A striking feature of nucleic acids and lipid membranes is that they all carry net negative charge and so is true for the majority of intracellular proteins. It is suggested that the role of this negative charge is to assure a basal intermolecular repulsion that keeps the cytosolic content suitably ‘fluid’ for function. We focus in this review on the experimental, theoretical and genetic findings

The Sagittarius dwarf spheroidal (Sgr dSph) galaxy is currently being accreted and disrupted by the tidal field of the Milky Way. Recent observations have shown that the central region of the dwarf hosts at least three different stellar populations, ranging from old and metal-poor over intermediate metal-rich to young metal-rich. While the intermediate-age metal-rich population has been identified

Concerns over the earth’s ability to sustain itself over the long term as a consequence of human consumption of natural resources points towards sustainable development. Since a large proportion of human consumption is linked to buildings and construction, this means managing the construction process in more sustainable ways. Strategies that target greater material efficiency and which promote cir

The insertion of rigid aliphatic or aromatic building blocks in polymer structures is an efficient synthetic strategy towards high-Tg polymer materials. In the present work, we have functionalized isosorbide 5-methacrylate with various aromatic lignin-inspired esters to yield a series of isosorbide-2-aryl carboxylate-5-methacrylate monomers (ArIMAs) as single regioisomers. The selection of phenyl

Psykologiska evidensbaserade interventioner som förmedlas via internet och mobila teknologier (Digital Mental Health) har potential att minska tröskeln för att få vård, samt minska svårigheter att få tillgång till behandling på grund av avstånd, kostnader, arbete och familjekonflikter eller begränsad kapacitet hos vårdgivare. Den här typen av hinder utgör en särskild utmaning för personer med deprEvidence-based psychological interventions delivered via the internet and mobile technologies (Digital Mental Health) hold the promise of reducing barriers to care, including difficulties accessing treatment because of distance, cost, work and family commitments, and limited provider capacity. Such barriers represent a particular challenge for individuals with depression and anxiety, that tend to

Riksbanken måste sluta experimentera med svensk ekonomi och återgå till en penningpolitik som ger långsiktig makroekonomisk stabilitet, skriver nationalekonomerna Fredrik NG Andersson och Lars Jonung.Riksbanken måste sluta experimentera med svensk ekonomi och återgå till en penningpolitik som ger långsiktig makroekonomisk stabilitet, skriver nationalekonomerna Fredrik NG Andersson och Lars Jonung.

The ubiquitous use of artificial intelligence (AI) can bring about both positive and negative consequences for individuals and societies. On the negative side, there is a concern not only about the impact of AI on first-order discrete individual rights (such as the right to privacy, non-discrimination and freedom of opinion and expression) but also about whether the human rights framework is fit f

Few recent developments have captured the human imagination as much as those within the field of artificial intelligence (AI). The increasing pervasiveness and ubiquity of AI affect both individual lives and society at large. Yet the human rights concerns raised in connection to AI have primarily concentrated around infringements of enumerated discrete rights, such as to privacy, non-discriminatio

The ubiquitous deployment of artificial intelligence (AI) technologies affects an array of human rights, raising concerns around issues of discrimination, privacy, freedom of expression, information and data protection. However, just as regulators and policy-makers call for technological design to respect existing human rights, others debate whether human rights are robust enough to counter new ch

Juvenile idiopathic arthritis (JIA) is a heterogenous inflammatory joint disease and the most commonrheumatic disease in children. Oligoarticular JIA (oJIA) is the major subgroup, which mainly affects fewand large joints, such as the knee. The immunological processes and key players driving inflammationwithin the affected joints are not well characterised. Research has primarily focused on adaptiv

This paper discussed construction industry’s ongoing battle with gender equality. Growing awareness of social sustainability responsibility has led to the mounting importance of human resources in the organisations. One perspective involves the focus on gender equality. Today women’s participation in the construction industry is still low except in times of acute labour shortages. This disproporti