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The importance of time of day for magnetic body alignment in songbirds

Spontaneous magnetic alignment is the simplest known directional response to the geomagnetic field that animals perform. Magnetic alignment is not a goal directed response and its relevance in the context of orientation and navigation has received little attention. Migratory songbirds, long-standing model organisms for studying magnetosensation, have recently been reported to align their body with

Placental Tissue Destruction and Insufficiency from COVID-19 Causes Stillbirth and Neonatal Death from Hypoxic-Ischemic Injury : A Study of 68 Cases with SARS-CoV-2 Placentitis from 12 Countries

CONTEXT.—: Perinatal death is an increasingly important problem as the COVID-19 pandemic continues, but the mechanism of death has been unclear.OBJECTIVE.—: To evaluate the role of the placenta in causing stillbirth and neonatal death following maternal infection with COVID-19 and confirmed placental positivity for SARS-CoV-2.DESIGN.—: Case-based retrospective clinico-pathological analysis by a mu

Large gaps in the quality of healthcare experienced by Swedish mothers during the COVID-19 pandemic : A cross-sectional study based on WHO standards

Background and Problem: Existing healthcare systems have been put under immense pressure during the COVID-19 pandemic. Disruptions in essential maternal and newborn services have come from even high-income countries within the World Health Organization (WHO) European Region. Aim: To describe the quality of care during pregnancy and childbirth, as reported by the women themselves, during the COVID-

Social functioning and the presentation of anxiety in children on the autism spectrum: A multimethod, multiinformant analysis

Co-occurring anxiety in children on the autism spectrum is associated with greater social challenges, including poorer social skills and relationships, which may influence the severity and presentation of anxiety symptoms, particularly social anxiety. The current study used Bayesian network analytics (Williams & Mulder, 2020) and a multimethod approach to examine (a) how different facets of so

Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion

We previously reported that loss of mitochondrial transcription factor B1 (TFB1M) leads to mitochondrial dysfunction and is involved in the pathogenesis of type 2 diabetes (T2D). Whether defects in ribosomal processing impact mitochondrial function and could play a pathogenetic role in β-cells and T2D is not known. To this end, we explored expression and the functional role of dimethyladenosine tr

Market economy and urban change : Impacts in the developing world

Across the developing world the preceding decade or so has witnessed a profound reconfiguration of the political economy of urban policy. This new policy environment is driven by globalization, the neo-liberal macro-economic package of 'market enablement' and structural adjustment, which now form the dominant development paradigm. The consequences of this approach for urban development agendas and

Integrated continuous biomanufacturing on pilot scale for acid-sensitive monoclonal antibodies

In this study, we demonstrated the first, to our knowledge, integrated continuous bioprocess (ICB) designed for the production of acid-sensitive monoclonal antibodies, prone to aggregate at low pH, on pilot scale. A high cell density perfusion culture, stably maintained at 100 × 106 cells/ml, was integrated with the downstream process, consisting of a capture step with the recently developed Prote

Microscopic and macroscopic simulation of early freight train departures

In Sweden and other countries it is not an uncommon practice that freight trains depart more or less on-demand instead of strictly following a pre-planned timetable. However, the systematic effects of freight trains departing late or (in particular) early has long been a contested issue. Although some microscopic simulation tools currently have the capability to evaluate the effect of freight trai

The South African Families Database

Very little is known about what family life looked like for settlers in colonial South Africa during the 18th or 19th century, nor how events over these centuries might have affected demographic change. The primary reason for this lacuna is a shortage of adequate data. Historians and genealogists have, over the last century, worked to combine the rich administrative records that are available in t