Mechanism of amyloid protein aggregation and the role of inhibitors
Inhibition of amyloid β peptide (Aβ) aggregation is an important goal due to the connection of this process with Alzheimer's disease. Traditionally, inhibitors were developed with an aim to retard the overall macroscopic aggregation. However, recent advances imply that approaches based on mechanistic insights may be more powerful. In such approaches, the microscopic steps underlying the aggregatio
