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Search for a heavy charged boson in events with a charged lepton and missing transverse momentum from pp collisions at s =13 TeV with the ATLAS detector

A search for a heavy charged-boson resonance decaying into a charged lepton (electron or muon) and a neutrino is reported. A data sample of 139 fb-1 of proton-proton collisions at s=13 TeV collected with the ATLAS detector at the LHC during 2015-2018 is used in the search. The observed transverse mass distribution computed from the lepton and missing transverse momenta is consistent with the distr

Patient-reported outcomes and preferences for colon capsule endoscopy and colonoscopy : A systematic review with meta-analysis

Colon capsule endoscopy as an alternative to colonoscopy for the diagnosis of colonic disease may serve as a less invasive and more tolerable investigation for patients. Our aim was to examine patient-reported outcomes for colon capsule endoscopy compared to conventional optical colonoscopy including preference of investigation modality, tolerability and adverse events. A systematic literature sea

PON-Sol2 : Prediction of effects of variants on protein solubility

Genetic variations have a multitude of effects on proteins. A substantial number of variations affect protein–solvent interactions, either aggregation or solubility. Aggregation is often related to structural alterations, whereas solubilizable proteins in the solid phase can be made again soluble by dilution. Solubility is a central protein property and when reduced can lead to diseases. We develo

Tourism and the Capitalocene : From Green Growth to Ecocide

Tourism makes substantial contributions to the Anthropocene. However, the Anthropocene is highly uneven over space and time reflecting the uneven processes of capital accumulation. As a result, the Anthropocene, and tourism's role within it, is best understood as a system of power, profit and re/production in the web of life, what is referred to as the capitalocene. In other words, it is the relat

Assessing community health governance for evidence-informed decision-making : a cross-sectional study across nine districts of India

Purpose: The authors intend to assess the village health sanitation and nutrition committees (VHSNC) on six parameters, including their formation, composition, meeting frequencies, activities, supervisory mechanisms and funds receipt and expenditures across nine districts of the three states of India. Design/methodology/approach: The cross-sectional study, conducted in the states of Uttar Pradesh

Air Pollution and Urban Green Space : Evidence of Environmental Injustice in Adama, Ethiopia

While air pollution data in Ethiopia is limited, existing studies indicate high levels of both ambient and household air pollution; rapid urbanization also threatens the preservation of urban green spaces. In this study, environmental injustice, or the disproportionate burden of environmental exposures on persons of lower socioeconomic status (SES), was explored among women in Ethiopia using a mot

A Security Framework in Digital Twins for Cloud-based Industrial Control Systems: Intrusion Detection and Mitigation

With the help of modern technologies and advances in communication systems, the functionality of Industrial control systems (ICS) has been enhanced leading toward to have more efficient and smarter ICS. However, this makes these systems more and more connected and part of a networked system. This can provide an entry point for attackers to infiltrate the system and cause damage with potentially ca

Gaming Activity and Possible Changes in Gaming Behavior Among Young People During the COVID-19 Pandemic : Cross-sectional Online Survey Study

Background: Young people's daily lives and social interactions changed remarkably during the COVID-19 pandemic as schools and cinemas closed, leisure activities were cancelled, and gatherings were regulated. Questions have been raised by the media, schools, policy makers, and research communities about the effect on young people's online behaviors. Objective: This cross-sectional study aimed to st

Higher Education and Research Policies : the current global agenda and implications for international cooperation

International collaboration is clearly a key priority in higher education andresearch (HER) policy and practice. The competition for students and excellentresearch and teaching staff is now a global one and this is reflected inthe increasing salience of phenomena such as the Shanghai and Times HigherEducation Rankings for monitoring the performance of HER institutions. Thischapter takes its point

Crystal structure of reduced protein R2 of ribonucleotide reductase : The structural basis for oxygen activation at a dinuclear iron site

Background: Ribonucleotide reductases (RNRs) catalyze the formation of the deoxyribonucleotides that are essential for DNA synthesis. The R2 subunit of Escherichia coli RNR is a homodimer containing one dinuclear iron centre per monomer. A tyrosyl radical is essential for catalysis, and is formed via a reaction in which the reduced, diferrous form of the iron centre activates dioxygen. To help und

Structural comparison of two strains of foot-and-mouth disease virus subtype O1 and a laboratory antigenic variant, G67

Background: Foot-and-mouth disease viruses (FMDVs) are members of the picornavirus family and cause an economically important disease of cloven-hoofed animals. To understand the structural basis of antigenic variation in FMDV, we have determined the structures of two viruses closely related to strain O1BFS whose structure is known. Results The two new structures are, like O1BFS, both serotype O vi

The contribution of latent factors of executive functioning to mind wandering: : An experience sampling study

Accumulating evidence suggests that individuals with greater executive resources spend less time mind wandering.Independent strands of research further suggest that this association depends on concentration and a guiltydysphoricdaydreaming style. However, it remains unclear whether this association is specific to particular featuresof executive functioning or certain operationalizations of mind wa