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Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis

A genomic cosmid clone for human sex hormone binding globulin (SHBG), a liver-secreted plasma glycoprotein that binds sex steroids, was isolated with a previously characterized liver cDNA as probe. Southern blot analysis of genomic DNA indicated that only one SHBG gene is present in the human haploid genome. A 3.8 Kb Xba I-fragment of the clone containing the entire coding region of SHBG was seque

Business Rules Friendly or not so Business Rules Friendly Business Concepts Modelling - Early Experiences from a Business Rules Project on a Digital Vaccination Recommendation Service

WHO estimated in 2002 that 1.4 million children in the world would die from preventable diseases (World Health Organization, 2010). Each child is, or should be, immunized according to their national immunization schedule, which regulates i.e. vaccines and doses. Problems emerge when immigrant children should be transferred from one national vaccination schedule into another. This problem is quite

Magnetic phases near the Van Hove singularity in s- and d-band Hubbard models

We investigate the magnetic instabilities of the nondegenerate (s-band) and a degenerate (d-band) Hubbard model in two dimensions using many-body effects due to particle-particle diagrams and Hund’s rule local correlations. The density of states and the position of the Van Hove singularity change depending on the value of next-nearest-neighbor hopping t′. The Stoner parameter is strongly reduced i

Software Configuration Management Problems and Solutions to Software Variability Management

These days more and more software is produced as product families. Products that have a lot in common, but all the same vary slightly in one or more aspects. Developing and maintaining these product families is a complex task. Software configuration management (SCM) can, in general, support the development and evolution of one single software product and to some degree also supports the concept of

Integrating microorganism and macroorganism dispersal: modes, techniques and challenges with particular focus on co-dispersal.

Whatever their size and the ecosystem they live in, all organisms may disperse at some stage of their life cycle. Dispersal dynamics are to a varying extent dependent on organismal size, life history, ecological niche, survival capacities and phylogeny. Moves towards a synthesis in dispersal ecology have focused primarily on vertebrates and higher plants, yet recent studies suggest that the disper