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Neuropathological findings in Down syndrome, Alzheimer's disease and control patients with and without SARS-COV-2 : preliminary findings

The SARS-CoV-2 virus that led to COVID-19 is associated with significant and long-lasting neurologic symptoms in many patients, with an increased mortality risk for people with Alzheimer's disease (AD) and/or Down syndrome (DS). However, few studies have evaluated the neuropathological and inflammatory sequelae in postmortem brain tissue obtained from AD and people with DS with severe SARS-CoV-2 i

Främjande av psykisk hälsa hos primärvårdspatienter: Utvärdering av en mindfulness-baserad kognitiv terapigrupp

Psykisk ohälsa klassas idag som ett av de stora folkhälsoproblemen och det har gradvis skett en kraftig ökning av den andel som söker vård (OECD, 2015). Tillgången till psykologisk behandling är idag begränsad till följd av bristen på kvalificerad personal inom området. Individuell terapi är kostsam för den skattefinansierade sjukvården, vilket framhäver betydelsen av gruppterapi som en kostnadsefMental health remains a major public health concern, with a notable rise in treatment-seeking individuals (OECD, 2015). However, limited access to psychological interventions persists due to a shortage of qualified professionals. Given the excessive cost of individual therapy within publicly funded healthcare systems, the focus on cost-effect group therapy becomes imperative (Sundquist et al., 201

"Att vara verklig i terapin" En kvalitativ studie om psykoterapeuters självutlämnande och dess påverkan på den terapeutiska processen

Självutlämnande är en terapeutisk intervention som beskrivs som en av de mest hjälpsamma redskapen i en behandlingsprocess. Självutlämnande innebär att en terapeut delar personlig information eller erfarenheter om sig själv till sin klient eller när det används som en omedelbar respons på klienten i terapirummet. Studiens syfte var att utforska psykoterapeuters upplevelser av självutlämnande i terSelf-disclosure is a therapeutic intervention that is described as one of the most helpful tools in a treatment process. Self-disclosure implies that a person shares personal information or experiences about themselves to their client or when it´s used as an immediate response towards the client in the therapy room. The aim of the study was to investigate psychotherapists' experiences of self-

Meningsfull förändring inom psykoterapi - utveckling och initial validering av instrument för att mäta meningsfull förändring utifrån individuella språkliga beskrivningar

Meningsfull förändring är en central och djupt rotad strävan inom det psykoterapeutiska området. Terapeutens roll handlar om att hjälpa patienten att skapa förändring som är meningsfull för individen. Genom att mäta meningsfull förändring kan terapeuten se vilka interventioner som verkligen fungerar. Studien syftar till att utveckla och initialt utvärdera ett instrument för att mäta meningsfull föMeaningful change is a central and deeply rooted endeavor within psychotherapy. The study aims to develop and initially evaluate an instrument to measure meaningful change in psychotherapy. The therapist's role is to assist the patient in creating change that is meaningful to the individual. By measuring meaningful change, the therapist can identify which interventions are truly effective. The

Komplex PTSD (C-PTSD) - en (o)känd diagnos?

I och med införandet av ICD-11, 2018, tillkom diagnosen Komplex PTSD (C- PTSD) i den internationella klassifikationen av sjukdomar och Socialstyrelsen arbetar just nu med den svenska översättningen som förväntas publiceras någon gång under 2025 på WHO:s plattform. Syftet med denna studie var att undersöka hur kunskapsläget bland behandlare med lägst steg 1-kompetens såg ut inom vuxenpsykiatrin. DeSince the introduction of ICD-11 in 2018, C-PTSD has been a diagnosis in the international classification of diseases. Socialstyrelsen is currently working on the Swedish translation, which is expected to be published sometime in 2025. However, C-PTSD as a concept, has been around longer than that. The aim of this study has been to examine the level of knowledge regarding C-PTSD among clinicians,

Planning tools and methods for systems facing high levels of distributed energy resources

It is important for utilities to plan for Distributed Energy Resources (DER) uptake by representing and modelling their characteristics using appropriate assumptions, methods and tools. Large-scale DER deployment impacts power flows and power system performance in various complex ways as well as potentially contributing to ancillary services. In this paper, we explore state of the art planning met

Household energy transition in metropolitan and rural Nepal: Analysing meaningful energy transition through the Energy Cultures Framework

Nepal has made major progress in expanding its national electricity grid, creating the potential for a double transition as increased access benefits the energy-poor and sets the infrastructural ground for transition to renewables. Many households, however, continue to rely on traditional and transition fuels such as firewood and gas. This problem is both social and environmental, as without the ‘

Seeding change through Community Supported Agriculture? The prefigurative potential of CSAs in South-Holland, The Netherlands

Conventional agrifood systems significantly contribute to environmental degradation. While Community Supported Agriculture initiatives (CSAs) may provide insights into alternative agrifood systems, few studies have investigated challenges to their engagement with prefigurative processes. Through a case study of nine CSAs in South-Holland, the Netherlands, this thesis explores the extent to which C

An Analysis of the Impact of Industrial Growth on Housing Affordability in Skellefteå, Sweden

This study investigates the impact of industrial growth on housing affordability in Skellefteå, Sweden, utilizing a combination of quantitative and qualitative data sources. The analysis encompasses data from Statistics Sweden, interviews, and surveys to explore the complex relationship between industrial expansion, population dynamics, and housing affordability. The findings reveal a substantial

Bridging inner and outer transformation for the mainstreaming of nature-based solutions

Cities face multiple social-ecological challenges, which nature-based solutions (NBS) promise to address. Strategies to mainstream NBS have only achieved partial success, hence recent studies suggest that inner dimensions - mindsets and transformative capacities - must be mainstreamed simultaneously. This study investigates municipal employees' engagement with inner dimensions, its impact on s

Understanding career transitions of applied researchers to universities : evidence from Germany

This paper analyses the conditions and factors influencing non-university researchers' career transitions back into academia. Using affiliation data in publications of German researchers, their cross-sector career transitions from the public research organisation Fraunhofer-Gesellschaft and industry to universities are analysed. Although the rate of transitions is small, there are distinctive wind

Raising the bar : genus-specific nested PCR improves detection and lineage identification of avian haemosporidian parasites

Avian haemosporidian parasites are useful model organisms to study the ecology and evolution of parasite-host interactions due to their global distribution and extensive biodiversity. Detection of these parasites has evolved from microscopic examination to PCR-based methods, with the mitochondrial cytochrome b gene serving as barcoding region. However, standard PCR protocols used for screening and

Grazer-induced bioluminescence in Alexandrium mediterraneum but not in Alexandrium andersonii

Phytoplankton and zooplankton interactions are vital in regulating nutrient cycles and productivity in aquatic ecosystems. Nevertheless, zooplankton account for the majority of phytoplankton mortality in the ocean. Due to predation pressures, phytoplankton have evolved several defensive traits, many of them being inducible defenses such as toxin production, colony size alterations, swimming behavi

Toward a more expansive discourse in a changing world : An analysis of political leaders’ speeches on biodiversity

Speeches delivered in the Conference of the Parties (COPs) to the Convention on Biological Diversity represent leading discourses about biodiversity conservation. The discourse shared by high-level politicians is especially influential in the financing and decision-making process of global biodiversity governance. However, the speeches given in the COPs have not been the subject of systematic anal

Who changes what, when and where? Elaborating postponement when integrating hardware and software objects in global supply chains

Purpose: The postponement principle concerns defining when and where value is added, usually referring to hardware components for physical products. However, in modern supply chains, software’s importance is increasing, impacting the timing and location of value-adding operations. Lacking insights into software-driven implications for postponement, we aim at elaborating on the postponement princip

Diastolic Filling in Patients After Heart Transplantation Is Impaired Due to an Altered Geometrical Relationship Between the Left Atrium and Ventricle

BackgroundThe geometrical relationship between atrial and ventricular short‐axis cross‐sectional area determines the hydraulic forces acting on intracardiac blood. This is important for diastolic filling. In patients undergoing heart transplantation (HTx), the left atrium is often enlarged as a result of the standard surgical technique. We hypothesized that diastolic filling in HTx patients is aff

Beyond carbon? Assessing the carbon lock-in risk of hydrogen projects in northern Germany

Hydrogen could play a crucial role in decarbonizing no-regret sectors, such as the steel or chemical industry. It can be produced in different ways, e.g., with renewable energy (green hydrogen) or fossil gas and Carbon Capture and Storage (blue hydrogen). Blue hydrogen could pose a risk of perpetuating fossil fuel dependence. Guided by the carbon lock-in theory, I analyzed the northern German hydr

Oleogels as controlled delivery systems for probiotics

A new encapsulation strategy for probiotics is highly needed to tackle the challenge of significant viability loss of bacteria during storage and passage through the gastrointestinal system. A new controlled delivery system for probiotics based on EC oleogels is proposed in this thesis. A relatively non-complicated in vitro lipolysis model was established to evaluate the relative conversion from t