Första delen i denna avhandling fokuserar på 'Imaging Mass Spectrometry' (IMS), en analytisk teknik med kartografiska egenskaper. Denna teknik används dock inte för att kartlägga geografiska terränger, utan för att skapa kartor över det kemiska landskapet i biologiska prover, från vävnadssnitt av organ eller tumörer till enskilda celler. Dessa kartor visar med hög precision var olika molekyler, såThe development of imaging technologies and brain models is crucial for advancements in neurotherapeutic drug discovery and development. They assume a critical role in evaluating essential parameters such as drug blood-brain barrier (BBB) permeation, distribution, and metabolism, all of which are vital for the development of safe and effective medications. In the first part of this thesis, we expl

This article examines how work plays a major role in Danish Greenland literature – often with the workplace as a zone of conflict. At first, a literary historical presentation introduces the tradition followed by an analysis of Jørgen Liljensøe’s novel Barakkerne (1977). Lastly, newer Danish Greenland literature by Kim Leine and Iben Mondrup are discussed. The approach is primarily place-theoretic

Nymaterialistisk analyse af Kaspar Colling Nielsens værker Mount København (2010), Den danske borgerkrig 2018-24 (2013) og Det europæiske forår (2017). Værkerne læses som en trilogi med fokus på økokritik, det posthumane og kropsmaterialisme, og vi spørger: Hvad er et menneske, hvad er teknologi - og hvad sker der, når alt flyder sammen?

This article explores the impact of the ‘Quadruple Whammy’ consisting of Brexit, COVID-19, Conflicts (Russia-Ukraine and Israel-Palestine), and Natural disasters on the food supply chain in Europe. This research adopted a two-phase methodology comprised of e-Delphi technique followed by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) approach within the context of t

Purpose: Forehead flaps are commonly used in oculoplastic surgery to cover defects after tumor excision. Blood perfusion is vital for flap survival. The aim of this study was to monitor the perfusion in forehead flaps and investigate the impact of flap length and thickness. Methods: Nineteen forehead flaps in patients undergoing direct brow lift were studied. Perfusion was monitored using laser sp

När stjärnor bildas omges de av en skiva bestående av gas, stoft och is. Detta är den protoplanetära skivan där de fasta beståndsdelarna växer från mikrometerstora dammpartiklar till planeter. Små stoftpartiklar kan växa genom kollisioner, men att nå tillräckliga partikelstorlekar och tillräckligt hög partikelkoncentration är utmanande. I denna avhandling undersöker jag om den så kallade islinjen As stars form, they are surrounded by a disc composed of gas, dust and ice – the protoplanetary disc, where solids grow from micrometre-sized dust to planets. Small dust grows readily by collisions. However, it is challenging to reach high enough particle sizes and dust-to-gas-ratios for continued growth to planetesimals – kilometre-sized and larger planetary building blocks. In this thesis I expl

Flying foxes of the genus Pteropus are amongst the largest fruit bats and potential long-range pollinators and seed dispersers in the paleotropics. Pteropus giganteus (currently P. medius) is the only flying fox that is distributed throughout the Indian mainland, including in urban and rural areas. Using GPS telemetry, we mapped the home ranges and examined flight patterns in P. giganteus males ac

The slug moth family Limacodidae is a cosmopolitan group of economic importance, but its higher level systematics remains poorly understood. Here, we present a robust, higher level phylogenetic framework for Palaearctic and Indomalayan members of the family using sequence capture data of 148 nuclear protein-coding and 13 mitochondrial markers from 145 samples of 126 species in 67 genera representi

In the North Sea, Tripos and Dinophysis are commonly occurring mixotrophic planktonic dinoflagellate genera. In order to understand their bloom dynamics, an occurring bloom dominated by T. furca and D. norvegica was followed for several days. High cell abundances of these species were located to estimate: in situ growth rates from cell cycle analyses, depth distributions, growth rates sustained by

Pesticide use in agricultural landscapes creates environmental contamination that is heterogenous in space and time. Mobile organisms, such as bees, are exposed to multiple contamination sources when visiting patches that vary in the amount, timing and toxicity of pesticides used. Yet, environmental risk assessments (ERA) typically fail to consider this heterogeneity, in part because of the comple

Introduktion: Dataspelande är en väldigt vanlig fritidssyssla och en majoritet av svenska ungdomar uppger att de spelar dataspel dagligen. En minoritet av dessa utvecklar ett problematiskt spelbeteende, ett fenomen som fått formellt erkännande i och med att diagnosen Gaming Disorder (GD) inkluderats i diagnossystemet ICD-11. Nu efterfrågar både barn- och ungdomspsykiatrin (BUP), skolhälsovården oc

Purpose: To analyze structural changes in the macular retinal layers and sub-foveal choroidal thickness (SFCT) in eyes after macula-on rhegmatogenous retinal detachment (RRD) repair by pars plana vitrectomy with either silicone oil (SO) or gas tamponade, and the effect of these changes on visual acuity. Patients and methods: Retrospective study which included 26 eyes in the SO Group and 32 in the

At the present conjuncture of political, economic, social, and ecological crises, it is important to pay attention to the ways in which intensifying demands for equality, sustainability and social inclusion are met in education policy. In this article, we present results from a critical discourse analysis of an EU council recommendation on ‘microcredentials’ – credits for short courses primarily o

Here we report on an experimental and theoretical investigation of the long-wavelength infrared (LWIR) photoresponse of photodetectors based on arrays of three million InP nanowires with axially embedded InAsP quantum discs. An ultra-thin top indium tin oxide contact combined with a novel photogating mechanism facilitates an improved LWIR normal incidence sensitivity in contrast to traditional pla

The first measurements of skewness and kurtosis of mean transverse momentum (〈pT〉) fluctuations are reported in Pb–Pb collisions at sNN = 5.02 TeV, Xe–Xe collisions at sNN = 5.44 TeV and pp collisions at s=5.02 TeV using the ALICE detector. The measurements are carried out as a function of system size 〈dNch/dη〉|η|

Background: Breathlessness is common in the population and can be related to a range of medical conditions. We aimed to evaluate the burden of breathlessness related to different medical conditions in a middle-aged population. Methods: Cross-sectional analysis of the population-based Swedish CArdioPulmonary bioImage Study of adults aged 50–64 years. Breathlessness (modified Medical Research Counci

Molecular beacons (MBs) have been used on surfaces for detecting oligonucleotides. Attempts to use them intracellularly for monitoring mRNA content have been made, however, without any clear conclusion regarding the reliability of the method, mainly due to false positive signals. To reach an understanding of the intracellular fate of MBs, a critical question remains: how long after MB delivery and

Few studies have investigated the offspring of women with anorexia nervosa (AN). The aim of this study was to examine perinatal status, mental and physical health in the offspring of mothers with a history of AN. Fifty-one individuals with adolescent-onset AN and 51 matched controls (COMP) have been followed prospectively. Presently, 30 years after AN onset, at a mean age of 44 years, female parti

Deficiencies of the early complement components of the classical pathway (CP) are well-documented in association with systemic lupus erythematosus (SLE) or SLE-like syndromes and severe pyogenic infections. Among these, complete C1s deficiency has been reported in nine cases so far. Here, we describe a 34-year-old male patient who presented with severe, recurrent infections since childhood, includ