The central nervous system (CNS) relies on an uninterrupted supply of oxygenated blood, glucose and nutrients for efficient function. Transportation of these fuels is vitally dependent on adequate blood flow through patent brain vessels with the capacity to respond readily to metabolic demands. If the oxygen or glucose content or the flow of blood falls below the level needed to maintain nervous t

Skin barrier damage and subsequent development of harmful microbiota contribute to conditions such as wound infections, atopic dermatitis and chronic wounds, which impact millions of people globally and pose a significant economic burden on healthcare systems. Established microbial sampling methods, such as swabs and tissue biopsies, provide limited information on the spatial distribution of bacte

Multimorbidity, i.e., the presence of two or more long-term health conditions, is challenging for healthcare systems worldwide. A related term is comorbidity. This denotes any condition that has existed or may occur during the clinical course of a patient who has the index disease under study. Moreover, frailty is also inter-related with multimorbidity but represents a distinct clinical concept. F

The phytochemical composition, in vitro antioxidant and antimicrobial activities, cytotoxicity and antigenotoxicity of fruit extracts of Opuntia dillenii were studied. The phytochemical composition was evaluated using HPLC, GC-MS and UV–Vis spectrophotometry. Spectrophotometrical methods were used to estimate the antioxidant potential. Antimicrobial activity was determined using a microdilution me

HPLC-PDA-MS/MS analysis of Syzygium jambos leaf extract allowed the identification of 17 secondary metabolites, including flavonol glycosides, flavonol di-glycosides, and flavones as well as ellagitannins and phenolic acids. The extract showed promising antioxidant activities in different experimental models. In Caenorhabditis elegans, the extract mediated a dose dependent survival rate and decrea

UVA radiations contribute up to 95% of the total UV exposure and are known to induce cell damage, leading to apoptosis. Since the benefic effects of ascorbic acid on human health are well known, a new tomato genotype (named DHO4), highly rich in ascorbic acid, has been recently obtained. Here, we compared the effects of ascorbic acid and hydrophilic DHO4 extracts in protecting human keratinocytes

Objective: The antioxidant activity and protective effect of a methanolic extract obtained from the marine Gram-negative bacterium Novosphingobium sp. PP1Y, isolated from the surface water of a polluted area in the harbour of Pozzuoli (Naples, Italy), was evaluated. Results: The extract was tested in vitro on epithelial colorectal adenocarcinoma cells and in vivo on Caenorhabditis elegans. It show

Ethnopharmacological relevance: The red Brazilian cherry, Eugenia uniflora, is widely used in traditional medicine. The aim of this study was to investigate the phytochemical composition of a methanol extract from leaves of E. uniflora and characterization of the isolated compounds. In addition, we aimed to determine the antioxidant activities in vitro and in a cell-based (HaCaT cell)model. We als

We investigate nonequilibrium transport of charge and heat through an interacting quantum dot coupled to a finite electron reservoir. Both the quantum dot and the finite reservoir are coupled to conventional electric contacts, i.e., infinite electron reservoirs, between which a bias voltage can be applied. We develop a phenomenological description of the system, combining a rate equation for trans

This paper critiques the assumption that capitalist agriculture inherently develops productive forces, highlighting its internal contradictions and questioning its sustainability as a viable agricultural model. Using immanent critique, the paper engages with the capitalist framework on its own terms to demonstrate how its focus on profit maximisation and short-term productivity leads to long-term

We investigate the link between the internal microstructure of poly(N-isopropylacrylamide)-poly(ethylene glycol) methyl ether methacrylate (PNIPAM-PEGMA) microgels, their bulk moduli and the rheological response and structural arrangement in dense suspensions. The low degree of crosslinking combined with the increased hydrophilicity induced by the presence of PEGMA results in a diffuse, star-like

This study explored how the Swedish Fire and Rescue Service identifies problems and implements necessary actions during complex problem-solving in emergencies, aiming to increase our understanding of this process. Primary and secondary data from large-scale fire events were analyzed, including semistructured interviews and incident reports. The concept of “possibility space” is applied to identify

As part of the project FIRE21, a workshop was organised in Trondheim on September 8, 2023, inviting all project partners (Lund University, Research Institutes of Sweden, the Technical University of Denmark and the Norwegian University of Science and Technology) to brainstorm on potential problems for the fire and rescue services (FRS) in the 21st century, and recommendations on how to improve the

Introduction: Having many melanocytic nevi on the skin is a risk factor for melanoma. However, the reproducibility of nevus counts in previous studies is limited due to high inter- and intraobserver variation. Despite the introduction of a protocol for counting and reporting of nevi in 1990 by the International Agency for Research on Cancer (IARC), significant variations in nevus counting methods

This report summarises the results from an interview and literature study carried out to identify key individual qualities for collective problem-solving in a fire and rescue service context. The report contributes to the research project FIRE21 (Fire and Rescue Services in the 21st Century) and is part of a work package looking into such individual qualities through using different methods and ma

The paper details a study that investigated dimensions of mind perception in social agents across various agent types. Factor analysis on 18 mental capacities was conducted across 12 characters, which included 9 social agents - 3 chatbots, 3 voice assistant speakers, and 3 robots. Two factors were identified that roughly aligned with task-oriented and affective-reflective cognitive processes. Base

I denna rapport sammanställer vi resultaten från två workshops som utförts som en del av projektet FIRE21 (Fire and Rescue Services in the 21st Century). I projektet studerar vi (forskare från Sverige, Norge och Danmark) hur räddningstjänster löser problem i så kallade problemlösande nätverk. Vi ser dessa som nödvändiga för att lösa problem i dagens och morgondagens insatser, där vi behöver olika

We study the problem of obtaining lower bounds for polynomial calculus (PC) and polynomial calculus resolution (PCR) on proof degree, and hence by [Impagliazzo et al.'99] also on proof size. [Alekhnovich and Razborov'03] established that if the clause-variable incidence graph of a conjunctive normal form (CNF) formula F is a good enough expander, then proving that F is unsatisfiable requires high

I denna rapport sammanställer vi resultaten från en workshop med Hovedstadens Beredskab i Danmark. Workshopen utfördes som en del av projektet FIRE21 (Fire and Rescue Services in the 21st Century). I projektet studerar vi (forskare från Sverige, Norge och Danmark) hur räddningstjänster löser problem i så kallade problemlösande nätverk. Vi ser dessa som nödvändiga för att lösa problem i dagens och I denna rapport sammanställer vi resultaten från en workshop med Hovedstadens Beredskab i Danmark. Workshopen utfördes som en del av projektet FIRE21 (Fire and Rescue Services in the 21st Century). I projektet studerar vi (forskare från Sverige, Norge och Danmark) hur räddningstjänster löser problem i så kallade problemlösande nätverk. Vi ser dessa som nödvändiga för att lösa problem i dagens och