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Underlying conditions contributing to breathlessness in the population

PURPOSE OF REVIEW: Assessment of underlying conditions that contribute to breathlessness is fundamental for symptom management. This review aims to summarize the knowledge from the past two years on the most common underlying conditions among individuals with breathlessness in the general population and to identify research gaps. RECENT FINDINGS: Nine studies from the last two years were included

Contrasting effects of tree origin and urbanization on invertebrate abundance and tree phenology

The ongoing wide-scale introduction of nonnative plants across the world may negatively influence native invertebrate fauna, due to a lack of coevolved traits related to the novel plants, e.g., unique phytochemicals or shifted phenology. Nonnative plants, specifically trees, are common in urban environments, areas that already pose novel habitats to plants and wildlife through a wide array of anth

The Politics of Diversity in Music Education

This open access book examines the political structures and processes that frame and produce understandings of diversity in and through music education. Recent surges in nationalist, fundamentalist, protectionist and separatist tendencies highlight the imperative for music education to extend beyond nominal policy agendas or wholly celebratory diversity discourses. Bringing together high-level the

Caught between principles and politics : Challenges and opportunities for capacity development from governmental donors’ perspectives

Capacity development —an integral part of development cooperation in general and for disaster risk reduction (DRR) in particular—has had limited success so far. This article investigates capacity development challenges and opportunities from the viewpoint of the staff of progressive governmental donor agencies. Data were obtained from 26 semi-structured interviews with informants from seven donor

Life cycle assessment for identification of critical aspects in emerging technologies for the extraction of phenolic compounds from spruce bark

Polyphenolic compounds in bark are resources of great interest to produce renewable chemicals and several different technologies are available or under early development for the extraction of these types of compounds. Since critical environmental effects of a product are often set during the design phase, it is important to use life cycle assessment (LCA) to identify the steps resulting in the lar

Neutrophils Lose the Capacity to Suppress T Cell Proliferation Upon Migration Towards Inflamed Joints in Juvenile Idiopathic Arthritis

Neutrophils are highly abundant in synovial fluid of rheumatic inflamed joints. In oligoarticular juvenile idiopathic arthritis (JIA), synovial fluid neutrophils have impaired effector functions and altered phenotype. We hypothesized that these alterations might impact the immunoregulatory interplay between neutrophils and T cells. In this study we analyzed the suppressive effect of neutrophils, i

CEACAM5, KLK6, SLC35D3, POSTN, and MUC2 mRNA Analysis Improves Detection and Allows Characterization of Tumor Cells in Lymph Nodes of Patients Who Have Colon Cancer

BACKGROUND: Lymph node metastasis is the single most important prognostic risk factor for recurrence in patients with colon cancer who have undergone curative surgery. The routine method for detecting disseminated tumor cells in lymph nodes is microscopic examination of one or a few hematoxylin and eosin-stained tissue sections by a trained pathologist. This method, however, is insensitive mainly

A sustainability index within water and wastewater management in Sweden : An evaluation of eight case studies

A sustainability index (SI) is a benchmark for guiding the activities of municipal water and wastewater (W and WS) utilities toward sustainability. The SI has been used in Sweden since 2014 as an internal benchmark management tool facilitating the strategic work of organizations. This study assesses how the SI was applied in practice by eight utilities (Orgs 1–8) from 2015 to 2019. The study was p

Health-Related Quality of Life in Children With Earlier Surgical Repair for Right Ventricular Outflow Tract Anomalies and the Agreement Between Children and Their Parents

Background: Children diagnosed with right ventricle outflow tract (RVOT) anomalies require surgical repair early in life, reoperations and lifelong follow-up. The aim is to comprehensively describe their health related quality of life (HRQoL) and to assess the agreement in this regard between children and parents. Methods and Results: Child- and parent-reported HRQoL was assessed in 97 children ag

The business model in sustainability transitions : A conceptualization

Business models direct a firm’s activity to move in coherence with the objectives of the business. Current literature suggests business models can act as vital forces to facilitate sustain-ability transitions and highlights the urgent research call to understand the role of business model innovations in stimulating sustainability transitions. This paper addresses this research need by investigatin

PCprophet : a framework for protein complex prediction and differential analysis using proteomic data

Despite the availability of methods for analyzing protein complexes, systematic analysis of complexes under multiple conditions remains challenging. Approaches based on biochemical fractionation of intact, native complexes and correlation of protein profiles have shown promise. However, most approaches for interpreting cofractionation datasets to yield complex composition and rearrangements betwee