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Background: The preclinical patterns of biological markers for Alzheimer's disease (AD) in vivo need further exploration. The aim of this study was therefore to investigate CSF biomarkers, regional cerebral blood flow (rCBF) and cognitive performance in cognitively healthy older individuals. Method: Within a 2-week period, 32 cognitively healthy older individuals underwent CSF analysis, rCBF m
To investigate biomarker patterns in rheumatoid arthritis (RA) with extraarticular manifestations.
Background: Photoallergic contact dermatitis (PACD) is an uncommon condition, and there is a lack of validated criteria for its diagnosis. Objective: To identify a set of relevant criteria to be considered when suspecting a diagnosis of PACD and to assess the reproducibility of these criteria. Methods: This was a diagnostic item selection and reliability study performed between July 2012 and Octob
Background There are limited data comparing radiofrequency catheter ablation with antiarrhythmic drug therapy as first-line treatment in patients with paroxysmal atrial fibrillation. Methods We randomly assigned 294 patients with paroxysmal atrial fibrillation and no history of antiarrhythmic drug use to an initial treatment strategy of either radiofrequency catheter ablation (146 patients) or the
We investigated neural distinctions between inflectional and derivational morphology and their interaction with lexical frequency using the mismatch negativity (MMN), an established neurophysiological index of experience-dependent linguistic memory traces and automatic syntactic processing. We presented our electroencephalography (EEG) study participants with derived and inflected words of variabl
Sterically hindered amines, such as 2-amino-2-methyl-1-propanol (AMP), are an interesting alternative to the amines used in conventional CO2 absorption processes in industrial applications. One reason for this is because the carbamate formed is not stable, which may be beneficial during the regeneration of the amine solution in terms of a reduced energy requirement. This paper presents experiment
We demonstrate that the crystal structure of InAs nanowires call be controlled with nanowire diameter and growth temperature. At small diameters, the nanowires exhibit a wurtzite Structure. As the diameter is increased, there is a crossover to the zinc blende structure. The crossover is less sharp at lower growth temperature and L, the crossover diameter decreases as the growth temperature is incr
BACKGROUND: A novel way to evaluate muscle strength and functioning in the lower limbs is to measure how high a person could step up on a platform, the so called Maximal Step-up Test (MST). Studies of healthy persons and overweight women have shown that the maximal step-up height (MSH) is associated with both muscle strength and physical function, but no study has assessed persons after stroke. OB
Exposure, sensitivity and adaptive capacity are essential, albeit theoretically vague, components of climate vulnerability. This has triggered debate surrounding how these factors can be translated into, and understood in, an empirical context subject to present and future harm. In this article, which draws on extensive fieldwork in the Lake Victoria Basin of Kenya and Tanzania, we illustrate how
Background: It is known that some patch-test preparations containing disperse dyes contain impurities with unknown relevance for the development or elicitation of contact allergy. Objective: To evaluate the significance of the impurities found in the commercial dyes Disperse Orange 1 (DO1) and Disperse Yellow 3 (DY3) regarding contact allergy in patients with known sensitivity to them. Metho
Background: Patch testing has been used for more than 100 years as the best means to diagnose contact allergy. The increased use of the technique makes standardization of the methodology most important. Progress in the standardization of the patch test technique has been made through guidelines. Objectives: To investigate the intra-individual and inter-individual differences in reading of patch
The predominant forms of arsenic (As) in anoxic and oxic environments are As(III) and As(V), respectively, and the fate of these forms is influenced by interactions with mineral surfaces and organic matter (OM). Interactions between As(V) and OM are believed to occur mainly via iron(Fe)-bridges in ternary Fe-arsenate complexes, but direct evidence for these interactions are scarce. Furthermore, si
Unprecedented global challenges demand wide-reaching societal modification to ensure life support functions and human well-being. In the absence of adequate international responses to climate change and the need for place-based adaptation, local governments have a pivotal role in fostering sustainability transitions. In this context, the importance of ecosystem-based adaptation is increasingly rec
This article discusses the relation between knowing, learning and teaching in relation to early Palaeolithic technologies. We begin by distinguishing between three kinds of knowledge: knowing how, knowing what and knowing that. We discuss the relation between these types of knowledge and different forms of learning and long-term memory systems. On the basis of this analysis, we present three types
On the basis of data from Swedish, this paper examines the Small Clause Hypothesis (Kush & Lindahl 2011, Kush, Omaki & Hornstein 2013) proposed to account for relative clause (RC) extractions in Mainland Scandinavian. The hypothesis predicts that extraction possibilities differ for relative clauses in the complement of verbs which select and verbs which do not select a small clause (SC), a
This article examines evidence for violence as reflected in skull injuries in 378 individuals from Neolithic Denmark and Sweden (3,9001,700 BC). It is the first large-scale crossregional study of skull trauma in southern Scandinavia, documenting skeletal evidence of violence at a population level. We also investigate the widely assumed hypothesis that Neolithic violence is male-dominated and resul
