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Kardiovaskulär sjukdom och diabetes typ II som riskfaktorer för kognitiv sjukdom
En kort sammanställning i tidningen Neurolog i Sverige av våra två artiklar som presenterar prevalensen av kardiovaskulär sjukdom och typ 2 diabetes i olika kognitiva sjukdomar. Här visar vi att Alzheimer's sjukdom och Lewykroppssjukdom, de två vanligaste neurodegenerativa sjukdomarna, har en signifikant lägre förekomst av både kardiovaskulär sjukdom och typ 2 diabetes jämfört med vaskulär demens.Here we presented a review of our two articles presenting the prevalence of cardiovascular disease and diabetes in neurocognitive disorders; Alzheimer's disease, vascular dementia, mixed dementa and Lewy body disease. Cardiovascular disease and diabetes showed a significantly lower prevalence among cases with Alzheimer's disease and Lewy body disease, both neurodegenerative disorders, compared to
Tissue Repair Responses and Integrity of the Atherosclerotic Plaque
Introduction
The Nordic Militaries: forces for good?
β-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system
Increasing evidence links intraneuronal β-amyloid (Aβ 42) accumulation with the pathogenesis of Alzheimer's disease (AD). In Aβ precursor protein (APP) mutant transgenic mice and in human AD brain, progressive intraneuronal accumulation of Aβ42 occurs especially in multivesicular bodies (MVBs). We hypothesized that this impairs the MVB sorting pathway. We used the trafficking of the epidermal grow
Chaperones increase association of tau protein with microtubules
Molecular chaperones and their functions in protein folding have been implicated in several neurodegenerative diseases, including Parkinson's disease and Huntington's disease, which are characterized by accumulation of protein aggregates (e.g., α-synuclein and huntingtin, respectively). These aggregates have been shown in various experimental systems to respond to changes in levels of molecular ch
β-amyloid modulation of synaptic transmission and plasticity
Alzheimer's disease therapy : Focus on synapses
Apolipoprotein E, Aβ-amyloid, and the molecular pathology of Alzheimer's disease : Therapeutic implications
Neurogenesis as a therapeutic strategy for cognitive aging and Alzheimer's disease
Live discussion : From here to there: AβPP as an axonal transport receptor - How could this explain neurodegeneration in AD?
Occupational load as a risk factor for clinically relevant base of thumb osteoarthritis
Objective: It is postulated that increased load from pinch and grasp in occupational tasks increases the risk of thumb carpometacarpal (CMC1) osteoarthritis (OA). We sought to characterise the relationship between doctor-diagnosed CMC1 OA and occupation in a large working population. Methods: We performed a matched case-control study using a Swedish healthcare register. We identified residents age
Differences in phase transformation in laser peened and shot peened 304 austenitic steel
Laser Shock Peening (LSP) and Shot Peening (SP) are processes used to mechanically alter the surface properties of metals by inducing a transient high-pressure wave by a laser pulse or by a high-velocity impact of a peening particle. Both processes aim to induce compressive residual stresses near the surface and the level of residual stresses obtained from SP or LSP is similar. When austenitic steLaser Shock Peening (LSP) and Shot Peening (SP) are processes used to mechanically alter the surface properties of metals by inducing a transient high-pressure wave by a laser pulse or by a high-velocity impact of a peening particle. Both processes aim to induce compressive residual stresses near the surface and the level of residual stresses obtained from SP or LSP is similar. When austenitic ste
Inga Tidblad
Biografisk artikel om skådespelaren Inga Tidblad i Svenskt kvinnobiografiskt lexikon
Ett orättvist pensionssystem är också ohållbart
Investing in our Adolescents: Assertions of the 11th World Congress on Adolescent Health
Leisure in Late Capitalism
There is no apparent need for individuals to endure this kind of suffering in contemporary Western society with all its advantages. Nevertheless, endurance running is now a mainstream leisure pursuit. Why do hundreds of thousands of men, women and even children choose this torturous kind of leisure activity?In previous literature on consumption of extraordinary experiences, authors focus on the pu
Person-centred health systems: strategies, drivers and impacts
Understanding SSIM
The use of the structural similarity index (SSIM) is widespread. For almost two decades, it has played a major role in image quality assessment in many different research disciplines. Clearly, its merits are indisputable in the research community. However, little deep scrutiny of this index has been performed. Contrary to popular belief, there are some interesting properties of SSIM that merit suc