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Terpenoid emissions from fully grown east Siberian Larix cajanderi trees

While emissions of many biogenic volatile organic compounds (BVOCs), such as terpenoids, have been studied quite intensively in North American and Scandinavian boreal forests, the vast Siberian boreal forests have remained largely unexplored by experimental emission studies. In this study the shoot-scale terpenoid emission rates from two mature Larix cajanderi trees growing in their natural habita

Prolonged dormancy interacts with senescence for two perennial herbs

Senescence is characterized by a decline in survival, fecundity and reproductive value with age among adult individuals. Simple age-dependent life cycles progress forward through developmental stages, with each successive stage being characterized by age-specific vital rates. In contrast, size- or stage-based life cycles for perennial plants are more complex and often include stasis and retrogress

Fine-Scale Mapping of the FGFR2 Breast Cancer Risk Locus: Putative Functional Variants Differentially Bind FOXA1 and E2F1

The 10q26 locus in the second intron of FGFR2 is the locus most strongly associated with estrogen-receptor-positive breast cancer in genome-wide association studies. We conducted fine-scale mapping in case-control studies genotyped with a custom chip (iCOGS), comprising 41 studies (n = 89,050) of European ancestry, 9 Asian ancestry studies (n = 13,983), and 2 African ancestry studies (n = 2,028) f

DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status.

We assessed DNA methylation and copy number status of 27,000 CpGs in 149 urothelial carcinomas and integrated the findings with gene expression and mutation data. Methylation was associated with gene expression for 1,332 CpGs, of which 26% showed positive correlation with expression, i.e., high methylation and high gene expression levels. These positively correlated CpGs were part of specific tran

Failure matters: unsuccessful cytogenetics and unperformed cytogenetics are associated with a poor prognosis in a population-based series of acute myeloid leukaemia.

Unsuccessful cytogenetics (UC) in acute myeloid leukaemia (AML) patients treated on different SWOG trials was recently reported to be associated with increased age and dismal outcome. In order to ascertain whether this holds true also in unselected AML patients, we retrieved all cytogenetic reports in cases from the population-based Swedish AML Registry. Between 1997 and 2006, 1737 patients below

Positive Effects of a Musculoskeletal Pain Rehabilitation Program Regardless of Pain Duration or Diagnosis.

OBJECTIVES: To investigate how sociodemographic and clinical factors are associated with psychosocial functioning and disability at admission to a musculoskeletal pain rehabilitation program and at 1-year follow-up. DESIGN: A cohort pre-post study. SETTING: A University hospital specialized pain rehabilitation unit. PARTICIPANTS: Five hundred nine participants with musculoskeletal pain (neck d

On image sensor dynamic range utilized by security cameras

The dynamic range is an important quantity used to describe an image sensor. Wide/High/Extended dynamic range is often brought forward as an important feature to compare one device to another. The dynamic range of an image sensor is normally given as a single number, which is often insufficient since a single number will not fully describe the dynamic capabilities of the sensor. A camera is ideall

IFPA Meeting 2010 Workshops Report II: Placental pathology; Trophoblast invasion; Fetal sex; Parasites and the placenta; Decidua and embryonic or fetal loss; Trophoblast differentiation and syncytialisation

Workshops are an important part of the IFPA annual meeting. At IFPA Meeting 2010 diverse topics were discussed in twelve themed workshops, six of which are summarized in this report. 1. The placental pathology workshop focused on clinical correlates of placenta accreta/percreta. 2. Mechanisms of regulation of trophoblast invasion and spiral artery remodeling were discussed in the trophoblast invas

Distribution and risk of the second discordant primary cancers combined after a specific first primary cancer in German and Swedish cancer registries.

We aimed at investigating the distribution and risk of all second discordant primary cancers (SDPCs) after a specific first primary cancer in Germany and Sweden to provide etiological understanding of SDPCs and insight into their incidence rates and recording practices. Among 1,537,004 survivors of first primary cancers in Germany and 588,103 in Sweden, overall 80,162 and 32,544 SDPCs were recorde

Search for heavy lepton resonances decaying to a Z boson and a lepton in pp collisions at root s=8 TeV with the ATLAS detector

A search for heavy leptons decaying to a Z boson and an electron or a muon is presented. The search is based on pp collision data taken at root s = 8TeV by the ATLAS experiment at the CERN Large Hadron Collider, corresponding to an integrated luminosity of 20.3 fb(-1). Three high-transverse-momentum electrons or muons are selected, with two of them required to be consistent with originating from a

Dominant impact of water exchange and disruption of stratification on dinoflagellate vertical distribution

The vertical positions of four dinoflagellate species in three 48 h periods in late summer in a Swedish fjord (the Gullmar Fjord) reflect changes to the depth of the halocline. During stable, stratified conditions, the chlorophyll a maximum exhibited a diurnal migration pattern, which was disrupted when the halocline was forced closer to the surface by the inflow of more saline water. While condit

Invasive plant species in the Swedish flora: developing criteria and definitions, and assessing the invasiveness of individual taxa

In a north European context, identifying invasive species is far from trivial because the vegetation has been influenced by human activities for thousands of years. New species have immigrated continuously since the end of the last glaciation, both spontaneously and through direct or indirect help by man. Still, newly immigrated species may be problematic in a nature conservation context and may h

Two-hundredfold volume concentration of dilute cell and particle suspensions using chip integrated multistage acoustophoresis.

Concentrating cells is a frequently performed step in cell biological assays and medical diagnostics. The commonly used centrifuge exhibits limitations when dealing with rare cell events and small sample volumes. Here, we present an acoustophoresis microfluidic chip utilising ultrasound to concentrate particles and cells into a smaller volume. The method is label-free, continuous and independent o

Photoemission studies of water dissociation on rutile TiO2 (110): Aspects on experimental procedures and the influence of steps

composition of the first water layer on the stoichiometric rutile TiO2 (1 1 0) surface was studied with the use of synchrotron radiation photoelectron spectroscopy. The same H2O-OH balance was reached using different preparation procedures and there was no difference between H2O and D2O. On this basis, we rule out the possibility that the partially dissociated layer is an artifact caused by photon

Adopted children with cleft lip or palate, or both, require special needs cleft surgery.

In recent years adoption of children with cleft lip, with or without cleft palate (CLP), and other birth defects has become more common. The aim of the present study was to describe the characteristics and initial care and treatment of adopted children with CLP. A total of 25 children were referred to our department between 2008 and 2010, 7 (28%) of whom had bilateral CLP and 16 (64%) had unilater

Enzymatic oil extraction and positional analysis of omega-3 fatty acids in Nile perch and salmon heads

The use of commercial proteases, bromelain and Protex 30L for oil extraction/recovery of polyunsaturated fatty acids (PUFA) from Nile perch and salmon heads was evaluated. Four phases were obtained after hydrolysis, oily phase, emulsion, aqueous phase and sludge. An increase in water content during the hydrolysis resulted in a decrease in oil yield. Maximum oil yield was obtained when hydrolysis w

Production of arabinoxylan-oligosaccharide mixtures of varying composition from rye bran by combination of process conditions and type of xylanase.

The aim was to study arabinoxylan-oligosaccharide production from rye bran using heat pretreatment and enzymatic hydrolysis. Due to the potential application in foods, the purity of arabinoxylan was also assessed. Rye bran was heat pretreated to improve xylanase-catalyzed hydrolysis of arabinoxylan into arabinoxylan-oligosaccharides. Enzymatic removal of starch and proteins before or after heat pr

Role of exosomes and microvesicles in hypoxia-associated tumour development and cardiovascular disease.

Exosomes and microvesicles, collectively referred to as extracellular vesicles (EVs), can transfer complex biological information and induce a diverse signalling response in recipient cells with potential relevance in a wide array of pathological conditions. Tissue hypoxia constitutes a stress-associated phenotype that is central to the malignant state of aggressive tumours as well as to ischaemic