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Pulmonary collapse alone provides effective de-airing in cardiac surgery: a prospective randomized study.

We previously described and showed that the method for cardiac de-airing involving: (1) bilateral, induced pulmonary collapse by opening both pleurae and disconnecting the ventilator before cardioplegic arrest and (2) gradual pulmonary perfusion and ventilation after cardioplegic arrest is superior to conventional de-airing methods, including carbon dioxide insufflation of the open mediastinum. Th

Hydrodynamics of very shallow lakes - A study in Lake Krankesjön, Sweden

Shallow lakes have great ecological and recreational values. They are also largely affected by humans, mainly through eutrophication, and great efforts are therefore being put into the understanding of these ecosystems. The knowledge is however not complete, and more research is needed to manage these lakes in a sustainable way. The physical characteristics that are special for shallow lakes compa

Open chromatin and diabetes risk.

A new study has identified a large number of open chromatin regions harboring active regulatory elements in human pancreatic islets. A type 2 diabetes-associated SNP in TCF7L2 was found to be located in a region of allele-specific open chromatin and shows allele-specific enhancer activity, suggesting a potential mechanism for this disease association.

Otoacoustic emissions and improved pass/fail separation using wavelet analysis and time windowing

A new method is presented for the purpose of improving pass/fail separation during transient evoked otoacoustic emission (TEOAE) hearing screening. The method combines signal decomposition in scales using the discrete wavelet transform, non-linear denoising and scale-dependent time windowing. The cross-correlation coefficient between two subaveraged, processed TEOAE signals is used as a pass/fail

Discriminatory analysis of biochip-derived protein patterns in CSF and plasma in neurodegenerative diseases

The role of biomarkers in neurodegenerative diseases has been emphasized by recent research. Future clinical demands for identifying diseases at an early stage may render them essential. The aim of this pilot study was to test the analytical performance of two multiplex assays of cerebral markers on a well-defined clinical material consisting of patients with various neurodegenerative diseases. We

Robust NQR Signal Detection

Nuclear quadrupole resonance (NQR) is a spectroscopic technique that can be used to detect many high explosives and narcotics. Unfortunately, the measured signals are weak, thereby inhibiting the widespread use of the technique. Current state-of-the-art detectors, which exploit realistic NQR data models, assume that the complex amplitudes of the NQR signal components are known, to within a multipl