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Regulating Quantum Computers: Insights into early patterns and trends in academic regulatory conversations on 'Quantum Revolution'

These days, talk of quantum technologies and the coming “quantum revolution” or “quantum leap” is hard to miss. There is a broad agreement that quantum technologies have a high probability of becoming the next disruptive technological development, and the way they should be regulated and the timing of such intervention are issues that are attracting increasing attention. An analysis of how these q

Design optimisation methodology of a high-speed switched reluctance motor for automotive traction applications

This paper forms part of a broader study on the design and optimisation of a high speed switched reluctance motor (SRM) for hybrid-electrical automotive traction applications. The main focus of this particular paper is to explain the design optimisation methodology followed. Furthermore, the main aim of the motor design is to push the power density of the SRM as high as possible. This leads to num

Automated spectrometer alignment via machine learning

During beam time at a research facility, alignment and optimization of instrumentation, such as spectrometers, is a time-intensive task and often needs to be performed multiple times throughout the operation of an experiment. Despite the motorization of individual components, automated alignment solutions are not always available. In this study, a novel approach that combines optimisers with neura

Performance Analysis of Centrifugal Compressor Stage using Detailed Component Level Measurements

This paper deals with the component level breakdown of performance characteristics of a centrifugal compressor using detailed measurements. The compressor stage used for Heavy-Duty applications consisting of the impeller, vaneless diffuser, and volute has been experimentally tested in a gas stand. Several static pressure measurements combined with total pressure and temperature measurements on the

Can Urinary Bladder Innervation Be Restored After Outlet Obstruction and Denervation?

Transurethral resection of the prostate, or other methods to decrease outlet resistance usually leads to relief of symptoms in patients with bladder outlet obstruction (BOO). If symptoms of underactivity persist after normalization of outflow conditions, treatment options are limited. In this review, we hypothesize, based on results from basic research, what might become treatment options for such

Generating gravitational waveform libraries of exotic compact binaries with deep learning

Current gravitational wave (GW) detections rely on the existence of libraries of theoretical waveforms. Consequently, finding new physics with GWs requires libraries of nonstandard models, which are computationally demanding. We discuss how deep learning frameworks can be used to generate new waveforms "learned"from a simulation dataset obtained, say, from numerical relativity simulations. Concret

Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model

INTRODUCTION: Tau-positron emission tomography (PET) outcome data of patients with Alzheimer's disease (AD) cannot currently be meaningfully compared or combined when different tracers are used due to differences in tracer properties, instrumentation, and methods of analysis. METHODS: Using head-to-head data from five cohorts with tau PET radiotracers designed to target tau deposition in AD, we te

Tailored Dose-Dense Versus Standard Adjuvant Chemotherapy for High-Risk Early Breast Cancer: End-of-Study Results of the Randomized PANTHER Trial

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

Body mass index and risk of over 100 cancer forms and subtypes in 4.1 million individuals in Sweden : the Obesity and Disease Development Sweden (ODDS) pooled cohort study

BACKGROUND: Obesity, assessed by body mass index (BMI), is an established risk factor for 13 cancers. We aimed to identify further potential obesity-related cancers and to quantify their association with BMI relative to that of established obesity-related cancers.METHODS: Using Cox regression models on 4,142,349 individuals in Sweden (mean age 27.1 years at weight measurement), we calculated hazar

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Lisbeth Nilsson Summary presentation Kids Loco I am most thankful to meeting with sensai Junichi Takashio in England 2012 and getting the opportunity to visit Biwako Gakuen in 2014, and returning to Japan in 2017 and 2018. Thanks to these meetings Driving to Learn and the Assessment of Learning Powered mobility use (ALP) became known in Japan. This presentation will show what develops if an infant

Accuracy of gross tumour volume delineation with [68Ga]-PSMA-PET compared to histopathology for high-risk prostate cancer

Background: The delineation of intraprostatic lesions is vital for correct delivery of focal radiotherapy boost in patients with prostate cancer (PC). Errors in the delineation could translate into reduced tumour control and potentially increase the side effects. The purpose of this study is to compare PET-based delineation methods with histopathology. Materials and methods: The study population c

Minority rights in distress: A case study of Russian speakers’ resistance in response to education policy changes in Latvia before and during the Russo-Ukrainian War

In the past decade, studies have examined how the Russian-speaking minority reacted to changes in citizenship, language, and memory politics. However, one aspect that has not been studied is the response to educational policy changes during an ongoing conflict. This study investigates the resistance strategies of Russian-speaking mesolevel actors against minority education policy changes before an

Search for low-mass resonances decaying into two jets and produced in association with a photon or a jet at Formula Presented with the ATLAS detector

A search is performed for localized excesses in the low-mass dijet invariant mass distribution, targeting a hypothetical new particle decaying into two jets and produced in association with either a high transverse momentum photon or a jet. The search uses the full Run 2 data sample from LHC proton-proton collisions collected by the ATLAS experiment at a center-of-mass energy of 13 TeV during 2015

Mechanisms of chromatin binding by the MORC2 ATPase

MORC2 (Microorchidia CW type Zinc Finger protein 2) is a GHKL (gyrase, heat shock protein 90, histidine kinase, MutL) ATPase involved in chromatin remodeling and is highly conserved in eukaryotes. Mutations in the ATPase domain of MORC2 are known to cause neurodevelopmental disorders. MORC2 is recruited by the HUSH complex to target long, intronless transcription units such as LINE-1 retrotranspos

CD4+ T cells drive anti-tumor immunity elicited by in vivo dendritic cell reprogramming

Cancer immunotherapy employs the patients' own immune system to eradicate the tumor. The success of immunotherapies largely depends on an immune cell population, called T cells. T cells have the capacity to differentiate between healthy and malignant cells based on mutations that are displayed on the surface of cancer cells. After recognition of the tumor cell, T cells induce killing. However,

The Growth of Food Aid in Sweden – How Demand and Supply are Transforming Charitable Organisations

The purpose of this article is to describe and analyse the growth in food aid in Sweden, and how it affects the non-profit organisations providing it. The particular type of food aid in focus is large-scale collaborations between charitable non-profit organisations and the food industry, through which food surplus is turned into food aid for people in food insecurity. The first examples of such fo

Patient and primary tumor characteristics associated with lymph node metastasis in primary breast cancer

Kan spridning av bröstcancerceller förutspås? Bröstcancer är i dag världens vanligaste cancerform bland kvinnor. För att kunna fastställa en prognos som ger en bild över överlevnadsmöjligheten utförs flertalet undersökningar. Dels undersöks armhålan genom en ifrågasatt operation för att se om cancern spridits till armhålans lymfkörtlar. Frågan som ställs här är om det finns egenskaper hos bröstcaToday, breast cancer is the most common malignant disease among females worldwide. To predict the prognosis for outcome of the breast cancer, a number of prognostic factors are used such as the axillary lymph node status which is one of several factors to be evaluated when staging the disease. The axilla is routinely staged during sentinel lymph node biopsy excising a couple of lymph nodes to eval

Freshwater exploitation at Ajvide : Pitted ware culture fishing practises investigated through laser ablation facilitated strontium isotope analyses

The importance of marine resources for the Neolithic hunter-fisher-gathers of the Pitted Ware Culture of Gotland, Sweden, is well documented through zooarchaeological analyses and diet studies of human remains. Terrestrial areas were important for living and supplementing the diet but the extent of the terrestrial territories and regions of land use for different groups is largely unknown. The pre