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Extending the Relay Feedback Experiment

An augmented version of the traditional relay feedback experiment is proposed. It aims at producing an input with energy concentrated to a frequency band, corresponding to a certain phase sector of the Nyquist curve of the process to be identified. A non-convex problem is formulated. Sub-optimal, but efficient, algorithms are developed.

Building shared identities in a radio counseling programme's Internet forum

The paper reports a study of a radio counselling program broadcast once a week on a Swedish state radio channel. The program episodes consist of telephone conversations between a psychotherapist and persons seeking help in dealing with life’s troubles such as difficulties in relations between parents and children or between spouses, coping with anxiety, overcoming traumatic childhood experiences o

Right precordial-directed electrocardiographical markers identify arrhythmogenic right ventricular cardiomyopathy in the absence of conventional depolarization or repolarization abnormalities

Background: Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) carries a risk of sudden death. We aimed to assess whether vectorcardiographic (VCG) parameters directed toward the right heart and a measured angle of the S-wave would help differentiate ARVD/C with otherwise normal electrocardiograms from controls. Methods: Task Force 2010 definite ARVD/C criteria were met for all pat

Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread : A case control study

Background: Metastases from primary breast cancers can involve single or multiple organs at metastatic disease diagnosis. Molecular risk factors for particular patterns of metastastic spread in a clinical population are limited. Methods: A case-control design including 1357 primary breast cancers was used to study three distinct clinical patterns of metastasis, which occur within the first six mon

Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

Relapse is a major problem in acute myeloid leukemia (AML) and adversely affects survival. In this phase 2 study, we investigated the effect of vaccination with dendritic cells (DCs) electroporated with Wilms’ tumor 1 (WT1) messenger RNA (mRNA) as postremission treatment in 30 patients with AML at very high risk of relapse. There was a demonstrable antileukemic response in 13 patients. Nine patien

Colorectal cancer-infiltrating T lymphocytes display a distinct chemokine receptor expression profile

Background: T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, whereas in case of colorectal cancer (CRC), infiltration of T lymphocytes into the tumor is crucial for an effective anti-tumor immune response. In both situations, the recruitment mechanisms of T lymphocytes into the tissues are essential for the immunological functions deciding the outcome. The recr

Long-Term Follow-Up of Retromuscular Incisional Hernia Repairs : Recurrence and Quality of Life

Purpose: Incisional hernia repair (IHR) with a mesh is necessary to achieve low recurrence rates and pain relief. In the short term, quality of life (QoL) is restored by IHR. Two centers pioneered the IHR in Sweden with the highly standardized Rives–Stoppa technique using a retromuscular mesh. We assessed long-term follow-up of recurrence rate and QoL. Methods: Medical records were searched for IH

Using Floodwater for Artificial Recharge and Spate Irrigation

Floodwater harvesting (FWH) for artificial recharge of groundwater (ARG) and spate irrigation (SI) is the most widely practiced large catchment water harvesting technique. It has recently received renewed attention for research, improvement, and implementation. This chapter first introduces an innovative, locally adaptive, and improved FWH technique—floodwater spreading systems (FWS)—to guide poli

The LeucoPatch® system in the management of hard-to-heal diabetic foot ulcers : Study protocol for a randomised controlled trial

Background: Diabetic foot ulcers are a common and severe complication of diabetes mellitus. Standard treatment includes debridement, offloading, management of infection and revascularisation where appropriate, although healing times may be long. The LeucoPatch® device is used to generate an autologous platelet-rich fibrin and leucocyte wound dressing produced from the patient's own venous blood by

Resistance to activated protein C as an additional genetic risk factor in hereditary deficiency of protein S

Inherited resistance to activated protein C (APC), which is caused by a single point mutation in the gene for factor V, is a common risk factor for thrombosis. In this study, the prevalence of APC resistance in 18 unrelated thrombosis-prone families with inherited protein S deficiency was investigated to determine its role as additional genetic risk factor for thrombosis. In addition, a detailed e