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Background: The complex polarity of neurons requires specialized mechanisms to allocate sufficient number of mitochondria to neurites and synapses to control local calcium and ATP levels. Deficits in trafficking are directly linked to neurodegeneration. Our objective is to demonstrate that alterations of mitochondrial spatial location and metabolism are interconnected and can lead to point-of-no-r
Remediation of contaminated soil and sediment is important for improving the eco-environmental quality. Electro-kinetic remediation (EKR) is an environmentally friendly technology to migrate and remove pollutants from the soil and sediment matrix. This paper analyses the mechanism and performance of EKR of heavy metals, organic pollutants, and compound pollutants. Moreover, the effect of optimizin
We present the results of a near-infrared (NIR) monitoring programme carried out between 1999 and 2005 to determine the variability properties of the 'Arecibo sample of OH/IR stars'. The sample consists of 385 IRAS-selected Asymptotic Giant Branch (AGB) candidates, for which their O-rich chemistry has been proven by the detection of 1612 MHz OH maser emission. The monitoring data were complemented
Context. Under certain conditions, stellar radial velocities can be determined from astrometry, without any use of spectroscopy. This enables us to identify phenomena, other than the Doppler effect, that are displacing spectral lines. Aims. The change of stellar proper motions over time (perspective acceleration) is used to determine radial velocities from accurate astrometric data, which are now
We demonstrate a solution method that allows both elongation rate and average fibril length of assembling amyloid fibrils to be estimated. The approach involves acquisition of real-time neutron scattering data during the initial stages of seeded growth, using contrast matched buffer to make the seeds effectively invisible to neutrons. As deuterated monomers add on to the seeds, the labelled growin
The trace element selenium is of essential importance for the synthesis of a set of redox active proteins. We investigated three complementary serum selenium status biomarkers in relation to overall survival and recurrence following diagnosis of primary invasive breast cancer in a large prospective cohort study. The Sweden Cancerome Analysis Network – Breast Initiative (SCAN-B) is a prospective po
This report summarizes a survey performed in eight countries on the status quo of daylight and electric lighting control systems. Feedback from more than 100 international experts (building / facility managers and planers) was evaluated. The aim of the survey was to identify the perception of the different possibilities of the current lighting control solutions and the expectations about the contr
Vi människor är biologiska varelser och därför sammanvävda med övrigt liv på jorden. Det betyder att vi både för vår överlevnad och för vår vällevnad är helt beroende, inte bara av att det finns en rikedom av liv på planeten, utan också av ett otal ekologiska funktioner som genereras av levande organismer, av enskilda arter eller av flera arter i samspel. Det handlar om direkt livsuppehållande fun
Vårt traditionella jordbrukslandskap är centralt för att bevara biologisk mångfald, men det moderna jordbruket har medfört förändringar som bidragit till en utarmning av mångfalden. Detta hotar de ekosystemtjänster som naturbetesmarker och deras mångfald kan bidra med. Sverige har i tusentals år haft betesdjur som en integrerad del av matproduktionen, vilket har format landskap med en variation av
Pollinatörer är en fråga i tiden. I slutet av 1990-talet introducerade Gretchen Daily och Robert Costanza begreppet ekosystemtjänster för att beskriva människans beroende av naturliga processer och produkter som skapas av våra ekosystem. Begreppet har sedan dess fått ett enormt genomslag inom vetenskap och policy och var centralt för IPBES globala utvärdering av biologisk mångfald och ekosystemtjä
The epoch of the Anthropocene, a period during which human activity has been the dominant influence on climate and the environment, has witnessed a decline in oxygen concentrations and an expansion of oxygen-depleted environments in both coastal and open ocean systems since the middle of the 20th century. This paper provides a review of system-specific drivers of low oxygen in a range of case stud
The town of Blera is situated in the southern parts of Etruria and has a history spanning more than 2,500 years. Its location between the two important Etruscan cities of Tarquinii and Caere has meant that Blera, for the entire Etruscan period (c. 750–50 BC), alternatively has found itself in either city’s sphere of interest. When Rome begins her expansion into Etruria, following the fall of the sThe town of Blera is situated in the southern parts of Etruria and has a history spanning more than 2,500 years. Its location between the two important Etruscan cities of Tarquinii and Caere has meant that Blera, for the entire Etruscan period (c. 750–50 BC), alternatively has found itself in either city’s sphere of interest. When Rome begins her expansion into Etruria, following the fall of the s
I boken beskrivs svenska mätningar av gammastrålning från den ryska ubåten som hösten 1981 gick på grund i Karlskrona skärgård. Båten stod så hårt på grundet att trots idoga försök lyckades den inte ta sig loss. Av praktiska skäl låg en svensk kustbevakningsbåt tätt bredvid den sovjetiska ubåten. Under däck i den svenska båten befann sig författaren till denna bok för att med hjälp av avancerad kä
Background: There is conflicting observational data on the survival benefit cardiac implantable electronic devices (CIED) in patients with LVADs. Methods: Patients in whom an LVAD was implanted between January 2008 and April 2017 in the multinational Trans-Atlantic Registry on VAD and Transplant (TRAViATA) registry were separated into four groups based on the presence of CIED prior to LVAD implant
Background and purpose: Fibroblast growth factor 23 (FGF23) is an osteogenic hormone associated with chronic kidney disease and is an emerging risk factor for several cardiovascular diseases. The association of FGF23 with stroke is unclear. The aim of this study was to investigate the association of FGF23 with incident intracerebral hemorrhage (ICH). Methods: This was a nested case–control study o
