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Persistent regional frontotemporal hypoactivity in violent offenders at follow-up.

Since cross-sectional brain-imaging studies demonstrating frontotemporal cerebral hypoactivity in violent offenders have generally been carried out around the time of trial and sentencing, the findings might be influenced by the stressful situation of the subjects. It seems that no group of offenders with this finding has yet been followed longitudinally. We have re-examined nine offenders convict

Modeling the cost-effectiveness of treatment of rheumatoid arthritis with rituximab using registry data from Southern Sweden

Objectives: The aim of this study was to estimate the cost-effectiveness of rituximab in patients not responding adequately to the first tumor necrosis factor (TNF) inhibitor using a model constructed to predict resource consumption and health outcomes in a population-based registry of biological treatments in Southern Sweden (SSATG). Methods: The model was developed as a discrete event simulation

Understanding the 3D structure of GaAs nanowires

The effects of lamellar twinning in epitaxial particle-assisted GaAs <111>B nanowires are investigated in an extensive high resolution electron microscopy (HRTEM) study of the low index zones <-100>, <-1-10>, <1-1-1> and <1-1-2>. As these directions are non-parallel to the (-1-1-1) twin planes we find that the twin segments exhibit two different zone axes as a consequence of twinning. In the first

Morphology, evolution and stratigraphic distribution in the Middle Ordovician conodont genus Microzarkodina

Microzarkodina is a genus of mainly Middle Ordovician conodonts that has its centre of distribution in Baltoscandia, and much less commonly occurs in southern China, Australia, Argentina and Laurentia. In Baltica a series of species, Microzarkodina russica n. sp., M. flabellum, M. parva, M. Bella, M. Hagetiana and M. ozarkodella, established themselves successfully. The succession of species range

Photocurrent Spectra and Fast Kinetic Studies of P3HT/PCBM Mixed with a Dye for Photoconversion in the Near-IR Region

Photoconversion properties are demonstrated for a device based on a small dye molecule, absorbing light in the near-IR region, mixed with two organic charge transport materials and together forming a dye-sensitized organic bulk heterojunction. The organic dye molecule, phthalocyanine (1,4,8,11,15,18,22,25-octabutoxy-29H,31H-phthalocyanine), mixed with a blend of poly(3-hexylthiophene) (P3HT) and 1

Evaluation of third trimester uterine artery flow velocity indices in relationship to perinatal complications.

Objective. Uterine artery Doppler is becoming a routine part of pregnancy surveillance in high-risk pregnancies. Which blood flow velocity waveform index to measure is debated and the 'notch' in early diastole is not widely accepted, as it is a subjective measure. The aim of the present study was to evaluate the different indices in the prediction of adverse outcome of pregnancies suspected for in

Two 3D supramolecular architectures from zinc hydrogen aconitate 1D polymers

The reaction of Zn(NO3)(2)center dot 3(H2O) with trans-aconitic acid, in presence of chelating Lewis bases, leads to the formation of the 1D polymers [Zn(N-N)(LH)] center dot nH(2)O, where LH3 = trans-aconitic acid, 1 : N-N = 1,10-phenanthroline (phen), n = 1, 2 : N-N = 2,2'-bipyridine (bpy), n = 2. 3D supramolecular assemblies are constructed through H-bonding and stacking interactions. (C) 2006

A novel mammalian display system for the selection of protein-protein interactions by decoy receptor engagement

The emerging field of proteomics has created a need for new high-throughput methodologies for the analysis of gene products. An attractive approach is to develop systems that allow for clonal selection of interacting protein pairs from large molecular libraries. In this study, we have characterized a novel approach for identification and selection of protein-protein interactions, denoted SPIRE (se

Effect of postinduction nutrient feed composition and use of lactose as inducer during production of thermostable xylanase in Escherichia coli glucose-limited fed-batch cultivations

Escherichia coli is a microorganism routinely used in the production of heterologous proteins. The overexpression of a xylanase (Xyn10A Delta NC), which originated from the thermophile Rhodo-thermus marinus cloned under the control of the strong T7/lac promoter in a defined medium (mAT) using a substrate-limited feed strategy, was however shown to impose a significant metabolic burden on host cell

Cell lysis of competitors and osmotrophy enhance growth of the bloom forming alga Gonyostomum semen

Abstract in UndeterminedThe nuisance alga Gonyostomum semen (Raphidophyceae) is known to form dense blooms in many freshwater bodies, and has increased its distribution and abundance. However, information on the mechanisms behind bloom formation and maintenance is scarce. Field observations indicate that G. semen may be favored in humic lakes, In the present study, we performed controlled laborato

Multireference Calculations of the Phosphorescence and Photodissociation of Chlorobenzene

Multireference complete active space self-consistent-field (CASSCF) and multireference CASSF second-order perturbation theory (MSCASPT2) calculations were performed on the ground state and a number of low-lying excited singlet and triplet states of chlorobenzene. The dual phosphorescence observed experimentally is clearly explained by the MSCASPT2 potential-energy curves. Experimental findings reg

Preparation of lipases for use in organic solvents

The efficiency of different preparations of lipases was evaluated in organic solvents. Lipases from Humicola lanuginosa, Candida rugosa, Rhizomucor miehei and Pseudomonas cepacia were adsorbed onto the surfactant sorbitan monostearate (Span 60) and the specific activities were compared in hexane to crude powder (used straight from the bottle) and lipase freeze-dried from buffer solution. Lipases a

Genetic engineering of protein-peptide fusions for control of protein partitioning in thermoseparating aqueous two-phase systems

Genetic engineering has been used for the fusion of peptides, with different length and composition, on a protein to study the effect on partitioning in aqueous two-phase systems containing thermoseparating polymers. Peptides containing 2-6 tryptophan residues or tryptophan plus 1-3 lysine or aspartate residues, were fused near the C-terminus of the recombinant protein ZZT0, where Z is a synthetic

Predictive value of soluble haemoglobin scavenger receptor CD163 serum levels for survival in verified tuberculosis patients

Pre-treatment serum levels of sCD163 were measured in a cohort of 236 suspected tuberculosis (TB) cases from Guinea-Bissau, with a median follow-up period of 3.3 years (range 0-6.4 years). In 113 cases, the diagnosis of TB was verified by positive sputum microscopy and/or culture. Among the verified TB cases, a decreased survival rate was found in 27 patients with sCD163 levels above the upper ref

Mixing in circular and non-circular jets in crossflow

Coherent structures and mixing in the flow field of a jet in crossflow have been studied using computational (large eddy simulation) and experimental (particle image velocimetry and laser-induced fluorescence) techniques. The mean scalar fields and turbulence statistics as determined by both are compared for circular, elliptic, and square nozzles. For the latter configurations, effects of orientat