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Studies on Thiol-Disulfide Oxidoreductases in Bacillus subtilis

Popular Abstract in Swedish Bacillus subtilis är en modellorganism för endosporbildande bakterier. Endosporen är ett vilostadium som kan bildas av vissa bakteriarter vid svält. Endosporer är mycket tåliga. De kan t.ex. överleva extrem värme, UV-strålning, uttorkning och farliga kemikalier utan att skadas. När tillgången på näring på nytt kan tillåta växt av bakterien, kan endosporen germinera och Bacillus subtilis is a model organism for endospore-forming gram-positive bacteria. Endospores are formed in response to nutrient starvation. They can resist harsh environments and last for long periods of time. Once nutrients again become available, the endospore can germinate and the vegetative life cycle be resumed. The outermost layers of the endospore are cortex and coat that protect the cell

The role of B cells and Th2 cytokines in physiological and pathological inflammation

Popular Abstract in Swedish Vårt immunförsvar har utvecklats genom evolutionen för att kunna motstå infektioner från diverse mikrober (parasiter, bakterier, virus). Kroppen svarar då med en inflammationsrespons för att kunna bekämpa infektionen. Immunsvaret kan delas upp i det icke specifika immunsvaret, bestående av bl.a. fagocyterande celler samt det specifika immunsvaret, bestående av sk T och The CD4+ T cells have an important role in inflammation. Based on the local cytokine milieu, these cells can differentiate into either a Th1 population promoting cellular immunity or Th2 population involved in humoral immunity. Th2 cells produce the anti-inflammatory cytokines IL-4 and IL-10, which might have a protective role in autoimmune diseases like rheumatoid arthritis (RA) and multiple scle

Att förstå mänsklig handling : Slutrapport från ett forskningsprogram

Genom Stiftelsen Riksbankens Jubileumsfonds forskningsprogram "Att förstå mänsklig handling" finns det nu för första gången en storskalig filosofihistorisk tematisering av föreställningar om handling och aktörskap från antiken till tidigmoderna och moderna filosofer. Varken i Skandinavien eller i en större internationell kontext har något liknande genomförts tidigare. Denna skrift är programmets s

Resource economy of carnivorous plants: Interactions between prey capture and plant performance in three subarctic Pinguicula species

Popular Abstract in Swedish I min avhandling har jag studerat resursekonomin hos tre köttätande växter i fjällen. Arterna var vanlig tätört (Pinguicula vulgaris), fjälltätört (P. alpina) och dvärgtätört (P. villosa). Alla försöken var utförda i fält. Bytesfångsten varierade mellan individuella plantor, år och arter. Ynga blad fångade mer byten än gamla. Vanlig tätört fångade fler byten än de andraIn this thesis, I have studied in situ the resource economy of the three carnivorous plant species Pinguicula alpina, P. villosa and P. vulgaris in a subarctic environment. The prey capture varied among individual plants, years and species. It was higher in young leaves then in old ones. P. vulgaris captured more prey that the other species and reproductive individuals of P. vulgaris captured more

Improving distance estimates to nearby bright stars: Combining astrometric data from Hipparcos, Nano-JASMINE and Gaia

Starting in 2013, Gaia will deliver highly accurate astrometric data, which eventually will supersede most other stellar catalogues in accuracy and completeness. It is, however, limited to observations from magnitude 6 to 20 and will therefore not include the brightest stars. Nano-JASMINE, an ultrasmall Japanese astrometry satellite, will observe these bright stars, but with much lower accuracy. H

On interactions between Packaging and Logistics - Exploring implications of technological developments

Packaging is a fundamental element in logistics systems. Packaging not only affects every logistical activity; it is also recognised as having a significant impact on logistics costs and performance. In order for logisticians and packaging professionals to gain insight into packaging-dependent costs and performance, the interactions between packaging systems and logistics systems must be understoo

Overview of the MPEG Reconfigurable Video Coding Framework

Abstract in UndeterminedVideo coding technology in the last 20 yearshas evolved producing a variety of different and com-plex algorithms and coding standards. So far the speci-fication of such standards, and of the algorithms thatbuild them, has been done case by case providingmonolithic textual and reference software specifica-tions in different forms and programming languages.However, very littl

Mechanisms of Brain Damage Following Focal Cerebral Ischemia: Changes in Ion Homeostasis and the Importance of Free Radical Formation

Popular Abstract in Swedish Svensk sammanfattning Slaganfall (stroke), hjärtstillestånd eller överdosering av insulin är tillstånd som leder till en minskning av syre- och/eller glukos till hjärnvävnaden. Då tillförseln av glukos och syrgas minskar, kan cellerna inte längre upprätthålla en normal energiproduktion. Eftersom en stor del av energin går åt till bevara den spänning som finns över cellIn this thesis mechanisms of neuronal damage were investigated in an experimental stroke model i.e focal ischemia. The influence of SD-induced calcium transients on neuronal damage were studied in animals with reduced energy supply. The influence of bioenergetic failure on K+e concentration and Ca2+e homeostasis were also investigated in transient focal ischemia. Moreover, the free radical formati

Statistical Physics of Protein Folding and Aggregation

The mechanisms of protein folding and aggregation are investigated by computer simulations of all-atom and reduced models with sequence-based potentials. A quasi local Monte Carlo update is developed in order to efficiently sample proteins in the folded phase. A small helical protein, the B-domain of staphylococcal protein A, is studied using a reduced model. In the thermodynamically favoured topo

On the Value of Pictures in Verbal Cognition

Popular Abstract in Swedish Syftet med avhandlingen var att analysera värdet av bilder i ett antal kognitiva uppgifter som framförallt är av verbal natur. Avhandlingen omfattar tre studier, med vardera tre experiment. I den första studien visades automatiskt inflytande från bilder (ansiktsuttryck) på en affektiv bedömning av ord som positiva eller negativa. I den integrerade presentationen av ord The aim of this thesis was to analyze the value of pictures in a number of cognitive tasks that are predominantly verbal in nature. Three studies, with three experiments each, are included in the thesis. The first study found automatic interference effects from pictures (facial expressions) on the affective evaluation of words. In the Stroop-like presentation of integrated picture-and-word stimuli