Popular Abstract in Swedish Årligen diagnostiseras cirka 60 000 nya fall av cancer i Sverige (Socialstyrelsen, 2015), och var tredje person beräknas få en cancerdiagnos under sin livstid. Trots stora framsteg inom forskning och utveckling är cancer, näst efter hjärt- och kärlsjukdomar, den vanligaste dödsorsaken i vårt samhälle. Bland de tio vanligaste formerna av cancer hör lymfom, vilket är etMantle cell lymphoma (MCL) is an aggressive form of B-cell lymphoma (BCL) with poor clinical outcome. In this thesis, which is based upon five original papers, different approaches have been used to pinpoint and investigate molecular events that promote MCL tumor growth, progression or resistance to treatment. The aim has been to identify novel targets with the potential to eradicate malignant cel

Popular Abstract in Swedish Kvinnor känner till att det är riskabelt att röka när de blir gravida. Trots detta så slutar bara omkring hälften i Sverige och var tredje kvinna i många andra länder att röka när de blir gravida. Syftet i den här avhandlingen har varit att studera varför det är så svårt för gravida kvinnor att sluta röka. Problemområdet har studerats med olika utgångspunkter; gravida kThe aim of this thesis has been to increase understanding on the process of smoking cessation during pregnancy from the perspective of learning. The smoking pattern before and after pregnancy related to health, Sense of Coherence (SOC) and social issues was studied among all pregnant women in south-east Skåne during the period March 1994 to August 1995. They were asked to fill in a questionnaire d

Shear and compaction bands represent two fundamental failure modes in sandstones. The identification of these features in both the natural outcrops and the laboratory scale yields useful insights into the mechanisms of localised deformation. Several conventional and advanced experimental full-field methods have been developed in order to shed light into the processes involved, as well as qualify a

This paper deals with bandwidth allocation in a Bluetooth scatternet. The proposed assignment of transmission rights provides a controlled traffic transfer between Bluetooth piconets and represents a key component in an ad-hoc wireless Bluetooth network in order to provide with efficient data packet passing within and across piconets. This assignment is obtained by executing a distributed algorith

The multihadron production in the reaction e(+)e(-) -> e(+)e(-) + hadrons has been studied for the first time at LEP2 energies with both scattered e(+) and e(-) detected at very low Q(2), measured by the DELPHI VSAT. A reasonable agreement between data and full simulation is demonstrated and the total gamma gamma hadronic cross-section is estimated for the gamma gamma center of mass energy up to 1

Use of the new resist system mr-L 6000.1 XP in combination with PMMA is demonstrated to give sub-100 nm resolution in nanoimprint lithography. Low glass transition temperature in combination with high plasma stability makes this resist suitable for achieving desirable resist profiles after the imprint process. Imprint conditions for mr-L 6000.1 XP/PMMA resist system as well as imprint results are

Ideological study of Ingmar Bergman's television series Scenes from a Marriage.

Popular Abstract in Swedish Den cancerskyddande genen p53 är av betydelse för att göra leukemiceller friska. Blodbildning. Blodceller är nödvändiga för vårt välbefinnande och vår överlevnad. Det finns flera olika typer med egna specialiserade funktioner. Så krävs t. ex. röda blodkroppar för syresättning och vita blodkroppar för att bekämpa infektioner. Blodcellerna har begränsad överlevnad; när Leukemic cells suffer from an impaired ability to differentiate due to inherited or acquired genetic lesions. These genetic changes can sometimes be bypassed with various compounds both in vitro, and, more rarely, in vivo, thus inducing terminal differentiation of the leukemic cells. Differentiation of both leukemic and normal hematopoietic cells is believed to be intimately coupled to cell cycle

In this paper, the critical factors behind commercialization of new product development (NPD) are investigated in order to add to our understanding of what drives and hampers the commercialization of new products and services. With the illustration of nine cases of commercialization from three multinational organizations, an initial framework of three categories of factors related to the success o