Antibodies play a central role in the immune defense against SARS-CoV-2. Emerging evidence has shown that nonneutralizing antibodies are important for immune defense through Fc-mediated effector functions. Antibody subclass is known to affect downstream Fc function. However, whether the antibody subclass plays a role in anti-SARS-CoV-2 immunity remains unclear. Here, we subclass-switched eight hum

We coordinate interconnected agents where the control input of eachagent is limited by the control input of others. In that sense, the sys-tems have to share a limited resource over a network. Such problems canarise in different areas and it is here motivated by a district heating ex-ample. When the shared resource is insufficient for the combined needof all systems, the resource will have to be s

INTRODUCTION Worldwide every third women is exposed to physical and/or sexual violence and pregnancy is no safe period for the women. The aim was to elucidate midwives experience of violence-exposed pregnant women who had been referred to a prenatal ward and were hospitalized. METHODS An inductive qualitative method was used with four focus-group interviews performed with sixteen midwives working

MUC5B is the predominant glycoprotein in saliva and is instrumental in the establishment and maintenance of multi-species eubiotic biofilms in the oral cavity. Investigations of the aciduric Lactobacillaceae family, and its role in biofilms emphasizes the diversity across different genera of the proteolytic systems involved in the nutritional utilization of mucins. We have characterized a protease

Patients with cardiac implantable electronic device (CIED) and Staphylococcus aureus bacteraemia (SAB) are at risk of having infective endocarditis (IE). The objectives were to describe a Swedish population-based cohort of patients with CIED and SAB, to identify risk factors, and to construct a predictive score for IE. Patients over 18 years old in the Stockholm Region identified to have SAB in th

Introduction: The definition of asthma phenotypes has not been fully established, neither there are cluster studies showing homogeneous results to solidly establish clear phenotypes. The purpose of this study was to develop a classification algorithm based on unsupervised cluster analysis, identifying clusters that represent clinically relevant asthma phenotypes that may share asthma-related outco

Avhandlingen är en studie av hur stöd och service organiseras kring fyra barn med funktionshinder och deras familjer. I denna service är normalt flera olika formella organisationer involverade, som barnhabilitering, förskola/skola/särskola, hjälpmedelscentral, assistentorganisationer, sjukvård m fl. Dessutom kan barnets och familjens situation vara komplicerad på många sätt. Själva funktionshindreThis study explores the organising of services for disabled children and their families in Sweden. It is based on 83 interviews with parents and involved staff surrounding four disabled children, with both physical and intellectual disabilities, and between two and nine years old. Further, 15 meetings between parents and staff were observed, primarily serving as background material. The service pr

Vassiliki “Betty” Smocovitis has done a thorough and admirable job in highlighting the complex history the Modern Synthesis (MS) or the Evolutionary Synthesis (ES) as she prefers to call it. Her interesting contribution should hopefully increase awareness that the history of evolutionary biology is important even for researchers today who are mainly interested in solving practical questions of mor

Covid-19 increased the social and economic vulnerability of island societies. Swedish islands are key tourism destinations but are also home to many island residents. Previous studies have high-lighted the impact of Covid-19 on core areas, but our knowledge of its impact on island communities is lac-king. We use phenomenology to analyse how communities in small Swedish islands perceive the impact

The ATLAS physics program at the High Luminosity LHC (HL-LHC) calls for a precision in the luminosity measurement of ±1%. A larger uncertainty would represent the dominant systematic error in some precision measurements, including the Higgs sector. To fulfil such requirement in an environment characterized by up to 140 simultaneous interactions per bunch crossing (200 in the ultimate scenario), AT

Quark spin effects in hadronization have been recently included in the PYTHIA 8 event generator for the simulation of the deep inelastic scattering (DIS) process off a polarized nucleon target via the external StringSpinner package. The spin effects can be simulated for the production of pseudoscalar mesons using the string+3P0 model of polarized quark fragmentation and parametrizations of the tra

BACKGROUND: Whether sex-specific differences exist for risk factors for pulmonary embolism (PE) and deep venous thrombosis (DVT), with the exception of pregnancy and estrogen therapy, has been sparsely studied. We aimed to study whether sex-specific differences of risk factors exist for noncancer-related DVT and PE in middle-aged and older individuals without cardiovascular history or previous dia

(1) Background: This study examined the cross-sectional association between metabolic syndrome (MetS) status classified into three groups and daily physical activity (PA; step count and active minutes) using a wearable device in Japanese office workers. (2) Methods: This secondary analysis used data from 179 participants in the intervention group of a randomized controlled trial for 3 months. Indi

We discuss our recent results on azimuthal distributions in vector boson + jets and multi-jet production at the LHC, obtained from the matching of next-to-leading order (NLO) perturbative matrix elements with transverse momentum dependent (TMD) parton branching. We present a comparative analysis of boson-jet and jet-jet correlations in the back-to-back region, and a study of the theoretical system

We go beyond the state-of-the-art by combining first principal lattice results and effective field theory approaches as Polyakov Loop model to explore the non-perturbative dark deconfinement-confinement phase transition and the generation of gravitational-waves in a dark Yang-Mills theory. We further include fermions with different representations in the dark sector. Employing the Polyakov-Nambu-J

Totally ramified rational maps and regularly ramified rational maps are defined and studied in this paper. We first give a complete classification of regularly ramified rational maps and show that our definition of a regularly ramified rational map is equivalent to a much stronger definition of a map of this kind given by Milnor [Dynamics in one complex variable, Princeton University Press, Prince