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Anal fistulae - Three-dimensional endoanal ultrasound and outcomes of collagen plug treatment

Bakgrund: Behandling av komplicerade analfistlar försätter att vara en stor utmaning. Tidiga studier på anal fistelplugg (AFP) visade att högt andel av patienter blir bra men senare har man rapporterad väldig varierande behandlingsframgång (13-100%) för uppföljningstider på 6-24 månader. Kunskap om de morfologiska fynd som kan relateras till framgångsrik eller misslyckad operationsresultat efter ABackground: The treatment of complex anal fistulae remains a therapeutic challenge. Early anal fistula plug (AFP) studies showed high success rates, while later reports demonstrated success rate of 13-100% at usual follow-up of 6-24 months. Very little is known about morphological findings related to success and failure of the AFP, especially if three-dimensional (3D) endoanal ultrasound (EAUS) is

Spatiotemporal variability of dust storm source susceptibility during wet and dry periods: The Tigris-Euphrates River Basin

This study develops a framework for spatiotemporal modeling of dust storm source susceptibility in a critical case study, the Tigris-Euphrates River Basin, as a significant source of dust storms in the Middle East. The study period was divided into four periods, 2000–2004 (hydrological dry year), 2005–2007 (hydrological wet year), 2008–2012 (hydrological dry year), and 2013–2021 (hydrological wet

Historical diffusion of nuclear, wind and solar power in different national contexts : implications for climate mitigation pathways

Climate change mitigation requires rapid expansion of low-carbon electricity but there is a disagreement on whether available technologies such as renewables and nuclear power can be scaled up sufficiently fast. Here we analyze the diffusion of nuclear (from the 1960s), as well as wind and solar (from the 1980-90s) power. We show that all these technologies have been adopted in most large economie

Unveiling the Impact of Organic Spacer Cations on Auger Recombination in Layered Halide Perovskites

A library of large organic cation spacers is available for engineering the performance of layered two-dimensional (2D) halide perovskite devices. Despite extensive photophysics studies, there remains a research gap over the structure-function relations in 2D perovskites, especially the underlying factors influencing the Auger recombination (AR) process. Herein, the contributions of exciton binding

Modeling coupled nitrification-denitrification in soil with an organic hotspot

The emission of nitrous oxide (N2O) from agricultural soils to the atmosphere is a significant contributor to anthropogenic greenhouse gas emissions. The recycling of organic nitrogen (N) in manure and crop residues may result in spatiotemporal variability in N2O production and soil efflux which is difficult to capture by process-based models. We propose a multi-species, reactive transport model t

Non-parametric Envelope Estimation for the Matched Window Reassignment

The reassigned spectrogram is a powerful tool for analysing non-stationary signals, and in an ideal setting it gives perfect time and frequency localisation. A method very well suited for oscillating transient signals is the matched window reassignment, which requires a matching window, i.e. the envelope of the transient, to be known or estimated beforehand. This paper proposes a novel method for

Parameter Estimation from the Cross-Spectrogram Reassignment Vectors

In this paper we propose a novel technique to estimate the parameters of two Gaussian envelope oscillatory signals, with the same time-locations and oscillatory frequencies but possibly different phases. The phase difference and the length of the Gaussian envelope are estimated directly from the slopes of the corresponding cross-spectrogram reassignment vectors. Including the phase difference and

The datafication of pain : : Trials and tribulations in measuring phantom limb pain

This article takes the phenomenon of phantom limb pain (PLP), and a therapeutic technology designed to treat it, as springboards to critically consider a transformation: from deeply subjective experiences into quantitative data. Drawing upon ethnographic fieldwork on neuroprosthetic development, I examine an international clinical trial coordinated in Sweden using neuromuscular activation, machine

Bilinear Parameterization for Non-Separable Singular Value Penalties

Low rank inducing penalties have been proven to successfully uncover fundamental structures considered in computer vision and machine learning; however, such methods generally lead to non-convex optimization problems. Since the resulting objective is non-convex one often resorts to using standard splitting schemes such as Alternating Direction Methods of Multipliers (ADMM), or other subgradient me

Homotopy Continuation for Sensor Networks Self-Calibration

Given a sensor network, TDOA self-calibration aims at simultaneously estimating the positions of receivers and transmitters, and transmitters time offsets. This can be formulated as a system of polynomial equations. Due to the elevated number of unknowns and the nonlinearity of the problem, obtaining an accurate solution efficiently is nontrivial. Previous work has shown that iterative algorithms

Localization Of Multiple Jammers In Wireless Sensor Networks

Wireless sensor networks are susceptible to jamming attacks that can result in communication breakdowns. Preemptive measures to prevent jamming attacks is an active research field, but to stop an ongoing attack often requires that one is able to locate jammers in order to neutralize them. Several methods exist for the case when the network is corrupted by a single jammer, although these generally

Structure and ion-release mechanism of P IB-4-type ATPases

Abstract Transition metals, such as zinc, are essential micronutrients in all organisms, but alsohighly toxic in excessive amounts. Heavy-metal transporting P-type (PIB) ATPases are crucial forhomeostasis, conferring cellular detoxification and redistribution through transport of these ionsacross cellular membranes. No structural information is available for the PIB-4-ATPases, the subclasswith the