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The Role of Transmural Repolarization Gradient in the Inversion of Cardiac Electric Field : Model Study of ECG in Hypothermia

BACKGROUND: The changes in ventricular repolarization gradients lead to significant alterations of the electrocardiographic body surface T waves up to the T wave inversion. However, the contribution of a specific gradient remains to be elucidated. The objective of the present investigation was to study the role of the transmural repolarization gradient in the inversion of the body surface T wave w

Satisfaction or compensation? The interaction between walking preferences and neighbourhood design

This paper describes a study on preferences, neighbourhood design and walking in a northern European setting. The aim was to examine how preferences for residential choice and modal choice play out regarding walking frequency in three neighbourhoods in the Swedish city of Malmö. The study design, unlike most earlier studies on the walkability of neighbourhoods, treated preferences as explicit vari

How do males recover from eating disorders? An interview study

Objectives: The aim of the current study is toinvestigate what males experience as helpful in theirrecovery process from eating disorders (ED).Methods: Qualitative in-depth interviews within aphenomenological approach, and using contentanalysis to excavate overarching text themes.Setting: Norway and Sweden.Participants: Included were 15 males with an agerange from 19 to 52 years. Duration of illneOBJECTIVES: The aim of the current study is to investigate what males experience as helpful in their recovery process from eating disorders (ED).METHODS: Qualitative in-depth interviews within a phenomenological approach, and using content analysis to excavate overarching text themes.SETTING: Norway and Sweden.PARTICIPANTS: Included were 15 males with an age range from 19 to 52 years. Duration of

The Vakkejokk Breccia : An Early Cambrian proximal impact ejecta layer in the North-Swedish Caledonides

The ≤27 m thick Vakkejokk Breccia is intercalated in autochthon Lower Cambrian along the Caledonian front north of Lake Torneträsk, Lapland, Sweden. The spectacular breccia is here interpreted as a proximal ejecta layer associated with an impact crater, probably ~2-3 km in size, located below Caledonian overthrusts immediately north of the main breccia section. The impact would have taken place in

Relation and technique in psychotherapy: Two partly overlapping categories.

The terms relation and technique are frequently used in discussions of what is effective in psychotherapy, but often on the assumption that they refer to conceptually separate phenomena. The present article questions this dichotomy between relationship and technique. This is done on the basis of a theoretical analysis of the concepts of technique and relationship, and the variety of phenomena they

Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo

Mechanistic details of mammalian metabolism in vivo and dynamic metabolic changes in intact organisms are difficult to monitor because of the lack of spatial, chemical, or temporal resolution when applying traditional analytical tools. These limitations can be addressed by sensitivity enhancement technology for fast in vivo NMR assays of enzymatic fluxes in tissues of interest. We apply this metho

Migrant care workers and rehospitalization among older patients discharged from acute care hospitals

Aim: The relationship between support at home and rehospitalization has not been extensively studied until now. In particular, little is known about the impact of being assisted by migrant care workers (MCW) and rehospitalization. We aimed at investigating such a relationship in a population of older patients discharged from hospitals. Methods: Our series consisted of 506 patients aged 65 years or

Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer

Survivin is an oncogene that functions in cancer cell cytoprotection and mitosis. Here we report that differential expression in cancer cells of a C-terminal splice variant of survivin, termed survivin-ΔEx3, is tightly associated with aggressive disease and markers of unfavorable prognosis. In contrast to other survivin variants, survivin-ΔEx3 localized exclusively to nuclei in tumor cells and was

The Report-AGE project : a permanent epidemiological observatory to identify clinical and biological markers of health outcomes in elderly hospitalized patients in Italy

Background: Italy is expected to experience the largest growth in persons ≥65 years (>20 % by 2020). This demographic shift allows for geriatric research on predictive clinical and biological markers of outcomes related to frailty, re-hospitalization and mortality. Aims: To describe rationale and methods of the Report-AGE study project of acute care patients in Italian National Research Center on

Effectiveness of non-surgical periodontal therapy in a large Chinese population with chronic periodontitis

Aim: The aim of this study was to evaluate the effectiveness of non-surgical periodontal treatment (NSPT) and its influential factors in a large Chinese population with chronic periodontitis. Methods: Periodontal examination data of 10,789 patients with at least one periodontal re-evaluation record were extracted from a hospital-based electronic periodontal charting record system. Probing depth (P

Thyroid and islet autoantibodies predict autoimmune thyroid disease already at Type 1 diabetes diagnosis

CONTEXT: Screening of autoimmune thyroid disease in children and young adults with Type 1 diabetes is important but vary greatly between clinics.OBJECTIVE: The aim was to determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA- DQ at diagnosis of Type 1 diabetes for autoimmune thyroid disease during subsequent follow-up.SETTING: 43 Paediatric Endoc

Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii

POPULAR SCIENTIFIC SUMMARYI was on my way home, sitting on the bus. My tired eyes swept through the pages of the local newspaper and that was the moment I met Lisa. She had previously been diagnosed with cancer. She had recovered and was back to her daily life. Unfortunately the cancer has come back and it has spread to several organs. Lisa as a mother of two kids, as a wife, as a daughter, as a sTelomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins.When a cell replicates its chromosomes, a certain piece of DNA is lost from chromosomal ends due to the ´´ end replication problem´´. This progressive shortening of telo