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Type 2 Diabetes (T2D) is a disease of increasing importance and represents a growing burden on global healthcare and human health. In T2D, loss of effectiveness of insulin signaling in peripheral tissues cannot be compensated for by adequate insulin secretion, leading to hyperglycemia and resultant complications. In recent years, inflammation has been identified as a central component of T2D, both

The use of cross-flow ultrafiltration for the recovery of coating material from aqueous streams started about 30 years ago with electro-deposition paint in the automotive industry. This early success can be related to both environmental and economical advantages of using ultrafiltration. Ultrafiltration recovers and concentrates electro-deposition paint on the retentate side and produces purified

Described is a method for preparing a purified liquid containing carbohydrates. The method comprises the steps of: hydrolysing starch to a dextrose equivalent (DE) of 10 or above, thus obtaining a liquid of carbohydrates; removing a heavy weight sludge fraction from the light weight liquid of carbohydrates using centrifugation; filtering the remaining liquid of carbohydrates, the filter being capa

An Eulerian Monte-Carlo approach, the so-called Eulerian stochastic fields (ESF) method is implemented and evaluated for simulation of non-premixed hydrogen/air combustion in supersonic flows. The ESF method is integrated into a compressible flow large eddy simulation (LES) solver, and validated on a supersonic combustor with a strut as flame-holder. Comparison with experimental data and with resu

Objective:This post-hoc analysis of the EDGE (Effectiveness of Diabetes control with vildaGliptin and vildagliptin/mEtformin) study assessed inter-regional differences in baseline characteristics and response to treatment intensification with dual oral antidiabetes drugs (OADs) in patients with type 2 diabetes mellitus (T2DM).Methods:Patients with T2DM inadequately controlled with first-line monot

Objective: The aim of this study was to create a preoperative prediction model predicting extraprostatic tumour growth in men with clinically organ-confined disease from a prospectively collected Swedish cohort. Materials and methods: The study used data from 3386 men in the prospective multi-centre Laparoscopic Prostatectomy Robot Open (LAPPRO) trial, with 14 participating urological departments.

We examined the association between unintentional nonhunting firearm deaths and changes in firearm legislation in Sweden. There were 43 fatalities during the study time frame 1983–2012, representing 46% of all unintentional firearm deaths during the same period. The victims were predominantly young males (mean age 25 years). Slightly more than half of the deaths were caused by another person and w

We describe a method and device (< 1.2 g) for recording, processing and storing data about activity and location of individuals of free-living songbirds throughout the annual cycle. Activity level was determined every five minutes from five 100 ms samples of accelerometer data with 5 s between the sampling events. Activity levels were stored on an hourly basis throughout the annual cycle, allowing

Time synchronization is crucial for wireless sensor networks (WSNs), where operations often rely on time ordering of events. WSNs are deployed in different scenarios, and therefore their timing requirements are often related to the peculiar characteristics of the specific environment they have to act in. Synchronization is anyway always an issue: transactional applications need monotonicity of the

Background: Recent studies suggest a possible causal role for smoking in schizophrenia and psychosis. Most studies have focused on cigarette smoking, the most common form of tobacco use, but other forms of tobacco exist, including smokeless products such as Swedish snuff (or "snus"). Methods: We explored whether snus use is associated with schizophrenia and non-affective psychotic illness in a lar

Fluvial export of organic matter from the terrestrial catchment to the aquatic system is a large and increasing carbon flux. The successful reduction in sulfuric acid deposition since the 1980s has been shown to enhance the mobility of organic matter in the soil, with more terrestrially derived dissolved organic matter (DOM) reaching aquatic systems. Changes in soil acidity also affect the quality

I argue that Mumford and Anjum’s recent theory of simultaneous causation among powerful meso-level objects is problematic in several respects: it is based on a false dichotomy, it is incompatible with standard meso-level physics, it is explanatory deficient, and it threatens to render the powers metaphysics incoherent. Powers theorists are advised, therefore, to adopt a purely sequential conceptio