes that followed. The Urak Lawoi have for centuries,

When you fall into a trance traces the relationships between Dominique, a neuroscientist, Simon, her patient, Tony, a synchronized swimmer, and Hugo, an aid worker. Simon is suffering from the loss of his proprioception, his sense of the relative position of his body parts as well as his understanding of the effort required to move them. His vision seems essential to his physical agency—if he cann

BACKGROUND: Medical decision making has long been in focus, but little is known of the preferences and conditions for elderly people with co-morbidities to participate in medical decision making. The main objective of the present study was to investigate the preferred and the actual degree of control, i.e. the role elderly people with co-morbidities wish to assume and actually had with regard to i

OBJECTIVE: To deepen the knowledge of frail elderly patients' preferences for participation in medical decision making during hospitalization.METHODS: Qualitative study using content analysis of semi-structured interviews.RESULTS: Patient participation to frail elderly means information, not the wish to take part in decisions about their medical treatments. They view the hospital care system as an

Objectives: To investigate the correlation between MMSE ≤ 23 and the presence of a diagnosis of dementia in the medical record in a population with multimorbidity. Design, setting, and participants: This cross-sectional study was part of the Ambulatory Geriatric Assessment – a Frailty Intervention Trial (AGe-FIT; N = 382). Participants were community dwelling, aged ≥ 75 years, had received inpatie

With worldwide population aging, increasing numbers of people need hospital care. Evidence suggests comprehensive geriatric assessment (CGA) is superior to usual care. To summarize the evidence for the effects of CGA in frail and moderately frail patients compared with usual care in acute care settings. CINAHL, PsycInfo, Cochrane Library, EMBASE, and PubMed were searched in October 2011, January 2

Background In the coming half-century, the population of old people will increase, especially in the oldest age groups. Therefore, the prevalence of multiple chronic conditions, and consequently, the need of health care including care in hospital, is rising. Materials and methods This article includes results from three mainly qualitative articles (interviews with frail old people, physicians, and