It is known that host cells can produce type I IFNs (IFN-alpha beta) after exposure to conserved bacterial products, but the functional consequences of such responses on the outcome of bacterial infections are incompletely understood. We show in this study that IFN-alpha beta signaling is crucial for host defenses against different bacteria, including group B streptococci (GBS), pneumococci, and E

The crucial role of atmospheric CO2 in glacial-interglacial transitions is demonstrated by recent ice-core studies that highlight the importance of accurate CO2 records for our understanding of Quaternary climate dynamics. Previous estimates of CO2 levels during the last interglacial stage (the Eemian) relied on measurements on air trapped in the Antarctic Vostok ice core. Due to uncertainties ass

Previously, time/temperature treatments of starch have been performed mainly on starch/water systems. In this study the same time/temperature treatments were applied to starch/water systems and to potato starch in situ. Two potato varieties (Solanum tuberosum cultivars Asterix and Bintje) were used. The effect of time/temperature treatments on gelatinisation behaviour was evaluated using different

The purpose of this investigation was to evaluate the bone turnover by using bone metabolic markers in relation to previous fracture history and independent of bone mass. Patients and controls were recruited from a population-based study of 193 women, all living in the same city and aged 60, 70, and 80 years. The bone mineral content (BMC) was measured bilaterally in the distal forearm by single-p

BACKGROUND: Factors such as age, sex, behaviour problems, fears, earlier traumatic hospital events and reactions to vaccination were assessed together with behaviour observed before premedication in order to evaluate their importance in predicting response to the anaesthetic process. The anaesthetic process was divided into four endpoints; compliance when given premedication, sedation, compliance

The role of fluid-phase regulators of complement is to inhibit excessive complement activation and maintain homeostasis in blood. By binding to and inactivating complement components on cell surfaces, they can also protect autologous cells from complement-mediated cytotoxicity and phagocytosis. In this study, we wanted to find out whether C4b-binding protein (C4bp), a fluid-phase regulator of the

The aqueous self-assembly of a novel lysine-derived surfactant with a gemini-like architecture, designated here as 12-Lys-12, has been experimentally investigated for the amphiphile alone in water and in a mixture with dodecyltrimethylammonium bromide (DTAB). The neat surfactant forms interesting micrometer-sized rigid tubules in the dilute region, resulting in very viscous solutions. For the cata

The aim of this dissertation is to examine the institutional changes which occurred in Chile under the military regime from 1973-1981, and how these changes can be related to subsequent economic development in the country. The empirical material comprises of an investigation of the new economic policy in the agricultural sector, the political process behind this policy and the social and economic

Popular Abstract in Swedish Avhandlingen behandlar användandet av faltnings koder och Turbo koder för felkorrigering i radio system. Design av koder, avkodare samt metoder för återtransmission behandlas, i syfte att förbättra trafikkapaciteten i digitala radionätverk. Mer specifikt diskuteras design av låg-takts Turbo koder för spritt-spektrum fleranvändarsystem, list sekvens avkodning av länkade New wireless services such as mobile Internet, multimedia streaming and high speed packet data access are making their way to the market. Availability of low-cost equipment providing high transmission quality and efficient spectrum utilization is crucial to the success of these services. This thesis is a collection of papers that address an important step in this direction: efficient error control

Popular Abstract in Swedish Formålet var at undersøge samspillet mellem pårørende til svækkede ældre patienter og sygeplejepersonalet i akutte hospitalsafdelinger, samt at udvikle og teste et instrument til at undersøge, udfra pårørendes perspektiv, samspillets dimensioner i denne kontekst og associationen mellem samspil og tilfredshed med patientforløbet. Den underliggende antagelse for studiet vThe aim was to investigate collaboration between relatives of frail elderly patients and nurses in acute hospital wards, and to develop and test an instrument to investigate, from the relatives? perspective, dimensions of collaboration in this context and the association between collaboration and satisfaction with the hospital care trajectory. The underpinning assumption for the study was that rel

Picolinic acid (PA) protects against quinolinic acid- and kainic acid-induced neurotoxicity in the brain. To study the uptake of PA to the brain, we administered [H-3]PA via a unilateral nasal instillation or iv injection to mice. Autoradiography demonstrated a rapid uptake of radioactivity in the olfactory nerve layer and in the ipsilateral olfactory bulb (OB) following nasal instillation of [H-3

An account of the importance of the photographic documentation of the Nazi concentration camps for the reaction to and understanding of Nazism and the Holocaust.

In this paper we analyse an extremum controller based on a pulsetechnique. The idea is to superimpose probing pulses to the controlsignal and use for feedback the size of the pulse response in the output. Theprobing control strategy has been used with success forthe control of the substrate feeding in E. coli cultivations. The analysis is done here for systems ofHammerstein type with a piecewise a

This paper discusses the use of a transconductor, first proposed by Nauta for high frequency applications, in low frequency CMOS g(m) - C bandpass filters. The behavior of the transconductor is examined in detail, showing that the robust implementation of higher-order low-voltage filters is possible for center frequencies in the lower megahertz region. The experimental results are presented of the

Capillary blood samples from 63 infants collected 3-7 days after birth, and thereafter stored on filter papers for 12-18 y, were tested for the presence of CMV DNA by the polymerase chain reaction (PCR) method. Of 16 infants with proven congenital CMV infection (positive virus isolation test in urine sampled within 1 week of age), 13 (81%) had a positive CMV PCR test and 3 (19%) a negative PCR tes

Aims Subcutaneous injection of recombinant human GAD65 (rhGAD65) in patients with latent autoimmune diabetes in adults (LADA) correlates with an increase in C-peptide levels. In this study we analysed the effect of rhGAD65 administration on the GAD65-specific autoimmune response. Methods Longitudinal serum samples obtained from LADA patients (n = 47) who received 4, 20, 100 or 500 mu g alum-formul