(1) Autoantibodies to the leucine variant of neuropeptide Y (NPY-LA) have been found in individuals with type 1 diabetes (T1D). We investigated the association between the levels of NPY-LA and single nucleotide polymorphisms (SNP) to better understand the genetic regulatory mechanisms of autoimmunity in T1D and the functional impacts of increased NPY-LA levels. (2) NPY-LA measurements from serum a

It was a great surprise when Hans Lewy in 1957 presented a non-vanishing complex vector field that is not locally solvable. Actually, the vector field is the tangential Cauchy-Riemann operator on the boundary of a strictly pseudoconvex domain. Hörmander proved in 1960 that almost all linear partial differential equations are not locally solvable. This also has connections with the spectral instabi

In this paper, the effects of internal coolant crossflow on double-jet holes were simulated and compared with two rows of cylindrical holes under three blowing ratios (M = 0.5, 1.0, and 1.5), with an established and validated turbulence model. The results show that double-jet holes can provide better film cooling performance for the three different blowing ratios compared with cylindrical holes. A

Purpose Pretreatment prostate-specific antigen (PSA) dynamics (PSA velocity and PSA doubling time) are widely advocated as useful prognostic markers in prostate cancer. We aimed to assess the published evidence for the clinical utility of PSA dynamics in this population. Methods We conducted a systematic review of studies published before March 2007 in which a PSA dynamic (velocity or doubling tim

Summary Semenogelin is the predominant protein in human semen. It is synthetised by the secretory epithelium of the seminal vesicles as a 461 amino acid precursor protein. Following cleavage of a predominantly hydrophobic signal peptide, the secreted protein contains 439 amino acid residues. The amino acid sequence of semenogelin has a repetitive structure, but it displays no significant homology

The predominant protein in human seminal vesicle secretion constitutes the structural protein of coagulated semen. This high molecular weight protein (HMW-SV-protein) is stable in seminal vesicle secretion during in vitro storage at 37 d̀C for at least 20 h, but is rapidly cleaved on mixing with prostatic proteases. Seminal coagulate, washed free of souble components, is dissoluble by 2 to 3 mol/1

The predominant basic protein in liquefied human seminal plasma is the major degradation product of the gel-forming protein secreted by the seminal vesicles. The amino acid sequence of this basic protein is presented. The basic protein contains 52 amino acid residues. It is devoid of cysteine, methionine, tryptophan, and leucine, but contains seven histidine residues located in the NH2-terminal ha

Motivated by the novel coronavirus disease (COVID-19) pandemic, this paper aims to apply Gunter Stein's cautionary message of respecting the unstable to the problem of controlling the spread of an infectious disease. With this goal, we study the effect that delays and capacity constraints have in the test, trace, and isolate (TeTrIs) process, and how they impact its ability to prevent exponential

Talking about inclusion in the workplace is an emerging concept, and the pressure of committing to work with it rests on the companies. The research conducted around inclusion is growing, and there are different suggestions as to how to define and work with the concept. Moreover, companies are lacking evidence to support how to successfully measure it among employees. By exploring inclusion in a s

Denna studie ser på Digitala tokens, och vilka problem som kan stötas på vid en implementering. Genom att observera CBDC har studien kunnat se på digitala tokens i ett annat ljus än tidigare forskning, då majoritet av forskningen på digitala tokens har varit ifrån nischade användningsområden med begränsade fynd. Fyra respondenter som har varit delaktiga i CBDC projektet E-krona piloten, som besitt

Denna studie problematiserar rättstillämpningen i fall där brottsrubriceringen “Våldtäkt mot barn” ogillas som domslut och “Sexuellt övergrepp mot barn” tillämpas istället. Studien analyserar domstolens argument och rättstillämpningen för dessa brott mot barn. Problemformuleringen som tillämpas i denna studie har utgångspunkt i frågeställningen, “Hur argumenterar domstolen kring rubriceringen sexu

Buildings are a are a major consumer of energy in urban areas. The use of solar energy in buildings can help reduce CO2 emitting energy consumption in these urban areas. One way to use solar energy is through passive solar energy systems. Passive solar energy systems allow a building to use daylight as an energy source. The use of daylight as passive solar energy in Sweden could reduce the energy

The influence of gender is increasingly emphasized as an important component to consider in relation to climate change and adaptation. Despite this, it is still relatively unclear how civil society actors address and incorporate gender dimensions into climate change and adaptation practices. Based on qualitative interviews with practitioners working at different civil society organizations in Ugan

Philosophers of science have in recent years become increasingly interested in the notion of interdisciplinarity. One important form interdisciplinarity can take is that of a dynamic exchange of problems and solutions between disciplines— what has recently been called problem-feeding. On this model problems arising within specific disciplines are sometimes solved more effectively by, or in collabo

β microseminoprotein (β inhibin, PSP94), an unglycosylated protein of 94 amino acids with unknown function, is one of the predominating proteins in the secretion of the human prostate gland. In this work the authors have demonstrated that the expression of β microseminoprotein is not restricted to the prostate and that the protein has a previously unrecognized widespread occurrence in the human bo

Analyses of the proteins of azoospermic ejaculates from subjects with defective seminal vesicles demonstrated that three prostatic‐secreted proteins were predominant. Prostatic acid phosphatase (PAP), prostate‐specific antigen (PSA; or γ‐seminoprotein), and β‐microsemi‐noprotein (β‐MSP; or β‐inhibin), were identified as the three predominant proteins secreted by the normal human prostate gland. Im

The impact on the performance of GaN high electron mobility transistors (HEMTs) of in situ ammonia (NH3) pre-treatment prior to the deposition of silicon nitride (SiN) passivation with low-pressure chemical vapor deposition (LPCVD ) is investigated. Three different NH3 pre-treatment durations (0, 3, and 10 min) were compared in terms of interface properties and device performance. A reduction o

Alpha-ketoglutarate (AKG) is one of the key metabolites that play a crucial role in cellular energy metabolism. Bariatric surgery is a life-saving procedure, but it carries many gastrointestinal side effects. The present study investigated the beneficial effects of dietary AKG on the structure, integrity, and absorption surface of the small intestine after bariatric surgery. Male 7-week-old Spragu