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A more generalized fear response after a daytime nap

The aim of this study was to examine how a daytime nap affected the consolidation of fear learning. Participants first underwent fear conditioning during which they were exposed to a large and a small circle. One of these was repeatedly paired with an electric shock (making it the CS+), whereas the other circle was never paired with the shock (the CS−). After a delay interval containing either a n

On Goal Oriented Time Adaptivity using Local Error Estimates

We consider adaptive time discretization methods for ordinary differential equations where one aims to control the error in a quantity of interest of the form J(u) = ∫ j(u(t))dt with j : Rd -> R. In this setting we propose a new timestep controller based on local error estimates of the quantity of interest. The new method converges when the tolerance goes to zero.We experimentally compare the new

Assessing the effect of d-xylose on the sugar signaling pathways of Saccharomyces cerevisiae in strains engineered for xylose transport and assimilation

One of the challenges of establishing an industrially competitive process to ferment lignocellulose to value-added products using Saccharomyces cerevisiae is to get efficient mixed sugar fermentations. Despite successful metabolic engineering strategies, the xylose assimilation rates of recombinant S. cerevisiae remain significantly lower than for the preferred carbon source, glucose. Previously, One of the challenges of establishing an industrially competitive process to ferment lignocellulose to value-added products using Saccharomyces cerevisiae is to get efficient mixed sugar fermentations. Despite successful metabolic engineering strategies, the xylose assimilation rates of recombinant S. cerevisiae remain significantly lower than for the preferred carbon source, glucose. Previously,

The APSES protein Sok2 is a positive regulator of sporulation in Ashbya gossypii.

Ashbya gossypii is a homothallic, flavinogenic, filamentous ascomycete that starts overproduction of riboflavin and fragments its mycelium quantitatively into spore producing sporangia at the end of a growth phase. Mating is not required for sporulation and the standard homothallic laboratory strain is a MATa strain. Here we show that ectopic expression of Saccharomyces cerevisiae MATα2 in A. gossAshbya gossypii is a homothallic, flavinogenic, filamentous ascomycete that starts overproduction of riboflavin and fragments its mycelium quantitatively into spore producing sporangia at the end of a growth phase. Mating is not required for sporulation and the standard homothallic laboratory strain is a MATa strain. Here we show that ectopic expression of Saccharomyces cerevisiae MATα2 in A. goss

The functional 3′-end of immunoglobulin heavy chain variable (IGHV) genes

Inference of antibody gene repertoires using transcriptome data has emerged as an alternative approach to the complex process of sequencing of adaptive immune receptor germline gene loci. The diversity introduced during rearrangement of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes has however been identified as potentially affecting inference specificity. In this study,

Proton pump inhibitor medication is associated with colonisation of gut flora in the oropharynx

BACKGROUND: The normal body exists in mutualistic balance with a large range of microbiota. The primary goal of this study was to establish whether there is an imbalance in the oropharyngeal flora early after hospital or ICU admittance, and whether flora differs between control, ward and critically ill patients. The secondary goal was to explore whether there are patient characteristics that can b

BEHAVIOURAL IMPLICATIONS OF EMPLOYEE-DRIVEN INNOVATION — A CRITICAL DISCOURSE ANALYSIS

This paper examines a digital employee-oriented innovation program at a global IT-firm. It addresses the research question: how is the generation and promotion of employee ideas organised by the management, and what are the behavioural implications in terms of participation of such an organising? Drawing on the literature on inclusive innovation and employee-driven innovation, the authors explore

Estimation of event related potentials with GSVD

An algorithm for estimation of event related signals dis-turbed by coloured noise, e.g. Evoked Potentials disturbed byEEG, has been investigated. The method is based on GeneralSingular Value Decomposition, GSVD, and estimates a singleEvoked Potential without averaging. There are no assumptionsabout the model for the EEG. The EP is described as a sum ofdamped sinusoids. The algorithm is tested with

Optimization Methods for 3D Reconstruction : Depth Sensors, Distance Functions and Low-Rank Models

This thesis explores methods for estimating 3D models using depth sensors andfinding low-rank approximations of matrices. In the first part we focus on how toestimate the movement of a depth camera and creating a 3D model of the scene.Given an accurate estimation of the camera position, we can produce dense 3Dmodels using the images obtained from the camera. We present algorithms thatare both accu

Muscle function is associated with future patient-reported outcomes in young adults with ACL injury

BACKGROUND/AIM: Consequences of an anterior cruciate ligament (ACL) injury include worse patient-reported outcomes (PROs) and a decrease in activity level. Muscle function can be improved by targeted exercise. Our aims were to investigate cross-sectional and longitudinal associations among lower extremity muscle function and PROs after ACL injury.METHODS: Fifty-four participants (15 women, mean 30

Lean ApoM−/− Mice with Hyperactive Brown Adipose Tissue

In Cell Reports, Christoffersen et al. [1] demonstrate that sphingosine 1-phosphate (S1P) bound to apolipoprotein M (apoM) regulates the activity and mass of brown adipose tissue (BAT). They found mice lacking apoM to have hyperactive BAT with high triglyceride (TG) utilization, resulting in low white adipose tissue (WAT) mass and low body weight.

Search for W W/W Z resonance production in ℓνqq final states in pp collisions at √s=13 TeV with the ATLAS detector

A search is conducted for new resonances decaying into a W W or W Z boson pair, where one W boson decays leptonically and the other W or Z boson decays hadronically. It is based on proton-proton collision data with an integrated luminosity of 36.1 fb−1 collected with the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of s=13 TeV in 2015 and 2016. The search is sensitive to

Improved isolation of cadmium from paddy soil by novel technology based on pore water drainage with graphite-contained electro-kinetic geosynthetics

Novel soil remediation equipment based on electro-kinetic geosynthetics (EKG) was developed for in situ isolation of metals from paddy soil. Two mutually independent field plot experiments A and B (with and without electric current applied) were conducted. After saturation using ferric chloride (FeCl3) and calcium chloride (CaCl2), soil water drainage capacity, soil cadmium (Cd) removal performanc