In this chapter we present a non-destructive method for characterizing buried interfaces with high depth resolution combining X-rays standing wave and photoemission electron spectroscopy. This method incorporates the power of the X-rays photoelectron spectroscopy, which is a surface sensitive technique in the nanometer and sub-nanometer regime, with the depth selectivity of X-ray standing wave. Th

RNA therapeutics is a new class of targeted therapies that has entered the clinic in the last decade. Lipid nanoparticles (LNPs) and conjugation to N-acetylgalactosamine have proven to be efficient strategies to deliver RNA payload to the liver. Successful delivery of sensitive RNA molecules to other target tissues or tumors remains one of the key challenges with the development of new RNA-based t

Background: Photon-counting computed tomography (PCCT) is a new clinical method that may show better diagnostic quality at lower radiation doses than conventional CT. Objective: To investigate the diagnostic quality and radiation dose of paediatric cardiovascular PCCT for diagnosis of congenital heart defects at 70 kV and 90 kV. Materials and methods: This retrospective assessment included clinica

The term “Holocene temperature conundrum” refers to the inconsistencies between proxy-based reconstructions and transient model simulations, and it challenges our understanding of global temperature evolution during the Holocene. Climate reconstructions indicate a cooling trend following the Holocene Thermal Maximum, while model simulations indicate a consistent warming trend due to ice-sheet retr

SiC fibre reinforced metal matrix composites find widespread application but show major machining difficulties due to significant variations in constituents' properties. In this sense, while the SiC fibre plays significant strengthening effects, the properties mismatch between the brittle fibre and ductile matrix materials becomes important in their machining performance. Through machining tests,

Despite a large literature on the importance of childhood neighborhoods for life course transitions, there is a lack of fertility studies combining a life-course perspective with detailed neighborhood measures. Addressing this gap, we use longitudinal data in which the entire population of a Swedish town is geocoded at the address-level, 1939–1967, and linked to national registers from 1968 to 201

In this work, we present a method to fabricate a hyaluronic acid (HA) hydrogel with spatially controlled cell-adhesion properties based on photo-polymerisation cross-linking and functionalization. The approach utilises the same reaction pathway for both steps meaning that it is user-friendly and allows for adaptation at any stage during the fabrication process. Moreover, the process does not requi

This review article describes microfabrication techniques to define chemical, mechanical and structural patterns in hydrogels and how these can be used to prepare in vivo like, i.e. biomimetic, cell culture scaffolds. Hydrogels are attractive materials for 3D cell cultures as they provide ideal culture conditions and they are becoming more prominently used. Single material gels without any modific

From 2014 to 2016, 44,617 unaccompanied refugee minors (URMs) arrived in Sweden and sought asylum. The Church of Sweden has received hundreds of these young people seeking to join the church and be baptised as Christians. Conversion to Christianity among asylum seekers in Europe is a well-documented phenomenon that is often dismissed as merely a strategy to boost asylum chances. This dissertation

OBJECTIVES: Bacterial infections are common and a major cause of morbidity and mortality in multiple myeloma (MM). We have investigated the function of polymorphonuclear leukocyte (PMN), the immune system's first line of defense against bacteria, in peripheral blood (PB) and bone marrow (BM) samples from patients with newly diagnosed MM (NDMM), smoldering MM (SMM), monoclonal gammopathy of undeter

Denna rättsutredning har tillkommit på uppdrag av Utredningen om hantering av EU-medel och ingår som en bilaga i utredningens slutbetänkande SOU 2024:22 (bilaga 4). Det övergripande temat är strukturfondspartnerskapens rättsliga status, men även ett antal andra frågor med relevans för utredningens arbete berörs, såsom jäv.

The thesis revolves around the study of glycoside hydrolases (GH), specifically GH5 β-mannanases and GH36 α-galactosidase (I-III), as well as a GH130 mannoside phosphorylase (I, IV). These enzymes are investigated for their actions on and conversion of hemicellulosic β-mannan, including food-grade galactomannan and softwood galactoglucomannan, along with manno-oligosaccharides (MOS) derived from s

On April 1, Israel launched its latest attack on Iran in the two countries’ ongoing shadow war, with an airstrike that flattened a section of Iran’s embassy complex in Damascus and reportedly killed at least 12 people. Among the dead was Mohammad Reza Zahedi, who headed Iran’s military operations in Syria and Lebanon, where he worked for decades and became a close interlocutor with Hezbollah and i

Föreliggande rapport kan ses som en fortsättning på uppföljningen av nära vård och mobila team som redovisas i KEFU rapporten; Samordnad och personcentrerad vård i hemmet - En fallstudie av Mobilt team Närsjukvård Landskrona” (KEFU rapport 2023:1). Uppföljningen av pilotprojektets första fem månader i Landskrona visade på många positiva effekter. Föreliggande rapports uppföljning efter ett års erf

Nanoparticles (NPs) are currently developed for drug delivery and molecular imaging. However, they often get intercepted before reaching their target, leading to low targeting efficacy and signal-to-noise ratio. They tend to accumulate in organs like lungs, liver, kidneys, and spleen. The remedy is to iteratively engineer NP surface properties and administration strategies, presently a time-consum