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Molecular methods for identification and characterization of novel papillomaviruses.

Papillomaviruses (PV) are a remarkably heterogeneous family of small DNA viruses that infect a wide variety of vertebrate species and are etiologically linked with the development of various neoplastic changes of the skin and mucosal epithelia. Based on nucleotide similarity, PVs are hierarchically classified into genera, species and types. Novel human PV (HPV) types are given a unique number only

Antiproliferative Activity of Melanoidins Isolated from Heated Potato Fiber (Potex) in Glioma Cell Culture Model

Potex constitutes a potato fiber preparation widely used as an ingredient to meat and bakery products which thermal treatment results in creation of new compounds. Melanoidins are high molecular weight brown end products of Maillard reaction, and few data presenting tumor cell growth inhibiting activity of melanoidins have been reported. Thus, in present study we utilized water extract of Potex ro

Acoustic radiation- and streaming-induced microparticle velocities determined by microparticle image velocimetry in an ultrasound symmetry plane

We present microparticle image velocimetry measurements of suspended microparticles of diameters from 0.6 to 10 mu m undergoing acoustophoresis in an ultrasound symmetry plane in a microchannel. The motion of the smallest particles is dominated by the Stokes drag from the induced acoustic streaming flow, while the motion of the largest particles is dominated by the acoustic radiation force. For al

Environmental Hexachlorobenzene exposure and human male reproductive function.

Hexachlorobenzene (HCB) is a persistent environmental fungicide that may disrupt androgen regulation. The aim of this study was to investigate associations between HCB levels and biomarkers of male reproductive function. 589 spouses of pregnant women from Greenland, Poland and Ukraine were enrolled between 2002 and 2004. The men provided semen and blood samples and were interviewed. HCB was measur

Political Mythmaking and the 2014 Winter Olympics in Sochi: Olympism and the Russian Great Power Myth

The theoretical point of departure of this paper is that the perspective of political myth adds to the understanding of political developments in Russia. The upcoming Olympic Winter Games in Sochi in 2014 are discursively constructed as a manifestation of Russia's return to great power status. In official Russian discourse, there is an encounter between the Russian great power myth and the myth of

The modifier effect in within-category induction: Default inheritance in complex noun phrases.

Within-category induction is the projection of a generic property from a class (Apples are sweet) to a subtype of that class (Chinese apples are sweet). The modifier effect refers to the discovery reported by Connolly et al., that the subtype statement tends to be judged less likely to be true than the original unmodified sentence. The effect was replicated and shown to be moderated by the typical

Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system

Genetic studies have implicated the neuronal ubiquitin C-terminal hydrolase (UCH) protein UCH-L1 in Parkinson's disease (PD) pathogenesis. Moreover, the function of UCH-L1 may be lost in the brains of PD and Alzheimer's disease patients. We have previously reported that the UCH-L1 polymorphic variant S18Y, potentially protective against PD in population studies, demonstrates specific antioxidant f

Stratigraphy of the Triassic-Jurassic Boundary Successions of the Southern Margin of the Junggar Basin, Northwestern China

The Triassic-Jurassic (Tr-J) boundary marks a major extinction event, which (similar to 200 Ma) resulted in global extinctions of fauna and flora both in the marine and terrestrial realms. There prevail great challenges in determining the exact location of the terrestrial Tr-J boundary, because of endemism of. : and the scarcity of fossils in terrestrial settings leading to difficulties in linking

The effect of dietary administration of 2-oxoglutaric acid on the cartilage and bone of growing rats

2-Oxoglutaric acid (2-Ox), a precursor to hydroxyproline - the most abundant amino acid in bone collagen, exerts protective effects on bone development during different stages of organism development; however, little is known about the action of 2-Ox on cartilage. The aim of the present study was to elucidate the influence of dietary 2-Ox supplementation on the growth plate, articular cartilage an

Evaluation of the ductile - brittle transition temperature in the NESC-I material using small punch testing

Small punch (SP) fracture testing with subsequent SEM fractographic analysis was applied to an A 508 Class 3 reactor pressure vessel(RPV) steel, used originally in the NESC-I spinning cylinder experiment, in order to determine the SP ductile-brittle transition temperature of both the base material and the sub-clad heat affected zone. In addition to the evaluation of the SP transition temperature,

Numerically Stable Optimization of Polynomial Solvers for Minimal Problems

Numerous geometric problems in computer vision involve the solu- tion of systems of polynomial equations. This is particularly true for so called minimal problems, but also for finding stationary points for overdetermined prob- lems. The state-of-the-art is based on the use of numerical linear algebra on the large but sparse coefficient matrix that represents the original equations multi- plied wi

Surface complexes of monomethyl phosphate stabilized by hydrogen bonding on goethite (alpha-FeOOH) nanoparticles

Typically, a significant fraction of phosphorus in soils is composed of organic phosphates, and this fraction thus plays an important role in the global phosphorus cycle. Here we have studied adsorption of monomethyl phosphate (MMP) to goethite (alpha-FeOOH) as a model system in order to better understand the mechanisms behind adsorption of organic phosphates to soil minerals, and how adsorption a

Empathy among students in engineering programs

Engineers face challenges when they are to manage project groups and be leaders for organisations because such positions demand skills in social competence and empathy. Previous studies have shown that engineers have low degrees of social competence skills. In this study, the level of empathy as measured by the four subscales of the Interpersonal Reactivity Index, perspective taking, fantasy, empa

Peak oxygen uptake in relation to total heart volume discriminates heart failure patients from healthy volunteers and athletes

Background: An early sign of heart failure (HF) is a decreased cardiac reserve or inability to adequately increase cardiac output during exercise. Under normal circumstances maximal cardiac output is closely related to peak oxygen uptake (VO(2)peak) which has previously been shown to be closely related to total heart volume (THV). Thus, the aim of this study was to derive a VO(2)peak/THV ratio and